A5101612005- Medical Research and Treatments
- Multiple and Secondary Primary Cancers
- Cancer, Lipids, and Metabolism
- Global Cancer Incidence and Screening
- Cancer-related gene regulation
- Body Contouring and Surgery
- Cancer, Hypoxia, and Metabolism
- Chronic Kidney Disease and Diabetes
- Acupuncture Treatment Research Studies
- Esophageal Cancer Research and Treatment
- Lymphatic System and Diseases
- Diagnosis and Treatment of Venous Diseases
- Peroxisome Proliferator-Activated Receptors
- Reconstructive Surgery and Microvascular Techniques
- Breast Cancer Treatment Studies
- Cancer Research and Treatments
- Cancer Risks and Factors
- Cancer Mechanisms and Therapy
- TGF-β signaling in diseases
- Bioactive natural compounds
- Cancer Treatment and Pharmacology
- ATP Synthase and ATPases Research
- Cancer Genomics and Diagnostics
- Fibroblast Growth Factor Research
- Ginseng Biological Effects and Applications
Guangxi Medical University
2020-2024
Tumor Hospital of Guangxi Medical University
2016-2021
Southern Medical University
2008-2020
Gene Tech (China)
2020
Guangdong Medical College
2020
Integrated Chinese Medicine (China)
2019
Breast Center
2016
RhoE/Rnd3 is an atypical member of the Rho superfamily proteins, However, global biological function profile this protein remains unsolved. In present study, a RhoE‑knockout H9C2 cardiomyocyte cell line was established using CRISPR/Cas9 technology, following which differentially expressed genes (DEGs) between knockout and wild‑type lines were screened whole genome expression gene chips. A total 829 DEGs, including 417 upregulated 412 downregulated, identified threshold fold changes ≥1.2...
In the present study, we examined molecular mechanism of astragaloside IV (AS-IV) in high glucose (HG)-induced epithelial-to-mesenchymal transition (EMT) renal proximal tubular epithelial cells (PTCs). NRK-52E cell viability and apoptosis were determined by counting kit-8 (CCK-8) assay flow cytometric analysis, respectively. Expressions E-cadherin, N-cadherin, vimentin, occludin measured Western blot, those E-cadherin N-cadherin additionally immunofluorescence analysis. Transforming growth...
Abstract Doxorubicin (DOX) is one of the most effective chemotherapy drugs for treatment metastatic breast cancer (BC), but drug resistance becomes an obstacle to treatment. This study aims investigate role Ribosomal S6 protein kinase 4 (RSK4) in regulating BC DOX. We first used Kaplan–Meier Plotter identify prognostic roles RSK4 BC. DOX-resistant cells (MCF-7/DOX) were constructed and expression was determined by reverse transcript polymerase chain reaction western blot. Subsequently, we...
Objectives: This study is aimed to investigate the role of androgen receptor (AR) in regulating oral squamous cell carcinoma (OSCC) cells migration. Materials and methods: Tumors from 23 patients with OSCC five lines were used for analyzing AR expression. The effects agonist antagonist examine migration cells. Results: Ten tumors positive. There was no significant difference total EGFR (tEGFR) expression between AR-positive AR-negative tumors. However, phosphorylated (pEGFR) significantly...
Aquaporin 1 (AQP1) contributes to the progression of several cancer types, but its potential involvement in triple‑negative breast (TNBC) is unclear. The aim present study was examine role AQP1 cell proliferation and invasion TNBC. Reverse transcription‑quantitative PCR analysis western blotting were used detect expression different lines. A short hairpin (sh)RNA targeting established transfected into MDA‑MB‑231 cells. To investigate effects knockdown, proliferation, migration evaluated by...
Abstract The beneficial function of gastrodin towards many inflammatory diseases has been identified. This study designed to see the influence in a cell model chronic obstructive pulmonary disease (COPD). MRC‐5 cells were treated by LPS, before which was administrated. effects evaluated conducting CCK‐8, FITC‐PI double staining, Western blot, qRT‐PCR and ELISA. Besides this, downstream effector signalling studied decode how exerted its function. And dual‐luciferase assay used detect...
