A5016794963- Genetic and phenotypic traits in livestock
- Prion Diseases and Protein Misfolding
- Trace Elements in Health
- Genetic Mapping and Diversity in Plants and Animals
- Mycobacterium research and diagnosis
- Neurological diseases and metabolism
- Herpesvirus Infections and Treatments
- Cancer-related molecular mechanisms research
- Reproductive Biology and Fertility
- Microbial infections and disease research
- Animal Nutrition and Physiology
- Metallurgy and Material Science
- Research in Cotton Cultivation
- Animal Disease Management and Epidemiology
- Meat and Animal Product Quality
- Reproductive Physiology in Livestock
- Toxoplasma gondii Research Studies
- melanin and skin pigmentation
- Helminth infection and control
- Ginseng Biological Effects and Applications
- Ruminant Nutrition and Digestive Physiology
- Animal Genetics and Reproduction
- HIV Research and Treatment
- Vector-Borne Animal Diseases
- vaccines and immunoinformatics approaches
Siirt Üniversitesi
2022-2025
Bandırma Onyedi Eylül University
2014-2022
This study investigates the genetic underpinnings of wool traits, specifically fibre diameter (FD) and staple length (SL), in Middle Anatolian Merino sheep using multi-locus genome-wide association (GWAS) approaches. Representing first attempt to examine these polygenic traits with methods, analysis employed four techniques: mrMLM, FASTmrMLM, FASTmrEMMA, ISIS EM-BLASSO. A total 18 Quantitative Trait Nucleotides (QTNs) were identified for FD, 7 co-detected by multiple 14 QTNs SL, 5 methods....
Toxoplasma gondii stands as one of the most successful pathogens, capable infecting nearly all warm-blooded species. It is estimated that up to 50% human population might harbor Toxoplasmosis infections. One primary transmission routes consumption tissue cysts from infected farm animals used for food production. Thus, controlling in vital importance health and safety. Selective breeding animals, where available, could complement classical control measures like biosecurity measures,...
This study details field investigations conducted during the 6th Turkish National Antarctic Science Expedition in February 2022, involving zooplankton sampling at ten stations along western shores of Horseshoe Island, Marguerite Bay. Utilizing a WP-2 plankton net, both vertical and horizontal methods were employed, with samples preserved for morphological molecular analysis. Morphological assessments collected focused on detailed descriptions supported by digital imaging. Following marine...
The genetic structure of 4 Turkish breeds sheep, Gökçeada, Kıvırcık, Karacabey Merino, and Sakız (SZ), was analyzed by genotyping with 17 microsatellite markers in 250 individuals. microsatellites showed high levels polymorphism, means for total effective number alleles per locus 20.71 7.04, respectively. average observed expected heterozygosity values were 0.66 0.87, It found that a higher level breed admixture existed the breeds, which an important finding. also 7.9% variation resulted...
The calpastatin (CAST) gene has a major effect on muscle growth and meat tenderness after slaughter; it is located the fifth chromosome in sheep. Blood samples were collected from 720 animals total Kıvırcık (KIV), Sakız (SZ), Karacabey Merino (KM), Gökçeada (GA) sheep populations raised West Anatolia. PCR products digested by restriction endonuclease MspI. Allele frequencies for M N alleles of found to be 0.85 0.15 KIV, 0.80 0.20 KM, 0.99 0.01 GA, 0.34 0.66 SZ sheep, respectively. It was...
Abstract Scrapie is a lethal neurodegenerative disease of sheep and goats caused by the misfolding prion protein. Variants such as M142, D145, S146, H154, Q211, K222 were experimentally found to increase resistance or extend scrapie incubation period in goats. We aimed identify polymorphisms Afar Arsi-Bale goat breeds Ethiopia computationally assess effect variants on protein stability. In present study, four non-synonymous novel G67S, W68R, G69D, R159H first octapeptide repeat highly...
Scrapie, the oldest prion disease of sheep, has two types: classical and atypical scrapie. It was determined that some nucleotide polymorphisms in PrP coding gene have affected scrapie susceptibility. Consequently, EU member states established breeding programs aiming to increase genetic resistance their flocks These primarily been implemented economically important breeds. Thus, we investigated related genotypes Karacabey merino breed, which is great economic importance western regions...
Bu çalışmada, Türkiye'nin bazı yerli koyun ırklarında (Kıvircik, Karacabey Merinos, Sakız Adası, Gökçeada, Cine Capari, Awassi ve Karakacan) BMP15 GDF9 gen bölgeleri DNA dizilimi yoluyla incelenmiştir. Ekson 2 bölgesinde iki Tek Nükleotid Polimorfizmi (SNP) tanımlandı: bir eşanlamlı SNP, P248P (Prolin/Prolin) olmayan L251P (Lösin/Prolin), bu da yanlış anlamlı mutasyonla sonuçlandı. 1 yalnızca SNP olan R87H (Histidin/Arginin) bulundu. Exon dört E241K (Glutamat/Lizin) V332I (Valin/İzolösin)...
Abstract Background Classical scrapie susceptibility in sheep has been linked to three polymorphisms at codon 136, 154, and 171 the prion protein gene ( PRNP) whereas atypical is related 141. Many other variants over length of PRNP have reported. Some may play crucial roles fighting against emergence a new form disease. Scrapie surveillance, associated genotyping characterization studies conducted across globe. However, such in-depth never addressed African continent’s breeds. Therefore,...
Abstract Visna/maedi (VM) is a multisystemic lentivirus infection of sheep that affecting industry across the globe. TMEM154 gene has been identified to be major VM-associated host gene, nevertheless, recent study showed frequency VM-resistant haplotypes was very low or absent in indigenous sheep. Thus, present designed determine other possible co-receptors associated with VM. For this purpose, DRB1 which renowned for its role immune response against various diseases targeted. A total number...
This study was conducted to determine first age reproduction characteristics of indigenous Kıvırcık, Sakız and Gökçeada sheep breeds growth performances ewe lambs which have been kept in Bandırma Sheep Research Station (BSRS). The data ewes were collected on 15 8 10 ewes, 16 12 11 lambs, respectively. After the completed their fifth month ages, estrus detection carried out with a teaser ram twice day hour intervals. For oestrus weights 37.93, 33.35 29.75 kg; ages 315, 320 337 days; durations...
Ovine Johne's disease (OJD) is caused by Mycobacterium avium subsp. paratuberculosis (MAP) and carries a potential zoonotic risk for humans. Selective breeding strategies reduced OJD susceptibility would be welcome tools in eradication efforts, if available. The Toll-like receptor 2 gene (TLR2) plays an important signaling role immune response to MAP, missense variants are associated with mycobacterial infections mammals. Our aim was identify evaluate ovine TLR2 association Turkish sheep....
Johne's disease is a chronic, contagious, zoonotic that affects numerous species including livestock and sometimes humans. The globally distributed in sheep populations caused by Mycobacterium avium Subsp. paratuberculosis (MAP). A previous genome-wide association study identified single nucleotide polymorphism (SNP) markers associated with OJD serostatus CD109, PCP4, SEMA3D genes. Our aim was to evaluate the same for seroprevalence Turkish retrospective matched case-control study....
<title>Abstract</title> There are fewer studies investigating the effects of underlying genetic factors related to semen characteristics, which significantly affect sheep farm profitability. This study represents first Genome-Wide Association Study (GWAS) comparing backgrounds two composite breeds with high (Hasmer) and low (Hasak) cryotolerance. To unravel background cryotolerance parameters, was collected from rams via an artificial vagina cryopreserved in 0.25 ml straws during breeding...