A5037228793- Genomics and Phylogenetic Studies
- Food Quality and Safety Studies
- Identification and Quantification in Food
- Ecology and Conservation Studies
- Natural product bioactivities and synthesis
- Phytochemicals and Antioxidant Activities
- Genetic diversity and population structure
- Phytochemistry and Biological Activities
- Seed and Plant Biochemistry
- Ichthyology and Marine Biology
- Phytochemistry and Bioactive Compounds
- Seaweed-derived Bioactive Compounds
- Aquaculture disease management and microbiota
- Agriculture, Soil, Plant Science
- Plant Pathogens and Fungal Diseases
- Fish Biology and Ecology Studies
- Traditional and Medicinal Uses of Annonaceae
- Nutrition, Health and Food Behavior
- Phytochemistry and biological activities of Ficus species
- Polysaccharides and Plant Cell Walls
- Phytochemical compounds biological activities
- Coleoptera Taxonomy and Distribution
- Traditional Chinese Medicine Analysis
- Liver Disease Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
Jeju TechnoPark
2013-2025
Myongji Hospital
2015
Hankyong National University
2008-2012
Rural Development Administration
2003-2004
C3HC4-type RING zinc finger proteins are known to be essential in the regulation of plant processes, including responses abiotic stress. Here, we identify, clone and examine first protein (BrRZFP1) from Brassica rapa under stress conditions. Phylogenetic analysis BrRZFP1 revealed strong sequence similarity Arabidopsis that induced by stresses. Diverse environmental stresses, salt cold, were found induce transcripts greater than eightfold B. rapa. Additional induction was shown hormone...
No effective therapeutics have yet been developed for pancreatic cancer. 2-Methoxy-4-vinyl phenol (2M4VP), a member of the class phenols, has demonstrated to anti-inflammatory properties and cause cell cycle arrest making it an attractive candidate drug treatment cancer.The effects 2M4VP were examined in Panc-1 SNU-213 human cancer cells.2M4VP had anticancer on lines, SNU-213. reduced viability cells by inhibiting expression nuclear antigen (PCNA) protein. also suppressed migratory activity...
The cytoprotective effect of quercitrin (QR) against oxidative stress induced cell damage by hydrogen peroxide (H2O2) in Chinese hamster lung fibroblast (V79-4) cells was investigated. QR evidenced a scavenging 1,1-diphenyl-2-picrylhydrazyl (DPPH), superoxide, hydroxyl radicals and on intracellular ROS, thus prevented lipid peroxidation. As result, reduced H2O2-induced death apoptosis V79-4 cells. Moreover, H2O2 the cleavage caspase-3, -9, poly-ADP-ribose polymerase (PARP) reduction Bcl-xL...
Abstract Pancreatic cancer, characterized by its late-stage diagnosis, rapid progression, and poor prognosis, represents a significant global health burden as the seventh leading cause of cancer-related mortality. Current therapeutic options are limited resistance toxicity, underscoring urgent need for novel, effective, safer treatments. In this study, we investigated anti-cancer potential Albizia julibrissin leaf extract (AJLE), prepared hot water extract, using comprehensive in vitro vivo...
Osteoarthritis (OA) is a degenerative chronic disease that affects various tissues surrounding the joints, such as subchondral bone and articular cartilage. The onset of OA associated with uncontrolled catabolic anabolic remodeling processes including cartilage bone, to adapt local biological biochemical signals. In this study, we determined whether 70% ethanolic (EtOH) extract Litsea japonica fruit (LJFE) had beneficial effects on cartilage, structural changes in tibial matrix degradation,...
Magnolia flower buds are a source of herbal medicines with various active compounds. In this study, differences in the distribution and abundance major essential oils, phenolic acids, primary metabolites between white heptapeta violet denudata var. purpurascens were characterised. A multivariate analysis revealed clear separation respect to secondary closely related metabolic systems. White contained large amounts monoterpene hydrocarbons (MH), aromatic amino monosaccharides, production...
Abstract Resistance to anthracnose or black spot ( Elsinoe ampelina ), a serious fungal pathogen in viticulture and table grape production, was investigated on 25 cultivars. Bioassays performed with culture filtrates produced by the revealed 14 resistant genotypes. In most plants resistance originated from Vitis labrucsa but also genotypes V. rupestris riparia × background showed resistance. Genetic analysis conducted F 1 , S BC developed various total, 326 were evaluated, 172 proofed be...
