A5010690171- Bone health and osteoporosis research
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Orthopaedic implants and arthroplasty
- Bone fractures and treatments
- Bone Tissue Engineering Materials
- Bone Metabolism and Diseases
- Foot and Ankle Surgery
- Bioinformatics and Genomic Networks
- Scoliosis diagnosis and treatment
- Orthopedic Surgery and Rehabilitation
- biodegradable polymer synthesis and properties
Soochow University
2019-2024
First Affiliated Hospital of Soochow University
2019-2024
Polyurethane (PU) and polyurea (PUA) materials have shown significant potential for application in tissue repair. Herein, we design a glycerol ethoxylate (PEG)-based poly(urethane-urea) bone The polymer precursor was prepared from the reaction of PEG isophorone diisocyanate (IPDI). cystine dimethyl ester used as cross-linker preparation elastomers. material further strengthened by physical blending nano-hydroxyapatite (nHA). biological properties final were evaluated mechanical testing,...
Objective In the treatment of lumbar degenerative spondylolisthesis (LDS) with Posterior interbody fusion (PLIF) surgery, implants play a key role in supporting vertebral body and facilitating fusion. The objective this study was to assess impact implantation depth on sagittal parameters functional outcomes patients undergoing PLIF surgery. Methods This reviewed 128 L4‐L5 LDS between January 2016 August 2019. All underwent an open surgery that included intravertebral decompression, pedicle...
Abstract Osteoporosis is a major health concern worldwide. The present study aimed to identify effective biomarkers for osteoporosis detection. In osteoporosis, 559 differentially expressed genes (DEGs) were enriched in PI3K-Akt signaling pathway and Foxo pathway. Weighted gene co-expression network analysis showed that green, pink, tan modules clinically significant modules, six (VEGFA, DDX5, SOD2, HNRNPD, EIF5B, HSP90B1) identified as “real” hub the protein–protein interaction network,...
To evaluate the therapeutic effects of applying internal fixation with a T-shaped locking plate that was used on distal radius in fractures anterior process calcaneus (APC) calcaneocuboid (CC) joint injury.This retrospective study enrolled adult patients diagnosed APC CC injury had received radius. Group NA underwent open reduction 'not-across' fixation; and group A 'across' fixation. The outcomes were assessed using American Orthopaedic Foot Ankle Society (AOFAS) score, visual analogue...