Systemic lupus erythematosus (SLE) is an autoimmune disease with unknown etiology. It involves multiple organs and presents as varying clinical manifestations such renal involvement (nephritis) hematological disorders.One hundred sixty people, divided equally into two groups: SLE patients, diagnosed according to the 2010 American College of Rheumatology/European League Against Rheumatism criteria, healthy controls matched in age gender, attending University Hospitals between April 2019...

People with ankylosing spondylitis (AS) are vulnerable group to experience mood disorders. It is crucial identify factors that contribute depression and anxiety in order improve outcomes. This study seeks determine the rates of Syrian AS patients, as well potential predictors for these conditions. cross-sectional was conducted using convenience sampling at Biological Treatment Unit Rheumatology Department Damascus Hospital. Data were collected from face-to-face interviews patients validated...

IgG4-related disease (IgG4-RD) is a rare but increasingly recognised condition that can involve multiple organs, including the kidneys which often presents as tubulointerstitial nephritis. Treatment with glucocorticoids first line of therapy, other options may be needed in refractory cases. This case report explores 68-year-old female, diagnosed patient initially responded to had relapse, leading progressive renal insufficiency and ultimately death. Our observing progression end-stage kidney...

<b>Background:</b> Emotional intelligence (EI) refers to the capacity understand, express, perceive, and manage emotions. It encompasses self-regulation, self-awareness, social skills, motivation, empathy as its five fundamental components. Evidence shows that there is a relationship between EI many components of clinical practice, such during medical consultations, building strong physician patient, improving performance, increasing patient satisfaction.<br />...

Advances in Medical, Dental and Health Sciences,2020,3,3,45-48.DOI:10.5530/amdhs.2020.3.11Published:October 2020Type:Research ArticleAuthors:Louay Labban, Maysoun Kudsi, Zeina Malek, Nasser Thallaj Author(s) affiliations:Louay Labban1,*, Kudsi2,4, Malek3, Thallaj4 1Faculty of Pharmacy, Al Jazeera Private University, Damascus, SYRIA. 2Faculty Medicine, Damascus 3Faculty Syrian 4Faculty Rasheed SYRIA.Abstract:Objectives: To evaluate the efficacy safety Echinacea ginger species extracts...

Osteoporosis is a progressive decline in the bone mass, which occurs with no alterations to bone's composition. It associated increased fragility that may eventually lead fractures. In this study, we aim assess level of awareness Syrian women possess regarding osteoporosis and spread knowledge about its prevention measures.This study was approved by Institutional Review Board Private University. A validated questionnaire asked be filled aged 18 above, who were presented clinics at Damascus,...

The incidence of neurological injury in primary Sjogren's syndrome varies between 2.5 and 60%. authors aimed to evaluate its prevalence characteristics patients with a sample the Syrian population.Forty-eight syndrome, attending outpatient clinics at Damascus Hospital January 2020 2022 this cross-sectional study clinics, were interviewed examined, necessary laboratory radiological examinations demanded. Information was collected on disease duration, onset time, patterns symptoms.Forty-eight...

Sjögren's syndrome is an autoimmune disease affecting exocrine glands and other organs. At the onset of during its course, it most commonly manifests as neuropsychiatric symptoms, frequently, depression anxiety. However, association with bipolar disorder seems rare not frequently documented.Our case report presents a 43-year-old male complaining from symptoms including but limited to periods elevated mood, increased energy, headaches. Examination revealed xerophthalmia xerostomia, thus...

Introduction: Although central nervous system demyelinating lesions as a side effect of tumor necrosis factor (TNF)-alpha inhibitors have been reported, this treatment is still used in some autoimmune diseases. Case Presentation: A 34-year-old Syrian male presented with difficulty walking and tingling, numbness on the left his body over next 4 days, during golimumab treatment. Over past 2 months, fatigue, recurrent calf spasms, extremity were found. Sense disturbance hyper-reflexes lower...

Abstract Introduction Low back pain related to pregnancy occurs in 60%–70% of pregnancies, at any time during pregnancy. During pregnancy, many factors such as weight gain, and others are the causes pain. In Syria, due circumstances war, pregnant women may be exposed increase risk lower pain, so this study will determine prevalence among its potential factors. We aimed evaluate low assess it. Methods A cross‐sectional, observational was conducted between May 2020 December 2022 Obstetrics...

Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can involve any organ system, and may lead to significant morbidity even mortality. Down syndrome (DS) the most frequent genetic cause of intellectual disabilities, typically caused by presence an extra chromosome 21. Case presentation: A 47-year-old Syrian female DS who complained low-grade fever, oral aphthae, fatigue, arthralgia three months before presentation. Although patient was diagnosed with...

Systemic lupus erythematosus (SLE) is a systemic immune disease that classically occurs in young to middle-aged women and may present with cutaneous, renal, haematologic, neurological, and/or other symptoms at the time of diagnosis. Late-onset SLE or elderly subtype differs from classic terms age group, clinical symptoms, organ involvement severity.

