A5016221728- Spinal Fractures and Fixation Techniques
- Scoliosis diagnosis and treatment
- Spine and Intervertebral Disc Pathology
- Cervical and Thoracic Myelopathy
- Medical Imaging and Analysis
- Pelvic and Acetabular Injuries
- Management of metastatic bone disease
- Frailty in Older Adults
- Musculoskeletal pain and rehabilitation
- Cardiac, Anesthesia and Surgical Outcomes
- Spinal Hematomas and Complications
- Bone Tumor Diagnosis and Treatments
- Orthopaedic implants and arthroplasty
- Nutrition and Health in Aging
- Parkinson's Disease and Spinal Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Hip and Femur Fractures
- Hip disorders and treatments
- Sarcoma Diagnosis and Treatment
- Meningioma and schwannoma management
- Topological Materials and Phenomena
- Colorectal Cancer Surgical Treatments
- Neurofibromatosis and Schwannoma Cases
- Oral and Maxillofacial Pathology
- Intraoperative Neuromonitoring and Anesthetic Effects
University of California, San Francisco
2016-2025
Neurological Surgery
2016-2025
Hospital for Special Surgery
2015-2024
University of California System
2006-2024
City College of San Francisco
2024
University of California San Francisco Medical Center
2013-2023
Columbia University
2015-2023
University of Calgary
2016-2023
University of Virginia
2008-2023
Johns Hopkins University
2015-2023
In Brief Study Design. Prospective multicenter study evaluating operative (OP) versus nonoperative (NONOP) treatment for adult spinal deformity (ASD). Objective. Evaluate correlations between spinopelvic parameters and health-related quality of life (HRQOL) scores in patients with ASD. Summary Background Data. Sagittal is commonly defined by an increased sagittal vertical axis (SVA); however, SVA alone may underestimate the severity deformity. Spinopelvic provide a more complete assessment...
Positive spinal regional and global sagittal malalignment has been repeatedly shown to correlate with pain disability in thoracolumbar fusion.To evaluate the relationship between cervical alignment postoperative outcomes for patients receiving multilevel posterior fusion.From 2006 2010, 113 received fusion stenosis, myelopathy, kyphosis. Radiographic measurements made at intermediate follow-up included following: (1) C1-C2 lordosis, (2) C2-C7 (3) vertical axis (C2-C7 SVA; distance C2 plumb...
Positive spinal regional and global sagittal malalignment has been repeatedly shown to correlate with pain disability in thoracolumbar fusion.To evaluate the relationship between cervical alignment postoperative outcomes for patients receiving multilevel posterior fusion.From 2006 2010, 113 received fusion stenosis, myelopathy, kyphosis. Radiographic measurements made at intermediate follow-up included following: (1) C1-C2 lordosis, (2) C2-C7 (3) vertical axis (C2-C7 SVA; distance C2 plumb...
BACKGROUND: Global sagittal malalignment is significantly correlated with health-related quality-of-life scores in the setting of spinal deformity. In order to address rigid deformity patterns, use osteotomies has seen a substantial increase. Unfortunately, variations established techniques and hybrid combinations have made comparisons outcomes difficult. OBJECTIVE: To propose classification system anatomically-based provide common language among spine specialists. METHODS: The proposed...
BACKGROUND: The SRS-Schwab classification of adult spinal deformity (ASD) is a validated system that provides common language for the complex pathology ASD. Classification reliability has been reported; however, correlation with treatment not assessed. OBJECTIVE: To assess clinical relevance based on correlations health-related quality life (HRQOL) measures and decision to pursue operative vs nonoperative treatment. METHODS: Prospective analysis consecutive ASD patients (18 years age older)...
Retrospective review of prospective, multicenter database.The aim the study was to determine age-specific spino-pelvic parameters, extrapolate Oswestry Disability Index (ODI) values from published Short Form (SF)-36 Physical Component Score (PCS) data, and propose realignment thresholds for adult spinal deformity (ASD).The Scoliosis Research Society-Schwab classification offers a framework defining alignment in patients with ASD. Although changes patient-reported outcomes have been...
Retrospective review of a multicenter database.To determine the complication rates associated with surgical treatment pediatric scoliosis and to assess variables increased rates.Wide variability is reported for complications operative scoliosis. Limited number patients, surgeons, diagnoses occur in most reports. The Scoliosis Research Society Morbidity Mortality (M&M) database aggregates deidentified data, permitting determination from large numbers patients surgeons.Cases (age ≤18 years),...
Background: Adult spinal deformity is a prevalent cause of pain and disability. Established measures sagittal spinopelvic alignment such as vertical axis pelvic tilt can be modified by postural compensation, including retroversion, knee flexion, the use assistive devices for standing. We introduce T1 angle, novel measure that simultaneously accounts both inclination retroversion. The purpose this study was to investigate relationship angle other established correlate these parameters with...
