Malignant small round blue cell tumors encompass a diverse group of aggressive neoplasms that share overlapping histological features, making diagnosis challenging based on morphology alone. We case mesenchymal chondrosarcoma to illustrate this challenge and discuss the differential diagnosis. Soft, cream-tan tissue fragments with tan, grainy surfaces were submitted from an incisional biopsy taken left maxillary alveolar bone 6 year-old female. Microscopically, tumor was composed primarily...

Olfactory neuroblastomas (esthesioneuroblastomas, ONB) are rare malignant neoplasms that arise from sensory neuroepithelial (neuroectodermal) olfactory cells found in the superior nasal concha and cribriform plate of ethmoid sinus. ONBs comprise approximately 5% sinonasal tract malignancies, affect both genders equally primarily involve middle aged adult group (range 3 – 79 years). The most common presenting symptoms unilateral obstruction, epistaxis a fairly slow-growing mass high cavity or...

A 23-year-old woman underwent left thyroid lobectomy and isthmusectomy for a 2 cm diameter firm mass on the side of neck that was also visualized ultrasonography. The specimen consisted 22-gram gland composed lobe, isthmus pyramidal lobe. Cut section lobe showed 3.5 solitary, discrete encapsulated with tan lobulated solid cut surface. rest tissues had red-brown meaty surfaces. Microscopic shows follicular-patterned proliferation enclosed by thin fibrous capsule frequent Sanderson...

The World Health Organization (2005) defines an epithelial-myoepithelial carcinoma (EMC) as a malignancy composed of two cell types that typically form duct-like structures.1 We present herein archival case from the parotid gland.
 
 EMC occurs primarily in major salivary glands particularly where it presents painless, slow-growing mass.1 Microscopic examination shows bi-layered tubular structures with pale to clear areas (Figure 1). inner luminal layer is cuboidal cells are...

A 27-year-old man presented with an 8 cm diameter left maxillary mass and enlarged cervical lymph node at levels II to III. There was a reported history of previous unspecified operation on the which had yielded diagnosis ameloblastoma. Total maxillectomy modified radical neck dissection subsequently performed.
 Microscopic examination shows epithelial islands cords in fibro-collagenous stroma. (Figure 1) The are lined periphery by palisaded columnar cells regular ovoid nuclei...

Tumour-induced osteomalacia is a paraneoplastic syndrome wherein bone affected by hormone from tumour that causes renal phosphate wasting and hypophosphataemia. Here, we present the case of 31-year-old man who has been suffering generalised pains spine deformity led to loss height. Pertinent findings are low serum phosphorus, vitamin D decreased mineral density. These diagnosis osteomalacia. However, finding an oral mass raised some questions as what role it plays in patient's disease. It...


 A 65-year-old man consulted with a history of chronic snorting sensation obstruction in the left side nasopharynx particularly when supine position. few days prior to consult, patient had blood-tinged nasal discharge, thus this admission. No other symptoms were reported.
 Nasal endoscopy showed sessile exophytic lesion vaguely nodular surface, seen as polypoid nasopharyngeal mass on Computed Tomography scan. (Figure 1)
 Excision was performed. Received surgical pathology...

Olfactory neuroblastomas (esthesioneuroblastomas, ONB) are rare malignant neoplasms that arise from sensory neuroepithelial (neuroectodermal) olfactory cells found in the superior nasal concha and cribriform plate of ethmoid sinus. ONBs comprise approximately 5% sinonasal tract malignancies, affect both genders equally primarily involve middle aged adult group (range 3 – 79 years). The most common presenting symptoms unilateral obstruction, epistaxis a fairly slow-growing mass high cavity or...

Primary sinonasal ameloblastoma is an extremely rare odontogenic epithelial tumor histomorphologically identical to its gnathic counterparts but with distinct epidemiologic and clinicopathologic characteristics. We present a case of 46 female 1 year history recurrent epistaxis, nasal obstruction, frontonasal headache. Clinical examination, CT scan, subsequent surgical excsion revealed intranasal mass attached the lateral cavity histomorphologic features was signed out as extragnathic soft...

Dedifferentiated Chordomas are rare variants of a malignant bone tumor arising from remnants the embryonal notochord.Most cases reported chordomas that have recurred after surgical resection and/or radiation.Dedifferentiated an overall poorer prognosis compared with conventional due to their highly aggressive behavior and high metastatic potential.We report case Chordoma sacrum in 53-year-old female no known prior surgery or radiation treatment.The associated clinical radiologic features...

