A5079664600- Epilepsy research and treatment
- Multiple Sclerosis Research Studies
- Infectious Encephalopathies and Encephalitis
- Tuberous Sclerosis Complex Research
- Genomics and Rare Diseases
- Peripheral Neuropathies and Disorders
- Histiocytic Disorders and Treatments
- Bacterial Infections and Vaccines
- Autoimmune Neurological Disorders and Treatments
- Herpesvirus Infections and Treatments
- Retinal and Optic Conditions
- Neurological disorders and treatments
- Ocular Diseases and Behçet’s Syndrome
- Trauma Management and Diagnosis
- Genetics and Neurodevelopmental Disorders
- Neuroblastoma Research and Treatments
- Child Abuse and Related Trauma
- Attention Deficit Hyperactivity Disorder
- Genomic variations and chromosomal abnormalities
- Pharmacological Receptor Mechanisms and Effects
- Long-Term Effects of COVID-19
- Traumatic Ocular and Foreign Body Injuries
- Medical Imaging and Pathology Studies
- PI3K/AKT/mTOR signaling in cancer
Manisa Celal Bayar University
2021-2025
Selçuk Üniversitesi Tıp Fakültesi Hastanesi
2021
Sağlık Bilimleri Üniversitesi
2021
Özet Amaç: Nörokutanöz sendromlar sinir sistemini, cildi tutan hastalık grubudur. Bunların arasında en sık görülenlerden biri de tuberoskleroz’dur (TS). Bu çalışmanın amacı Celal Bayar Üniversitesi Çocuk Nörolojisi Polikliniğinde izlenen TS tanılı hastaların klinik özelliklerini değerlendirmektir. Gereç ve Yöntemler: Ocak 2005-Ocak 2023 tarihleri toplam 23 hastanın dosya kayıtları geriye dönük olarak gözden geçirildi. Bulgular : Hastaların 9’u (%39) erkek, 14’ü (%61) kızdı. 1 hastada (%0,05)...
Objectives To evaluate the demographic, clinical, laboratory, and prognostic data of children with acute disseminated encephalomyelitis respect to anti-myelin oligodendrocyte glycoprotein (MOG) antibody status. Methods Acute patients (n = 245) from 24 centers followed up between 2010 2022 were evaluated retrospectively. The short- long-term outcome characteristics (disease severity course, clinical relapse, recovery rates) assessed. Incomplete was defined as modified Rankin Score ≥1 or...
Abstract Objective The objective of this study was to examine the serum levels vasoactive neuropeptides (calcitonin gene‐related peptide [CGRP], pituitary adenylate cyclase‐activating peptide‐38 [PACAP‐38], substance P [SP], and intestinal [VIP], which have been linked pathophysiology migraine in adults) pediatric without aura during both pain attacks pain‐free periods a control group, with view evaluating their diagnostic value migraine. Background diagnosis is based on clinical features...
Objective: Optic neuritis (ON) is a condition that causes vision loss usually in one eye, often due to multiple sclerosis (MS).In this study, we aim examine the clinical course, diagnostic tests, and treatment outcomes of patients presenting with acute or subacute ON. Method:In retrospective examined medical records pediatric aged 3-18 years who were evaluated for ON our neurology department between January 2015 2021. Results:Our study population 18 participants consisted female (55.6%),...
As with many genetic diseases, the diagnostic role of next-generation sequencing is invaluable for early-onset epileptic encephalopathies. SNARE proteins in synaptic vesicles (synaptobrevin-2) and plasma membrane (syntaxin-1, SNAP-25) are involved exocytosis recycling.
Çocuklarda inme beyin tümörleri kadar sıktır ve çocukluk çağında ilk on ölüm nedeni arasındadır. Kafa travması geçiren çocuklarda, hemorojik inme, iskemik inmeye göre daha sık görülmektedir. Hafif kafa sonrası 2 yaş altı çocuklarda beynin anatomik özellikleri mekanik vazospazm gibi mekanizmalarla açıklanmaya çalışılan lentikülostriat bildirilmektedir. Aileler hekimler tarafından çoğunlukla önemsenmeyen hafif travmaların her zaman masum olmadığını dikkat çekmek amacıyla acil servisimize...
Objective: Treatment of childhood refractory epilepsy is a challenge for clinicians. Lacosamide new generation antiepileptic drug which being used focal onset seizures adults and children. Efficacy safety the have been demonstrated in various studies. The aim this retrospective cross-sectional study to evaluate efficacy lacosamide our clinic. Methods: We examined medical records 14 patients treated with clinic between January 2016 2020 terms demographic, etiological, neuroimaging findings,...
Epileptik ensefalopatiler (EE), çoklu nöbet tipleri, gelişimsel gecikme ve hatta gerileme ile karakterize ciddi epilepsi sendromlarıdır. CHD2'deki (kromodomain sarmal DNA bağlayıcı protein 2) patojenik varyantlar, epileptik ensefalopatilerde ayrıca zihinsel engellilikten atonik-miyoklonik epilepsiye kadar değişen fenotipik değişkenlik spektrumuna sahip nörogelişimsel bozukluklarda bildirilmiştir. Biz bu olgu sunumunda oğul, erkek kardeş anneden oluşan kalıtsal bir CHD2 varyantı ailesini...