A5047801628- Muscle metabolism and nutrition
- Diet and metabolism studies
- Nutritional Studies and Diet
- Nutrition and Health in Aging
- Obesity, Physical Activity, Diet
- Nutrition, Genetics, and Disease
- Nutrition, Health and Food Behavior
- Folate and B Vitamins Research
- Body Composition Measurement Techniques
- Health Systems, Economic Evaluations, Quality of Life
- Pharmacological Effects and Assays
- High Altitude and Hypoxia
- Meta-analysis and systematic reviews
- Clinical practice guidelines implementation
- Metabolism and Genetic Disorders
- Clinical Nutrition and Gastroenterology
- Ethics in Clinical Research
- Biochemical effects in animals
Hospital for Sick Children
2019-2024
University of Toronto
2019-2022
The conduct of high-quality pilot studies can help inform the success larger clinical trials. Guidelines have been recently developed for reporting trials.This methodological survey evaluates completeness in randomized controlled trials chronic kidney disease patients on hemodialysis (HD patients) and explores factors associated with better completion reporting.The authors searched Pubmed July 1, 2018, all conducted HD patients. Reporting quality was assessed against 40-item Consolidated...
The goals of the current study were to 1) define lysine requirement in female adults >60years using indicator amino acid oxidation method (IAAO) with L-[1–13C]phenylalanine as and 2) compare derived estimate our previous estimates young women done both luteal follicular phase mensural cycle. Sixteen healthy (>60 years) randomly assigned receive 3 7 intakes from 10 80 mg. kg−1. d−1. Subjects adapted a standard liquid diet providing 1.0 g. kg−1.d−1protein adequate energy, for 2 days,...
The objective of the current study was to determine leucine requirement in older adult men using indicator amino acid oxidation (IAAO) method. for determined IAAO with L-[1-13C]phenylalanine as indicator. Using a repeated measures design, seven healthy were randomly assigned receive out nine intakes leucine: 20, 30, 45, 55, 70, 80, 90, 105, 120 mg· kg–1· d–1. rate release 13CO2from measured and breakpoint analysis non-linear mixed effects model (PROC NLMIXED) applied requirement. upper 95%...
The objective of the current study was to determine whether 3 or 7 days, compared 8 hours adaptation test level threonine intake alters requirement in healthy young men. 11 men (19–35 years) were studied at 6 levels (5, 10, 15, 20, 25 and 35 mg.kg−1.d−1), random order. Participants first habituated a diet containing intact milk protein (1.0 g.kg−1.d−1) adequate calories for 2 days. Subjects then received an experimental intakes with IAAO studies performed on days 1, 3, 7. A total 162...