A5081710261- Legionella and Acanthamoeba research
- Yersinia bacterium, plague, ectoparasites research
- Essential Oils and Antimicrobial Activity
- Research on Leishmaniasis Studies
- Synthesis and bioactivity of alkaloids
- History of Medicine Studies
- Phytochemistry and Biological Activities
- Bacterial biofilms and quorum sensing
- Medicinal plant effects and applications
- Wound Healing and Treatments
- Ocular Infections and Treatments
- Synthesis and Biological Evaluation
- Burn Injury Management and Outcomes
- Bioactive Compounds and Antitumor Agents
- Dietary Effects on Health
- SARS-CoV-2 and COVID-19 Research
- Gastrointestinal motility and disorders
- Bioactive Natural Diterpenoids Research
- Herpesvirus Infections and Treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Urticaria and Related Conditions
- Families in Therapy and Culture
- Drug-Induced Hepatotoxicity and Protection
- Toxoplasma gondii Research Studies
- Olfactory and Sensory Function Studies
Semnan University of Medical Sciences
2022
Shahed University
2011-2020
Leishmaniasis is an important disease in humans. Leishmania homologue of receptor for Activated C Kinase ( LACK ) and thiol specific antioxidant TSA as immuno‐dominant antigens major are considered the most promising molecules a DNA vaccine. We constructed cocktail, containing plasmids encoding genes evaluated immune response survival rate BALB /c mice. IgG Interferon gamma values were noticeably increased immunized group with cocktail vaccine, which significantly higher than those...
Introduction: Arnebia euchroma ointment has been used in Iranian Traditional Medicine for burn wound healing. The aim of this study is to evaluate healing efficacy A. on wounds induced after fractional CO2 laser rats.Material and methods: In study, anesthetizing two bilateral were dorsal skin the rat using ablative laser. After applying laser, ointment, petrolatum, silver sulfadiazine cream topically twice daily 10 days. Digital photographs captured from surfaces every day. At end blinded...
Mentha spicata is a herb with several biological properties. Cytotoxicity of essential oils M. on some cancer cells has been reported. In this study the cytotoxicity aqueous extract two tumor cell lines (Wehi-164 fibrosarcoma and U937 leukemic monocyte) evaluated in vitro . Wehi-164 were separately cultured RPMI 10% FBS. Then at logarithmic growth phase incubated presence different concentrations (0.1 to 10 mg/ml) 24, 48 72 h periods. The proliferation was assessed trypan blue dye exclusion...
: Burns are a worldwide problem. The incidence of severe burns has been higher than the combined tuberculosis and HIV infections. Throughout history there have many different treatments prescribed for burns. Canon is masterpiece Avicenna's medical books. includes description 785 simple drugs. Avicenna believed in burn treatment, which follows two goals. first goal prevention blistering second treatment wound after it created blisters, cold drugs suitable dry with moderate hot qualities...
Arnebia euchroma ointment (AEO) has been used in Iranian traditional medicine for burn wound healing.The aim of this study is to evaluate healing efficacy AEO wounds after fractional Co2 laser.This split-face, single-blinded, single-center clinical was performed Shohada-e-Tajrish Hospital, Tehran, Iran. A total 26 subjects with facial acne scar, who were receive CO2 laser resurfacing recruited. After procedure, applied one side the face and petrolatum on other healing. Digital photographs...
Leishmaniasis is one of the six most common parasitic infections in tropical regions. There are different therapeutic modalities, however resistance developed and resulted numerous problems. Therefore, evaluation other modalities performed extensively.The current study aimed to compare response cutaneous leishmaniasis with Glucantime Peganum harmala extracts (aqueous ethanol) animal model.The Leishmania major P. model was studied BALB/c mice. These mice were divided into four groups...
Background and Aims: Amoebae of the genus Acanthamoeba are unicellular amphizoic opportunistic pathogens that may cause fatal granulomatous encephalitis, eye keratitis, amebic pneumonitis skin nodules as well abscesses in humans animals. keratitis is caused by trauma to eye, contaminated cleaning solutions use contact lenses. The aim present study was identify genotypes all patients with a clinical diagnosis referring clinic Tehran using polymerase chain reaction (PCR). Materials Methods: In...
Background: Acanthamoebiasis treatment is a major and challenging problem due to the presence of resistant cyst form. Many herbal extracts their derivatives have been used against trophozoites cysts Acanthamoeba, but no effective therapeutic agent has yet discovered. Therefore, present study aimed evaluate effect Rumex obtusifolius (R. obtusifolius) clinical strain Acanthamoeba genotype T4 in vitro. Methods: In this experimental study, after genotyping isolate, hydroalcohlic R. seeds leaves...
Dry eye disease is a relatively common disorder associated with decrease in quality of life. In this study, efficacy an drop Plantago ovata mucilage on symptoms dry was evaluated. randomized, double-blind, placebo-controlled clinical trial, sixty patients ocular and total Ocular Surface Disease Index (OSDI) score ≥12 were randomly assigned to receive either natural ophthalmic drop, made or placebo 4 times day for 6 weeks. The evaluated at pretreatment (baseline), weeks post-treatment....
Background and Aims: Acanthamoeba is a ubiquitous amphizoic organism which can cause lethal diseases such as granulomatous amoebic encephalitis unfortunately, the infection has now increased in world. The aim here was to evaluate vitro anti-Acanthamoeba properties of crude aqueous ethanolic extracts Myrtus communis.Materials Methods: In this experimental research, clinical isolate cultured genotyped. communis were prepared. Then, various concentrations (1.25, 2.5, 5, 10 mg/ml) tested at...