A5085158419- BRCA gene mutations in cancer
- Ethics in Clinical Research
- Prenatal Screening and Diagnostics
- Genomics and Rare Diseases
- Nutrition, Genetics, and Disease
- Genetics, Aging, and Longevity in Model Organisms
Virginia Commonwealth University
2023
University of California, Santa Cruz
2017-2018
The BRCA Challenge is a long-term data-sharing project initiated within the Global Alliance for Genomics and Health (GA4GH) to aggregate BRCA1 BRCA2 data support highly collaborative research activities. Its goal generate an informed current understanding of impact genetic variation on cancer risk across iconic predisposition genes, BRCA2. Initially, reported variants in available from public databases were integrated into single, newly created site, www.brcaexchange.org. purpose Exchange...
Abstract As cost-effective next-generation genome sequencing rapidly develops, calls for greater inclusion of Black people in genomic research, policy, and practice are necessary effective translation science into precision population health medicine. Employing a community-based participatory mixed methods research design, we developed semi-structured survey that was disseminated to three cancer advocacy organizations. Of the 81 respondents 49 (60%) self-identified as Black, 26 (32%)...
Public health genomics prioritizes effective and ethical translation of genomic science into population precision medicine. With the rapid development cost-effective, next-generation genome sequencing, calls are growing for greater inclusion Black people in research, policy, practice. Genetic testing is often first step This study explores racial differences patient concerns about genetic hereditary breast cancer. Employing a community-based participatory mixed methods research design, we...