A5052385927- Ocular Oncology and Treatments
- Retinal Diseases and Treatments
- Retinal and Macular Surgery
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Retinal Development and Disorders
- Ocular Diseases and Behçet’s Syndrome
- Corneal Surgery and Treatments
- Retinal Imaging and Analysis
- Intraocular Surgery and Lenses
- Ocular Infections and Treatments
- CNS Lymphoma Diagnosis and Treatment
- Vascular Tumors and Angiosarcomas
- Cutaneous Melanoma Detection and Management
- Toxoplasma gondii Research Studies
- Sarcoidosis and Beryllium Toxicity Research
- Otitis Media and Relapsing Polychondritis
- Historical Psychiatry and Medical Practices
- Photodynamic Therapy Research Studies
- melanin and skin pigmentation
- Burn Injury Management and Outcomes
- Soft tissue tumor case studies
- Child Abuse and Related Trauma
- Nonmelanoma Skin Cancer Studies
- Melanoma and MAPK Pathways
Tennessee Retina
2016-2025
Insight (China)
2024
Retina Associates
2019
Medical College of Wisconsin
2013-2014
Thomas Jefferson University
2012-2013
Wills Eye Hospital
2011-2013
Vanderbilt University Medical Center
2010
Vanderbilt University
2009-2010
New York Eye and Ear Infirmary
2007
Icahn School of Medicine at Mount Sinai
2005-2006
PURPOSEValidated and accurate prognostic testing is critical for precision medicine in uveal melanoma (UM). Our aims were to (1) prospectively validate an integrated classifier combining a 15-gene expression profile (15-GEP)
Abstract Purpose: With a prevalence of approximately 5% in the U.S., uveal melanocytic tumors indeterminate malignant potential (UMTIMP) are primarily managed by observation for growth prior to treatment. While these lesions can be assessed intraocular tumor biopsy and genetic testing, serial operating room is not feasible routine management UMTIMPs. On other hand, aqueous humor (AH) from anterior chamber eye easily safely obtained an office-based procedure that repeated periodically....
9590 Background: Uveal melanocytic tumors of indeterminate malignant potential (UMTIMP) are usually managed by a “watch and wait” approach before the decision to treat. Although aggressiveness these lesions can be assessed tumor-biopsy based molecular testing, serial tumor biopsies may impractical not always feasible for routine clinical management UMTIMPs. In contrast, aqueous humor (AH) sampling safely performed as an outpatient procedure is repeatable. AH protein biomarkers strongly...
Herein we present a case of giant cell arteritis presenting with nodular posterior scleritis and exudative retinal detachment mimicking choroidal mass.A 67-year-old man presented sudden onset left-sided periorbital pain, blurry vision, lesion in the pole. Despite treatment high-dose oral prednisone for suspected mass, vision his left eye did not recover, he developed optic nerve pallor on exam. Further evaluation revealed an ESR >140 mm/hr (Upper limit normal = 20 mm/hr), CRP 113 mg/L 9...
Auto-enucleation is a sign of untreated psychosis. We describe two patients who presented with attempted auto-enucleation while being incarcerated. This an observation two-case series young men suffered psychosis These showed severe self-inflicted ocular trauma during episodes Injuries included orbital bone fracture and dehiscence the lateral rectus in one patient retinal hemorrhage partial optic nerve avulsion second patient. symptom urgent finding can occur jail setting which psychiatric...
Importance Biosimilars may be lower-cost alternatives to originator biologic products, potentially offering expanded access or reduced economic burden, but have not been evaluated with aflibercept in diabetic macular edema (DME). Objective To compare efficacy and safety of MYL-1701P, an biosimilar, reference (Eylea [Regeneron]) DME. Design, Setting, Participants This was a double-masked, randomized clinical trial that included participants at 77 centers across the US, Europe, Japan, India....
To assess the safety and efficacy of biweekly (every 2 weeks) intravitreal aflibercept injections (IAI) mg in eyes with refractory neovascular age-related macular degeneration (NVAMD).A prospective, single-arm, interventional study was conducted. Eyes NVAMD received six IAIs through week 12, followed by a 4-week treatment pause until 16. residual subretinal fluid (SRF) at 16 were randomized 1:1 to either four additional or (q4W) IAI dosing 24. All subsequently treated q4W 52.Enrolled (n =...
To describe a patient with an amelanotic choroidal melanoma, originally misdiagnosed as granuloma, following his systemic diagnosis of tattoo-associated sarcoidosis.The tumor, suspected to be failed initial steroid treatment. Full-thickness chorioretinal biopsy demonstrated histologic presence uveal melanoma and tumor genetics via GEP analysis PRAME negative, Class 1A lesion. The was treated successfully I-125 plaque brachytherapy.Despite which predisposes melanomas can still occur should...
To describe a patient with bilateral retinal arteriolar occlusions secondary to talc in the associated vessels resulting from intravenous drug use and patent foramen ovale.A 24-year-old woman presented visible foreign material vessels. A transesophageal echocardiogram showed ovale. subsequent chest computed tomography angiogram diffuse fine nodular pattern focal nodules bilaterally lung biopsy body giant cell reaction polarizable consistent talc. This patient's ovale allowed larger particles...
BACKGROUND AND OBJECTIVE: To evaluate the safety and efficacy of a blunt sub-Tenon's cannula for local anesthesia before vitreoretinal surgery compared to sharp retrobulbar needle. PATIENTS METHODS: Retrospective, comparative study all patients undergoing at Medical College Wisconsin between August 2009 November 2013. Institutional review board approval was obtained. RESULTS: Of 940 surgeries performed with cannula, 99% (938 940) were completed. 771 needle, (770 771) Factors associated use...