A5025509868- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- RNA Interference and Gene Delivery
- Aquaculture disease management and microbiota
- Bee Products Chemical Analysis
- Essential Oils and Antimicrobial Activity
- Tea Polyphenols and Effects
- Curcumin's Biomedical Applications
- Drug-Induced Hepatotoxicity and Protection
- Sperm and Testicular Function
- Traditional Chinese Medicine Analysis
- Polysaccharides Composition and Applications
- Phytochemicals and Antioxidant Activities
- Cancer Research and Treatment
- Medicinal Plants and Neuroprotection
- Pancreatitis Pathology and Treatment
- Reproductive biology and impacts on aquatic species
- Nanoparticles: synthesis and applications
- Advanced Nanomaterials in Catalysis
- Inflammatory Bowel Disease
- Reproductive Biology and Fertility
- Biological Research and Disease Studies
- Skin Protection and Aging
Manipal Academy of Higher Education
2014-2017
The present work attempts to develop and statistically optimize transfersomes containing EGCG hyaluronic acid synergize the UV radiation-protective ability of both compounds, along with imparting antioxidant anti-aging effects. Transfersomes were prepared by thin film hydration technique, using soy phosphatidylcholine sodium cholate, combined high-pressure homogenization. They characterized respect size, polydispersity index, zeta potential, morphology, entrapment efficiency, Fourier...
Aeromonas hydrophila is a Gram-negative bacterium that causes high mortality in different fish species and at growth stages. Although vaccination has significantly contributed to the decline of disease outbreaks aquaculture, use oral vaccines lagged behind injectable due lack proven efficacy, being from primary immunization or by boost protocols. In this study, outer membrane protein W (OmpW) A. was cloned, purified, encapsulated poly d,l-lactide-co-glycolic acid (PLGA) nanoparticles (NPs)...
Context: Asenapine maleate (ASPM) is an antipsychotic drug for the treatment of schizophrenia and bipolar disorder. Extensive metabolism makes oral route inconvenient ASPM.Objective: The objective this study to increase ASPM bioavailability via transdermal by improving skin permeation using combined strategy chemical nano-carrier (transfersomal) based approaches.Materials methods: Transfersomes were prepared thin film hydration method soy-phosphatidylcholine (SPC) sodium deoxycholate (SDC)....
The use of oral vaccination in finfish has lagged behind injectable vaccines for a long time as fall short injection conferring protective immunity. Biodegradable polymeric nanoparticles (NPs) have shown potential to serve antigen delivery systems vaccines. In this study the recombinant outer membrane protein A (rOmpA) Edwardsiella tarda was encapsulated chitosan NPs (NP-rOmpA) and used Labeo fimbriatus. rOmpA purity 85%, nanodiameter <500 nm, encapsulation efficiency 60.6%, zeta +19.05 mV,...
Cryopreservation of spermatozoa plays a significant role in reproductive medicine and fertility preservation. Chicken egg yolk is used as an extender cryopreservation human using glycerol citrate (GEYC) buffered medium. Even though 50% survival generally achieved with this method, the risk high levels endotoxins transmission pathogens from chicken matter concern. In present study we attempted to establish chemically defined medium which can replace without affecting sperm survival....
The effects of permeation enhancers and sonophoresis on the transdermal lercanidipine hydrochloride (LRDP) across mouse skin were investigated. Parameters including drug solubility, partition coefficient, degradation in determined. Tween-20, dimethyl formamide, propylene glycol, poly ethylene glycol (5% v/v) different concentration ethanol used for enhancement. Low frequency ultrasound was also applied presence absence to assess its effect augmenting drug. All enhancers, except increased...
ABSTRACT:Epigallocatechin-3-gallate (EGCG) is a potent antioxidant and free radical scavenger present in green tea. It extensively used as antioxidant, immunomodulator, anticancer, neuroprotective, cardioprotective, antiviral,antibacterial, photo protective anti aging agent. The objective of the work was to develop validate an RP-HPLC method for determination EGCG lipid based nanoformulations. analysis performed by isocratic elution using Phenomenex C18 column (4.6 × 250 mm, 5 µm) at 25 °C....