A5004493638- Sarcoma Diagnosis and Treatment
- Cutaneous Melanoma Detection and Management
- Dermatological and Skeletal Disorders
- Tumors and Oncological Cases
- Cancer and Skin Lesions
- Lymphoma Diagnosis and Treatment
- Inflammatory Myopathies and Dermatomyositis
- Urologic and reproductive health conditions
- Skin and Cellular Biology Research
- Genital Health and Disease
- Genetic and rare skin diseases.
- Cancer Diagnosis and Treatment
- Soft tissue tumor case studies
- Musculoskeletal synovial abnormalities and treatments
- Melanoma and MAPK Pathways
- Vascular Tumors and Angiosarcomas
- CNS Lymphoma Diagnosis and Treatment
- Multiple Myeloma Research and Treatments
- Soft tissue tumors and treatment
- Infectious Diseases and Mycology
- Cell Adhesion Molecules Research
- Bone Tumor Diagnosis and Treatments
- Urinary and Genital Oncology Studies
- Urological Disorders and Treatments
- Biomedical Research and Pathophysiology
Hospital General Universitario De Valencia
2013-2024
Valencia Catholic University Saint Vincent Martyr
2016-2017
In-Q-Tel
2012-2013
Sociedad Española de Medicina Interna
1995
Hospital Universitari i Politècnic La Fe
1991
Promoter methylation of tumour suppressor genes (TSGs) has recently been implicated in the pathogenesis several types cancer. Regarding melanoma, over 100 that contribute to its have identified be aberrantly hypermethylated. This is a retrospective observational study aims analyse prevalence CpG island series primary melanomas, identify associations with main clinicopathological features, and explore prognostic significance melanoma survival. DNA was analysed using methylation‐specific...
A 59-year-old man presented with a 10-cm x 8-cm tumoral plaque superficial nodule in the interscapular region of back (Fig. 1). The lesion had been growing for 25 years. As cystic was suspected, biopsied. histopathologic diagnosis low-grade sarcoma sclerosis. Two months after initial biopsy, completely excised, reaching muscular fascia, 2-cm margin and free graft. Formalin-fixed paraffin-embedded samples were submitted to histologic immunohistochemical study (4-microm paraffin sections);...
Rhabdomyosarcoma is a malignant mesenchymal neoplasm that rarely presents as primary skin tumor. So-called amianthoid fibers are hyalinized collagen mats have been described in myofibroblastic tumors but not rhabdomyosarcoma. A 65-year-old male developed submandibular nodule 9 years after an oral squamous cell carcinoma, which had treated with chemotherapy and radiotherapy. Histological examination of the revealed pleomorphic rhabdomyosarcoma extracellular deposits reminiscent so-called...
Spitz nevus is a benign melanocytic proliferation that shows relatively characteristic clinicopathologic features. Despite this, clinically confused with many other lesions, and histopathologically it sometimes difficult to distinguish from melanoma. However, rarely causes differential diagnostic problems granulomatous dermatitis. This article describes an 8‐year‐old girl who presented nodule on her right arm, clinical appearance of pyogenic granuloma. Histopathologically, there was dermal...
Journal Article Eosinophilic follicular reaction induced by Demodex folliculorum mite: a different disease from eosinophilic folliculitis Get access V. Sabater‐Marco, Sabater‐Marco Department of Pathology University General Hospital Valencia Spain Correspondence: Dr Vicente Pathology, Hospital, Avenida Tres Cruces s/n, 46014, Valencia, E‐mail: vicente.sabater@uv.es https://orcid.org/0000-0003-2607-3323 Search for other works this author on: Oxford Academic Google Scholar B. Escutia‐Muñoz,...
The occurrence of a tumor at the colostomy site after abdominoperineal resection for rectal carcinoma is rare and it may be related to previously resected or another primary tumor. We report 61‐year‐old man who developed an ulcerated skin nodule her 6 years adenocarcinoma. Histopathologically, was composed atypical large pleomorphic cells with high mitotic rate they were arranged in nests within lymphatic channels dermis. neoplastic immunoreactive cytokeratin (CK) AE1 /3, CK7, CK 34ßE12 ,...
Peripheral T‐cell lymphomas are uncommon, accounting for only 10% to 15% of all non‐Hodgkin and their classification has been controversial. We report a case peripheral lymphoma with angiocentric growth pattern which presented as paratesticular tumoral nodule in 47‐year‐old‐man. Formalin‐fixed paraffin‐embedded samples from the tumor non‐infiltrated adjacent tissue were submitted histological, immunohistochemical, polymerase chain reaction (PCR)‐based situ hybridization analysis....
Several studies have focused on identifying microRNAs involved in the pathogenesis of melanoma. However, its association with clinicopathological features has been scarcely addressed. The aim this study is to identify expression profiles related aggressive and molecular features, analyze melanoma survival. A retrospective observational was performed a series 179 formalin-fixed paraffin embedded primary cutaneous melanomas. First, screening analysis discovery set ( n = 22) using miRNA gene...
Congenital plasminogen deficiency (OMIM # 217090) is a genetic disease with recessive inheritance pattern. The formation of ligneous pseudomembranes owing to the accumulation nondegraded fibrin most frequent cutaneous manifestation.1 This usually appears in childhood, often severe manner, leading complications such as blindness, hydrocephalus, respiratory failure caused by bronchial obstruction, or even death.2 Patients who reach adulthood have history pneumonia, cervicitis, conjunctivitis,...
From the Departments of Pathology (V.S-M.) and Dermatology (A.P-F.), Valencia University General Hospital, Valencia, Spain. Address correspondence reprint requests to Dr. A. Pérez-Ferriols, Departamento de Dermatologia, Hospital Universitario, Avda. Tres Cruces s/n, 46014-Valencia,