A 41-year-old man presented with an 8-year history of recurrent mouth ulcers, previously treated unrecalled antibiotics and vitamins but no relief. Examination showed a 2.0 x 1.0 cm hard, immovable ulcer at the right lateral tongue. On further interview, repeated biting trauma on site lesion was elicited. The clinical impression non-healing tongue ulcer. Incision biopsy performed specimen sent for histopathologic evaluation. consisted three, cream-tan, irregularly-shaped soft tissues...

A case of melanotic neuroectodermal tumor infancy (MNETI) is presented. The salient
 histopathologic features this unusual neoplasm are discussed including post-chemotherapy
 morphologic changes.
 
 Keywords: Melanotic infancy, retinal anlage tumor, progonoma,
 tumors
 Neuroectodermal Tumor Infancy a rare early arising from neural crest cells, with rapid expansile growth and high recurrence rate.1 Most cases occur in the anterior maxillary alveolus. Prognosis...

Background. Newborn screening (NBS) is a procedure for the immediate detection of genetic, metabolic, and endocrine disorders in neonates crucial prompt treatment should such be identified. In Philippines, Republic Act 9288 requires health workers to properly inform mothers regarding NBS its importance before procedure. Objective. To determine knowledge, attitude, awareness primiparous postpartum towards Methods: A survey questionnaire was administered from Wards 15 16 Philippine General...

A 57-year-old woman with a 2-year history of left infra-auricular mass no associated symptoms presented 6.0 cm ´ 4.0 3.0 firm, non-tender, movable mass. No imaging was done. Fine needle aspiration biopsy (FNAB) revealed sheets epithelial cells that had abundant dense grayish-blue cytoplasm in mucinous background lymphocytes (Figure 1), suggestive salivary gland neoplasm oncocytic or oncocytoid features (Category IVB, Salivary Gland Neoplasm Uncertain Malignant Potential).1 Total...

A 54-year-old woman underwent total thyroidectomy for a one-year history of anterior neck mass. The specimen was 29.88–gram thyroid gland that on sectioning showed single 2.0 x 1.5 cm encapsulated nodule with tan-brown solid cut surfaces noted the right lobe. No gross lesions were isthmus and left Microscopic examination thinly composed tightly-packed follicles. (Figure 1) Examination entire capsule did not show capsular or vascular invasion. follicles lined by follicular cells had crowded...

A 37-year-old woman consulted for a slow-growing mass of one-year duration on the left side mandible with associated tooth mobility. Clinical examination showed buccal expansion along hemi-mandible from mid-body to molar-ramus region mobility and displacement pre-molar molar teeth. Radiographs well-defined unilocular radiolucency root resorption overlying Decompression unroofing cystic lesion was performed. Received in surgical pathology laboratory were several gray-white rubbery focally...

Objective: To present an unusual cause of pulsatile tinnitus, presenting in a young adult suffering from chronic recurrent foul-smelling discharge the same ear.
 Methods:
 Study Design: Case report
 Setting: Tertiary National University Hospital
 Patient: One
 
 Results: A 24-year old woman presented with tinnitus on background discharge. Clinico-radiologic findings seemed consistent glomus tympanicum coexisting suppurative otitis media cholesteatoma. She...

A 42-year old Filipino male with a 10-month history of progressive left nasal obstruction and rhinorrhea clinical impression polyposis underwent endoscopic sinus surgery partial ethmoidectomy polypectomy.
 We received several dark-brown, irregular, rubbery tissue fragments an aggregate diameter 3 cm. Histopathologic examination shows sheets spindly tumor cells beneath the respiratory epithelial lining. These spindle are closely packed arranged in short fascicles storiform clusters...

Malignant glandular neoplasms of the sinonasal tract originate either from respiratory epithelium or underlying mucoserous glands. They present with a confusing array morphologic features and this is reflected in nomenclature these tumors. These tumors are grouped into three main types: salivary gland-type, intestinal-type non-intestinal type adenocarcinomas.1 Salivary gland-type adenocarcinomas nasal cavity histologically resemble their analogous lesions major minor Adenoid cystic carcinoma...

A 63-year old Filipino female presented with epistaxis of undisclosed duration. Examination showed a vascular, pulsating, rubbery intranasal mass involving both nasal cavities. The clinical impression was that hemangioma. She underwent excision the tumor and specimen sent for histopathologic evaluation.
 
 consisted several tan-brown irregular tissue fragments an aggregate diameter 2 cm. Microscopic examination cellular spindle cell underneath respiratory mucosa. (Figure 1) cells...

Background. A fine needle aspiration biopsy has been established as a safe, minimally invasive procedure in evaluation of salivary gland lesions. The complex overlapping cytomorphology these lesions are challenging for pathologists, hence the introduction an evidence-based system, Milan System Reporting Salivary Gland Cytopathology, to improve overall patient care. study was taken up reclassify from previous FNA biopsies order determine sensitivity, specificity, positive and negative...