The aim of this study was to compare the effectiveness and toxicity neoadjuvant chemotherapy regimens, xeloda/epirubicin/cyclophosphamide (XEC) vs 5-fluorouracil/epirubicin/cyclophosphamide (FEC), followed by adjuvant capecitabine/taxotere (XT) taxotere (T), in axillary lymph node (LN)-positive early-stage breast cancer. In randomized, Phase III trial, 137 patients with operable primary cancer (T2-0, N0-1) who were tested LN positive through aspiration biopsy LNs randomized (1:1) four...
To observe the curative effect of Bo's abdominal acupuncture on chronic fatigue syndrome (CFS).Forty cases with CFS were treated by at points for conducting qi back to its origin and 4 abdomen once a day 2 weeks. Scores symptoms scores questionnaires compared before after treatment.After treatment, clinical patients differently alleviated, symptoms, mental condition neural feeling in obviously reduced (P<0.01-0.05).Bo's has good general disease complex especially lassitude, anorexia,...
Gynecologic cancers have become a major threat to women's health. The molecular biology of gynecologic is not as well understood that breast cancer, and precision targeting still new. Although viewed collectively group within the female reproductive system, they are more often studied separately. A comprehensive within-group comparison on profiles lacking.We conducted whole-exome sequencing study cervical/endometrial/ovarian cancer samples from 209 Chinese patients. We combined our data with...
Dengue fever (DF) and dengue hemorrhagic (DHF) are recurrent diseases that widespread in the tropics. Here, we identified candidate genes associated with these by performing integrated analyses of DF (GSE51808) DHF (GSE18090) microarray datasets Gene Expression Omnibus (GEO). In all, 7635 differentially expressed (DEGs) 8147 DEGs as compared to healthy controls (P < 0.05). addition, discovered 215 long non-coding RNAs (DElncRNAs) 225 DElncRNAs DHF. There were 1256 common eight vs DF, normal...
This study aimed to investigate the value of preoperative indocyanine green (ICG) lymphography combined with ultrasonography for low-pressure vein localization in secondary lymphedema surgery breast cancer. A total 29 patients who were admitted department our hospital from July 2019 May 2021 included this study. All received reverse and surgery. Three arm circumferences measured before surgery, 6 months after 12 comparison healthy limb at same time. Arm circumference was significantly...
For patients with hepatocellular carcinoma and cirrhosis, the rupture of thin lymphatic vessel walls leads to a profuse outflow lymph fluid. Typically, chyloperitoneum tends precede development chylothorax in cancer. The present study describes case male patient who developed without chyloperitoneum. Computed tomography showed system developmental abnormalities large volume leaked Multiple thoracic duct ligations (TDLs) failed, but side‑to‑end venous anastomosis (LVA) surgery resolved...
Objective To explore the feasibility of breast reconstruction using thigh free dermal fat flap. Methods In January 4, 2017, a 27-year-old unmarried female patient with cancer was admitted to Department Breast Surgery, Affiliated Tumor Hospital Guangxi Medical University. She previously underwent tumor biopsy in another hospital. In our hospital, she pathologically diagnosed as having invasive micropapillary carcinoma right ER (+ , >90%), PR HER-2 (-), Ki67 about 30%). Preoperative...
Abstract Background and Objective : The morbidity mortality of breast cancer are increasing in recent years, which had become the second main cause death women. However, there different characteristics developing countries developed countries. What’s more, it has not reported comparison between southern China United States. We intend to compare age, stages grades tumor treatment methods, order study factors influence survival prognosis patients. Methods: To two groups have been diagnosed...
Abstract Background and Objective : There are different characteristics of BC in developing countries developed countries. We intend to study the factors which influence survival prognosis between southern China United States. Methods: To two groups patients from 2001 2016 SEER database 1975 2016. register, collect analyze clinicopathological features treatment information. Results: Our found that there significant differences tumor size, positive lymph node status KI-67 cohort ( P...