Abstract Background Nintedanib was approved for the treatment of scleroderma and scleroderma-related interstitial lung disease, as it decrease forced expiratory volume. Case presentation A 48-year-old Asian female patient with systemic 6 years ago developed breathlessness, nausea, heart palpation, sudden severe occipital headache over preceding week. She receiving aspirin 81 mg/day amlodipine 5 mg/day. Her diagnosis diffuse pulmonary hypertension, involvement, renal crisis. The modified...

Introduction and importance: The COVID-19 pandemic has led to a post-acute syndrome that can persist for an extended period. correlation between anorexia nervosa (AN) some autoimmune diseases been reported. Systemic lupus erythematosus (SLE) is systemic disease, presented with different clinical ions periods, affecting all ages, especially females. coexistence of SLE AN reported in rare cases. authors present the case 22-year-old male severe coexisting SLE. Case presentation: We diagnosed He...

Uveitis, as an extra-articular presentation, is found in 23% of patients with ankylosing spondylitis (AS) and a challenging disease to treat.

Introduction: IgA vasculitis is generally triggered by infections and vaccines. Herein, we report a case of young man who was previously healthy developed after the first dose COVID-19 mRNA vaccine Pfizer-BioNTech. Case presentation: The patient’s symptoms were mainly skin joint without renal or other system involvement. patient had an excellent outcome with complete resolution treatment steroid tapering azathioprine as steroid-sparing agent over 6 months.

Systemic sclerosis is a connective tissue condition presented with clinical manifestations, including ocular involvement in small percentage. A few cases of uveitis were described the literature, especially CREST syndrome.The authors reported case 48-year-old male blurred vision his left eye that diagnosed recurrent setting syndrome, treated prednisolone, methotrexate, and golimumab, improvement.Ocular manifestations systemic include palpebral alterations, keratoconjunctivitis, sicca...

Calciphylaxis manifests clinically by skin ischemia and necrosis histologically calcification of dermal arterioles. Usually, it occurs in patients with end-stage renal disease on dialysis or who had a kidney transplant. Here, the authors present case calciphylaxis occurring patient psoriasis psoriatic arthritis.A 66-year-old Syrian male history arthritis presented for evaluation 2-month nonpainful ulcers his feet hands that were treated warfarin. Biopsies confirmed diagnosis calciphylaxis....

The diagnosis of sarcoidosis and Sjögren's syndrome (SS) in the same patient is a challenge since considered an exclusion criterion for SS.The authors described 62-year-old woman, who had SS 8 years presented with dry mouth, eyes, dyspnoea, erythema nodosum. High resolution computed tomography chest showed symmetrical pulmonary micronodules, interstitial changes, enlarged mediastinal lymph nodes. Anti-nuclear antibodies anti-SSA were positive. Schermer's test was also A biopsy lung nodules...

Background: Behçet's disease is a multisystem autoimmune disorder of unknown origin, characterized by frequent oral and genital ulcerations, ocular cutaneous lesions, arthritis, it may also involve the gastrointestinal, central nervous system. In this paper we discuss case Behcet syndrome presenting with isolated aphthous initially spotlight on clinical features treatment. Case report: A 32-year-old male repetitive tongue inner cheeks for four days history recurrence. The patient responded...

Abstract Introduction Rheumatic diseases are autoimmune inflammatory that affect mainly joints, muscles, and systemic organs, leading to a public health challenge for the world. Providing society with good-quality information is important management of chronic diseases. We aim in our study assess awareness rheumatic sample Syrian population Material Methods This web-based cross-sectional survey was conducted Damascus, Syria, between 1 Dec.2021 Dec. 2022. All participants above age 18 were...

Erythema nodosum (EN) is a self-limited septal panniculitis that presents with fever, arthralgia, and arthritis. Tumor necrosis factor alpha (TNF-α) inhibitor such as golimumab has been found to treat EN in inflammatory bowel diseases (IBD). We herein report the paradoxical occurrence of following for ankylosing spondylitis.A 34-year-old female presented June 2022 complaint 'sores' on her feet intermittently approximately 5 months but had worsened dramatically last 24 h. The patient an...

Introduction: In the United States, tocilizumab was approved for treatment of scleroderma and scleroderma-related interstitial lung disease because it inhibited decrease in forced expiratory volume, so is entering a new era. Case presentation: A 44-year-old female patient with systemic scleroderma, diagnosed 6 years ago, presented breathlessness over last week. The modified Rodnan’s score 18. Tocilizumab 162 mg subcutaneously once every 2 weeks prescribed. After 4 weeks, Rodnan observed....

Key Clinical Message Our case reported a 22‐year‐old male presented with headache, and sudden vision loss, 10 days after receiving the first dose of COVID‐19 vaccination. Counting fingers in both eyes was his visual acuity on examination bilateral optic disc edema fundoscopy found. Brain MRI normal. After methylprednisolone pulse therapy, plasmapheresis, IV cyclophosphamide courses, disappeared, function did not improve. Reported cases neuritis develop mRNA vaccination are limited.