Jitander K. Kapoor

ORCID: 0000-0003-2664-1538
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Research Areas
  • Synthesis and Reactions of Organic Compounds
  • Synthesis and Characterization of Heterocyclic Compounds
  • Synthesis and biological activity
  • Metal complexes synthesis and properties
  • Electrochemical Analysis and Applications
  • Inorganic and Organometallic Chemistry
  • Synthesis and Reactivity of Heterocycles
  • Synthesis and Biological Evaluation
  • Synthesis and Catalytic Reactions
  • Multicomponent Synthesis of Heterocycles
  • Water Quality and Pollution Assessment
  • Electrohydrodynamics and Fluid Dynamics
  • Quinazolinone synthesis and applications
  • Sulfur-Based Synthesis Techniques
  • Analytical chemistry methods development
  • Inflammatory mediators and NSAID effects
  • Analytical Chemistry and Sensors
  • Water Quality Monitoring and Analysis
  • Ferrocene Chemistry and Applications
  • Synthesis and pharmacology of benzodiazepine derivatives
  • Coagulation and Flocculation Studies
  • Synthesis of Organic Compounds
  • Cancer therapeutics and mechanisms
  • Environmental Chemistry and Analysis
  • Water Quality Monitoring Technologies

National Institute of Technology Kurukshetra
2011-2024

Kurukshetra University
1993-2013

A solvent-free green synthesis of N-sulfonylformamidines is reported via the direct condensation N,N-dimethylformamide dimethyl acetal (DMF-DMA) and sulfonamide derivatives at room temperature. The described method avoids use metal catalysts as well hazardous solvents, which are not permitted for pharmaceutical manufacture, reactions or isolation products. Hence, current work presents a fast efficient alternative to earlier methods. mild nature procedure demonstrated by varied functional...

10.1039/c3gc40797g article EN Green Chemistry 2013-01-01

Cancer persists as a principal cause of global mortality. Despite significant progress in cancer therapeutics recent decades, chemotherapy remains primary modality for treatment. Based on their mechanism...

10.1039/d5dt00993f article EN Dalton Transactions 2025-01-01

A series of pyrazolylbenzyltriazoles as celecoxib analogues having a 1,5-diaryl relationship potential leads for the development molecular probes imaging COX-2 expression was prepared by reaction appropriate trifluoromethyl-β-diketones (12a–12i) with 1-[(4-hydrazinophen-1-yl)methyl]-1H-1,2,4-triazole hydrochloride in refluxing ethanol. All compounds were screened vitro cyclooxygenase (COX) assays to determine COX-1 and inhibitory potency. Moreover, anti-inflammatory activity selected...

10.1039/c4nj00226a article EN New Journal of Chemistry 2014-05-22

A new spectrophotometric method has been developed for determination of molybdenum using surfactant-mediated liquid--liquid extraction. Molybdenum(V) obtained by ascorbic acid reduction in 2.5 M H_2SO_4 reacted spontaneously with thiocyanate and cetyl trimethyl ammonium bromide (CTAB), forming an intense orange yellow complex that was extracted quantitatively into 1,2-dichloroethane absorbed at 460 nm. The absorbance the extract found to be stable more than 24 h. Beer's law obeyed over...

10.3906/kim-1302-33 article EN TURKISH JOURNAL OF CHEMISTRY 2014-01-01

ABSTRACT This study explores the potential of newly synthesized macrocyclic Schiff base metal complexes containing Zn(II), Cu(II), Ni(II) and Co(II) ions as Topoisomerase IIβ inhibitors. The were derived from condensation 2,3‐diamino‐5‐bromopyridine 2,5‐thiophenedicarboxaldehyde. Their formation was confirmed through various spectroscopic techniques. To gain insights into their structure biological activity, computational modeling employed. density functional theory (DFT) utilized to...

10.1002/aoc.7885 article EN Applied Organometallic Chemistry 2024-11-20

Reaction of heterocyclylhydrazines (la-f) with 3-ethoxymethylenepentane-2,4-dione (2) and ethyl 2-ethoxymethylene-3-oxobutyrate (3) yields exclusively 4-acetyl-5-methyl-1heterocyclylpyrazoles (4a-f) 4-carbethoxy-5-methyl-l-heterocyclylpyrazoles (5a-f), respectively, in good yields.

