- Cancer Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Sarcoma Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Gastric Cancer Management and Outcomes
- Urinary and Genital Oncology Studies
- Renal cell carcinoma treatment
- Head and Neck Cancer Studies
- Cancer and Skin Lesions
- Urologic and reproductive health conditions
- Lung Cancer Treatments and Mutations
- Urological Disorders and Treatments
- Breast Lesions and Carcinomas
- Global Cancer Incidence and Screening
- Neuroendocrine Tumor Research Advances
- Orthopedic Infections and Treatments
- CNS Lymphoma Diagnosis and Treatment
- Brain Metastases and Treatment
- Economic and Financial Impacts of Cancer
- Thyroid Cancer Diagnosis and Treatment
- Inflammatory Biomarkers in Disease Prognosis
- Radiopharmaceutical Chemistry and Applications
- Prostate Cancer Treatment and Research
- Cervical Cancer and HPV Research
Dr. Rajendra Prasad Government Medical College
2024-2025
Post Graduate Institute of Medical Education and Research
2021-2024
Government Medical College
2024
Government Medical College and Hospital
2019-2023
Indira Gandhi Medical College
2020
Gandhi Medical College & Hospital
2020
F-FDG PET/CT has been used to characterize the primary lesion and staging in head neck cancers (HNC). However, prior studies for detecting distant metastasis synchronous tumors are sparse, especially Indian context. To investigate frequency distribution of carcinomas, metastases malignancies detected HNC a north population.
Abstract Background Polish and Australian randomized studies compared short-course radiotherapy (RT) with immediate surgery long-course chemoradiotherapy (CRT) delayed surgery. In these studies, similar long-term survival local control have been reported for both approaches, but pathological complete response (pCR) is not better RT. Moreover, shown tumor downstaging this context, the use of RT may some advantages needs to be tested in clinical trials. Patients Methods This was a two-arm,...
Primary central nervous system-diffuse large B-cell lymphoma (PCNS-DLBCL) is a rare, extranodal malignant carrying poor prognosis. The prognostic impact of tumor microenvironment (TME) composition and the PD-1/PD-L1 immune checkpoint pathway are still undetermined in PCNS-DLBCL. We aimed to quantify tumor-infiltrating lymphocytes (TILs), tumor-associated macrophages (TAMs), PD-L1 expression PCNSL evaluated their significance. All patients with histopathologically diagnosed PCNS-DLBCL over...
We undertook a prospective planning study to describe the delineation of ileal conduit (IC) loop on radiotherapy computed tomography (RTP CT) scan as an organ at risk (OAR) and its sparing using volumetric modulated arc therapy (VMAT) during adjuvant irradiation bladder malignancies.Fifteen patients with malignancy needing postoperatively having normal renal function underwent delayed phase RTP CT from June 2020 March 2021, certain modifications (Foley's catheter through stoma, additional...
Abstract Patients with autosomal dominant polycystic kidney disease (ADPKD), especially those renal failure, carry a higher risk of developing cell carcinoma (RCC) compared to the general population. Genetic mutations associated ADPKD are known but direct link RCC is still controversial. We discuss clinical course two such patients. The first patient was diagnosed at age 10 years an unreported tubulocystic focus on his biopsy that picked up review 16 later when he presented vertebral...
Background: Cancer forms the second-most common cause of death worldwide. Once a patient is diagnosed with cancer, socioeconomic life altogether changed. In developing countries, like India, as prevalence cancer increasing, policies and schemes need to be incorporated overcome financial burden disease. This study was aimed know in our country, so further improve health economics. Materials Methods: prospective done over period 2 years. Three thousand twelve patients were enrolled this that...
Carcinoma of esophagus is one the cancers with a high mortality rate. Metastasis esophageal carcinoma in lymph nodes, lung, liver, bones, and adrenal glands common pattern. Nowadays, uncommon sites metastasis are increasingly reported including skin. Cutaneous squamous cell more than adenocarcinoma. Here, we present three cases cutaneous patients esophagus, out which two were seen was The prognosis such dismal they treated palliative chemotherapy.
Background: Metastatic urothelial carcinoma bladder at the time of diagnosis is a rare entity with lymph nodes, bones, lung and liver as common metastatic sites. Sometimes metastasis can be seen in various atypical sites.Case Presentation: Unusual location perinephric region, renal fascia ovaries described case. Primary ovary needs to differentiated from metastasis. There are no standard lines management treatment individualised. Prognosis remains fatal limited life expectancy. Conclusion:...