Abstract The Josephson effect describes the generic appearance of a supercurrent in weak link between two superconductors. Its exact physical nature deeply influences properties supercurrent. In recent years, considerable efforts have focused on coupling superconductors to surface states three-dimensional topological insulator. such material, an unconventional induced p -wave superconductivity should occur, with doublet topologically protected gapless Andreev bound states, whose energies...
OBJECTIVE Although multiple reports have documented significant benefit from surgical treatment of adult spinal deformity (ASD), these procedures can high complication rates. Previously reported complications rates associated with ASD surgery are limited by retrospective design, single-surgeon or single-center cohorts, lack rigorous data on complications, and/or follow-up. Accurate definition is important and may serve as a resource for patient counseling efforts to improve the safety care....
A retrospective study.To assess the mechanisms and independent risk factors associated with proximal junctional kyphosis (PJK) in patients treated surgically for adult spinal deformity long fusions to sacrum.The occurrence of PJK may be related preoperative postoperative sagittal parameters. The adults are not well defined.Consecutive who underwent instrumented fusion surgery (≥6 vertebrae) sacrum a minimum 2 years follow-up were retrospectively studied. Risk included patient factors,...
In Brief Study Design. Multicenter, prospective, consecutive series. Objective. To evaluate responsiveness of the Scoliosis Research Society (SRS)-Schwab adult spinal deformity (ASD) classification to changes in health-related quality life (HRQOL) after treatment for ASD. Summary Background Data. Ideally, a system should describe and be responsive disease state. We hypothesized that SRS-Schwab is HRQOL measures Methods. A multicenter, series from International Spine Group. Inclusion...
Multicenter, retrospective series.To analyze the incidence, mode, and location of acute proximal junctional failures (APJFs) after surgical treatment adult spinal deformity.Early above deformity constructs are a serious clinical problem; however, incidence nature early APJFs remain unclear.A total 1218 consecutive surgeries across 10 centers were retrospectively reviewed to evaluate APJF, defined as any following within 28 weeks index procedure: minimum 15° post-operative increase in...
Retrospective review of a prospectively collected, multicenter database.To assess rates new neurologic deficit (NND) associated with spine surgery.NND is potential complication surgery, but previously reported are often limited by small sample size and single-surgeon experiences.The Scoliosis Research Society morbidity mortality database was queried for spinal surgery cases complicated NND from 2004 to 2007, including nerve root (NRD), cauda equina (CED), cord (SCD). Use neuromonitoring...
A retrospective analysis of a prospective, multicenter database.The aim this study was to evaluate the health impact symptomatic adult spinal deformity (SASD) by comparing Standard Form Version 2 (SF-36) scores for SASD with United States normative and chronic disease values.Recent data have identified radiographic parameters correlating poor health-related quality life SASD. Disability comparisons between patients diseases may provide further insight burden caused SASD.Consecutive patients,...
Despite the complexity of cervical spine deformity (CSD) and its significant impact on patient quality life, there exists no comprehensive classification system. The objective this study was to develop a novel system based modified Delphi approach characterize intra- interobserver reliability classification.Based an extensive literature review with expert panel, CSD generated. included descriptor 5 modifiers that incorporated sagittal, regional, global spinopelvic alignment neurological...
Study Design. Retrospective cohort. Objective. To explore proximal junctional kyphosis (PJK) as a function of age-adjusted surgical correction goals. Summary Background Data. Recent adult spinal deformity (ASD) studies show that alignment targets are age-specific. Despite recognizing age and malalignment PJK risk factors, no study has assessed the age-specific effects on PJK. Methods. ASD patients with fusions to pelvis were included stratified into three groups: young adults (YA <40 years...
Improved understanding of rod fracture (RF) in adult spinal deformity could be valuable for implant design, surgical planning, and patient counseling.To evaluate symptomatic RF after posterior instrumented fusion deformity.A multicenter, retrospective review was performed. Inclusion criteria were deformity, age older than 18 years, more 5 levels fusion. Rod failures divided into early (≤12 months) late (>12 months).Of 442 patients, 6.8% had RF. rates 8.6% titanium alloy, 7.4% stainless...
Improved understanding of rod fracture (RF) following adult spinal deformity (ASD) surgery could prove valuable for surgical planning, patient counseling, and implant design. The objective this study was to prospectively assess the rates risk factors RF ASD.This a prospective, multicenter, consecutive series. Inclusion criteria were ASD, age > 18 years, ≥5 levels posterior instrumented fusion, baseline full-length standing spine radiographs, either development or radiographs obtained at...
Study Design. Retrospective review of a prospective multicenter database evaluating surgical adult spinal deformity (ASD) patients. Objective. This study aims to identify risk factors for medical complications in ASD patients undergoing surgery. Summary Background Data. surgery is known its high complication rate. examines baseline patient characteristics predictors Methods. Intra and perioperative were included. Medical were: infection, pneumonia, urinary tract c-difficile, sepsis, stroke,...