10.1515/hc.2001.7.1.49 article cc-by-nc-nd Heterocyclic Communications 2001-01-01

A selective synthesis of 3‐(α,α‐dibromoacetyl)‐4‐hydroxy‐6‐methyl‐2 H ‐pyran‐2‐one ( 3 ) has been achieved by bromination DHA using CuBr 2 /CHCl ‐EtOAc. The reaction with different thioureas/thiomides/thiosemicarbazide offers a convenient and efficient method for the syntheses 2‐substituted 4‐(4‐hydroxy‐6‐methyl‐2 ‐2‐oxopyran‐3‐yl)thiazoles. These thiazoles were evaluated their antimicrobial antifungal activity.

10.1002/jhet.3116 article EN Journal of Heterocyclic Chemistry 2018-02-07

An extractive spectrophotometric method has been developed for microdetermination of molybdenum. At room temperature Mo(VI) was reduced to Mo(V) in 2 M H SO 4 using ascorbic acid as a reductant. The formed yellow‐coloured (1 : 2) complex with 6‐chloro‐3‐hydroxy‐2‐(3 ′ ‐hydroxyphenyl)‐4‐oxo‐4H‐1‐benzopyran (CHHB). quantitatively extracted into toluene and absorbed maximum at λ max 404 nm. Beer’s law obeyed over the concentration range 2.31 μ g Mo ml −1 molar absorptivity Sandell′s sensitivity...

10.1155/2013/420768 article EN cc-by Journal of Chemistry 2012-08-28

A series of novel derivatives 1,3-oxazolidin-2-one 12a-12n has been synthesized starting from 4-nitro-(L)- phenylalanine by involving five-step reaction sequence. All the compounds were screened for their in vitro antibacterial activity against four pathogenic bacterial strains namely, Staphylococcus aureus, Bacillus subtilis (Gram-positive), Escherichia coli, Pseudomonas aeruginosa (Gram-negative) and antifungal two fungal Candida albicans Saccharomyces cerevisiae. showed Gram-positive...

10.2174/15680266113139990132 article EN Current Topics in Medicinal Chemistry 2013-09-01

Praseodymium(III) ion selective electrodes have been prepared using N-N᾽o ‐phenylene‐bis(salicylideneimine) as a suitable electro‐active material. Several membranes comprising of varying compositions material with epoxy resin and polyvinylchloride (PVC) binding materials were prepared. However the one composition 50% Schiff᾽s base binder was found to exhibit best performance. The sensor presents linear dynamic range 1.0×10 -6 -1 M Nernstian slope 19.9 mV/decade. has quick response time....

10.1155/2011/358039 article EN cc-by Journal of Chemistry 2011-01-01

Abstract An efficient and practically feasible synthesis of a series novelpyrazole‐clubbed piperazinyl urea derivatives screening results their antimicrobial activity along with current‐voltage studies selected compounds were reported. The reaction (1,3‐diaryl‐1 H ‐pyrazol‐4‐yl)(piperazin‐1‐yl)methanone hydrochlorides various cycloalkyl/aryl isocyanates under basic condition afforded the formation target in good to excellent yield. intermediate 8a,b synthesized several steps by method...

10.1002/slct.202204419 article EN ChemistrySelect 2023-01-10

<title>Abstract</title> This study investigates the basic characteristics of various surface water sources, including pond water, river and canal across four distinct seasons. The research endeavours to assess impact a cationic polyelectrolyte, specifically poly diallyl dimethyl ammonium chloride (PDADMAC), utilized as coagulation aid in conjunction with lime for treatment purposes. Employing conventional jar test apparatus, turbidity removal from diverse samples is examined. Furthermore,...

10.21203/rs.3.rs-4150081/v1 preprint EN cc-by Research Square (Research Square) 2024-04-25

Abstract Reaction of several hydrazinobenzoquinolines with 1,3-diketones affords pyrazolylbenzoquinolines rather than the reported benzodiazepinoquinolines. The structural assignment is based upon NMR (1H and 13C) spectral data an unambiguous synthesis.

10.1246/bcsj.66.1703 article EN Bulletin of the Chemical Society of Japan 1993-06-01

Abstract Reaction of 1-(5-hydroxy-3-methyl-1-substituted-4-pyrazolyl)-1,3-butanediones (1a-d) with 1-hydrazinophthalazine hydrochloride leads to the formation 4-acetyl-5-hydroxy-3-methyl-1-substitutedpyrazoles (3a-d) along 3-methyl-s-triazolo[3,4-a]phthalazine (4) in good yields.

10.1080/00397919408010577 article EN Synthetic Communications 1994-10-01
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