Abstract Squamous cell carcinoma (SCC) of the conjunctiva is rare. It commonly associated with ultraviolet ray exposure, viral infections, and conjunctivitis. Its management includes surgical excision adjuvant treatment. Surgery alone leads to a high risk recurrence even in early stages. Local most common, chemotherapy preferred over resurgery such cases. Lymphatic distant metastases are seen advanced Here, we present an elderly female early-stage SCC who underwent surgery alone, defaulted,...
Abstract Purpose To compare the standard International Commission on Radiation Units and Measurements-38 (ICRU-38) rectum bladder point doses with a modified technique of combining radio-opaque vaginal packing (VP) rectal retractor (RR) versus conventional using RR alone for separation during high-dose-rate (HDR)-intracavitary brachytherapy (ICB) tandem-ring (TR) applicators. Methods Between January 2021 August 2022, 41 cancer patients received at least one ICB session same applicator set...
Neuroendocrine carcinoma breast is a distinct entity. Although clinical features and morphology cannot distinguish it from invasive carcinomas, immunochemistry plays an important role in it. Due to its rarity lack of data, treatment followed on the lines carcinoma. Some studies have suggested use cisplatin etoposide for treatment, but none them standard. The prognosis poor compared cancer.
Introduction: Carcinoma cervix still forms a major burden in India; also, anemia is seen commonly Indian females. Hemoglobin (Hb) level one of the prognostic factors carcinoma cervix. The association Hb levels with response not well established. However, >11 g% have shown good number studies. Materials and Methods: This study enrolled patients cervix, <70 years old Stage IIA to IVA, histologically squamous cell carcinoma, adenocarcinoma, adenosquamous carcinoma. Accelerated concurrent...
Introduction: Cervical cancer ranks fourth in women worldwide. The management requires a multidisciplinary approach. Concomitant chemoradiotherapy with cisplatin, followed by brachytherapy, is the standard Accelerated radiotherapy (ART) can be used to decrease treatment duration which further lead better outcomes. Materials and Methods: Stages II, III, IVA of carcinoma cervix were studied for 1 year. Ninety patients randomized control study arms, 45 each arm. total dose radiation was 50...
Groin node metastases are predominantly seen in primary malignancies of infradiaphragmatic location. However, sparse cases inguinal from tumors above the diaphragm have been reported medical literature. Here, we report a case small-cell carcinoma lung with metastatic lymph at initial presentation 57-year-old man. The was diagnosed and managed congruously as per stage disease, which metastatic. patient died due to disease progression after 8 months diagnosis. This edifies clinical...
Metaplastic carcinoma of breast is a rare form tumour in which there mixture malignant mesenchymal and epithelial elements. In these tumours cancerous cells origin are found combination with non-specific spindle origin. It an aggressive cancer usually appears late stages.
Introduction: Renal cell carcinoma metastasizes commonly to visceral organs such as adrenals, liver, lungs, or bones. Metastases body cavities pleura, pericardium and peritoneum are rare, almost never in isolation. Case discussion: We discuss here a patient who was diagnosed with renal following an episode of hematuria underwent radical nephrectomy for the same. Within month surgery, he evaluated sudden onset breathlessness detected have massive left-sided pleural effusion, which returned...
Abstract Background Leiomyosarcomas of urinary bladder constitute rare malignant sarcomas with very few cases reported in literature. Case presentation Here, we present a case leiomyosarcoma well-preserved female. She failed to respond standard chemotherapy and had rapidly downhill course unusual metastases anastomotic site peritoneum soon after surgery. Despite multimodality management including resection primary metastatic site, systemic therapy pelvic radiotherapy, our patient dismal...
Background: Head and neck cancers constitute 6% of worldwide. The management requires a multidisciplinary approach. Concomitant chemoradiotherapy with cisplatin is the standard approach for locally advanced head cancers. most commonly used regime uses three weekly which more toxic. Low-dose once-a-week substituted because perceived lower toxicity convenience. Methods: Squamous cell carcinoma stage III, IVA IVB oropharynx, hypopharynx larynx were studied one year. 82 patients studied. Total...
Ewing's sarcoma is the 2nd most common paediatric bone tumour but can also be seen in extraskeletal sites. Superficial ES a rare entity and rarely foot. Majority of these patients are females second decade life, presenting with small, single mass, mobile, sometimes painful. They usually have favourable outcome due to infrequent metastasis.