We cloned and sequenced the complete mitochondrial DNA (mtDNA) of three tilefishes (Branchiostegus albus, Branchiostegus argentatus, japonicus) to characterize compare their genomes (mitogenomes). The mitogenomes B. japonicus were 16,532, 16,550, 16,541 bp long, respectively, all consisted 37 genes (13 protein-coding genes, 2 ribosomal RNA, 22 transfer RNA (tRNAs)), which are typical for vertebrate mtDNA. As in other bony fishes, most encoded on H-strand, except nad6 eight tRNA that...
We determined the complete nucleotide sequence of mitochondrial genome for rabbitfish Siganus fuscescens (Perciformes, Siganidae). This genome, consisting 16,491 base pairs (bp), included 13 protein-coding genes, 2 ribosomal RNAs, 22 transfer and a noncoding control region similar those found in other vertebrates; gene order was identical to that typical vertebrates. Most genes S. were encoded on H-strand, while ND6 eight tRNA (Gln, Ala, Asn, Cys, Tyr, Ser [UCN], Glu, Pro) L-strand. The...
We obtained the complete mitochondrial genome of Ussuri white-toothed shrew Crocidura lasiura (Insectivora, Soricidae) at 17 362 base pairs (bp) containing 13 protein-coding genes, two ribosomal RNAs, 22 transfer and a non-coding control region. Its gene order is identical to that other vertebrates. Several repeat elements were identified in region (D-loop). Phylogenetic tree using mt sequences showed C. was closely related attenuata. The reports not enough study phylogenetic relationships...
Green mandarins are widely consumed unripe as mandarin oranges (Citrus unshiu Marcov.), which exhibit anti-inflammatory and anti-wrinkle effects by inhibiting the production of inflammatory cytokines matrix metalloproteinase. A randomized, double-blind, placebo-controlled clinical study was performed to verify skin improvement efficacy safety green extract (PTE). For standardization PTE, narirutin set a marker compound, PTE with constant content prepared for study. After randomizing subjects...
Current research highlights the use of natural products or phytochemicals as drugs and functional additives to treat obesity with few side effects. Sargassum horneri (SH) Ulva australis (UA) are marine waste resources on Jeju Island, Republic Korea. In this study, we analyzed their antioxidant anti-obesity efficacies confirm potential additives. We prepared SH UA extracts using 80% ethanol observed that free radical scavenging activity total phenol content were high in extracts, flavonoid...
We determined the nucleotide sequences of hypervariable D-loop region mitochondrial DNA (mtDNA) from horse bone (humerus, A.D. 700 to 800) that was excavated Kwakji archaeological site, Jeju, Korea. compared them with ones extant horses. designed three pairs oligonucleotide primers tRNA-Thr and tRNA-Phe gene regions mtDNA are highly conserved among many other animal species. cloned 232, 336, 644 bp in order determine sequence. The sequence 1,124 long; middle contained 19 tandem repeats an...
The mitochondrial genome of
The complete mitochondrial (mt) genome of the Chinese many-toothed snake, Sibynophis chinensis, was sequenced and found to be 17,163 bp in length. arrangement 13 protein-coding genes, tRNAs rRNAs identical that other common snake mt genomes. genes S. chinensis utilized ATA, ATG, ATA GTG as initiation codons AGA, AGG, TAA, TAG T termination codons. Among three tRNA clusters (LQM, WANCY HSL), LQM instead IQM, which is vertebrates. We also identified two control regions contained several...
본 연구는 제주도 해변의 벌판에서 드물게 자라는 산유자(Xylosma congesta) 잎 에탄올 추출물의 화장품 기능성 소재로서의 활용 가능성을 알아보기 위하여 cell culture model 및 invitro assay system을 이용하여 미백, 주름개선, 항염증 항산화 활성을 분석하였다. 그 결과 산유자 추출물은 B16F10 세포에 세포독성 없이 효과적으로 α-MSH에 의해 유도된 melanin 합성을 억제함으로써 높은 미백 가지는 것이 관찰되었다. CCD-986SK 세포를 주름개선 활성 능력을 procollagen 합성시험을 통해 분석한 결과, 양성 대조군으로 사용한 TGF-β 만큼은 아니지만 농도별로 각각 120, 122%의 증가시키는 것을 통하여 확인하였다. 또한 RAW 264.7 murine macrophage를 NO 생성 억제능을 분석함으로써 정도를 측정한 LPS에 생성이 농도 의존적으로 감소하는 결과를 얻을 수 있었다. DPPH 법, ABTS ORAC...