A5049173600- Botanical Studies and Applications
- Plant Pathogens and Fungal Diseases
- Dermatologic Treatments and Research
- Nail Diseases and Treatments
- Ethnobotanical and Medicinal Plants Studies
- Essential Oils and Antimicrobial Activity
- Contact Dermatitis and Allergies
- Eosinophilic Esophagitis
- Eosinophilic Disorders and Syndromes
- Botany, Ecology, and Taxonomy Studies
- Plant Physiology and Cultivation Studies
- Autoimmune Bullous Skin Diseases
- Nonmelanoma Skin Cancer Studies
- Allelopathy and phytotoxic interactions
- Systemic Sclerosis and Related Diseases
- Genetic and rare skin diseases.
- Skin Diseases and Diabetes
- Chemical synthesis and alkaloids
- Plant-based Medicinal Research
- Powdery Mildew Fungal Diseases
- Hepatitis B Virus Studies
- Biological Control of Invasive Species
- Wound Healing and Treatments
- Bacillus and Francisella bacterial research
- Botanical Research and Chemistry
University of South Carolina
2025
Medical University of South Carolina
2023-2024
Spartanburg Regional Medical Center
2024
New York Medical College
2024
FWRadiology
2000-2023
Yale University
1998-2003
Kansas State University
1998-2001
Wilford Hall Ambulatory Surgical Center
2000
Ireland Army Community Hospital
1998-1999
Mayo Clinic
1991-1998
Twenty malaria-naive volunteers received a recombinant Plasmodium falciparum malaria vaccine (RTS,S) containing 19 NANP repeats and the carboxy terminus (amino acids 210-398) of circumsporozoite (CS) antigen coexpressed in yeast with hepatitis B surface antigen. Ten adjuvanted alum, 10 alum plus 3-deacylated monophosphoryl lipid A (MPL). Both formulations were well tolerated immunogenic. MPL enhanced CS antibody levels (measured by ELISA, immunofluorescence, inhibition sporozoite invasion...
Localization of eosinophil granule major basic protein by immunofluorescence permits recognition both infiltration and degranulation. Over the past decade a half, our laboratory has shown that degranulation occur in many diseased tissues humans; among normal studied as controls, only gut showed striking Using an indirect procedure for detection protein, we extended analyses human to include from essentially all body organs; total 117 biopsy/ autopsy specimens were analyzed. To determine...
Reducing morbidity and mortality from malignant melanoma is the greatest challenge facing dermatology today. We present a comparison of Glasgow seven‐point checklist American Cancer Society's ABCDs pigmented lesions for detecting early melanomas. Logistic regression analysis showed that (N = 205 lesions) contained two significant variables (irregular outline, P .001, relative odds 20.9; diameter greater than 1 cm , .005, 6.7) differentiating benign whereas three‐point version 192 had three...
To determine the characteristics of clinical illness accompanying Plasmodium falciparum infection induced by controlled exposure to infected mosquitoes, records 118 volunteers participating in studies conducted between 1985 and 1992 were reviewed. One hundred fourteen (97%) reported at least one symptom attributable malaria, with fatigue, myalgias or arthralgias, headache, chills most commonly reported. The median duration symptoms was 3 days. Fever recorded 61% volunteers; 4 had...
Often consumed for its nutritious benefits, celery (Apium graveolens) contains furocoumarins and psoralens that have photosensitizing properties can induce phytophotodermatitis (PPD) when exposed to UV light. Clinical manifestations of PPD include an eruption vesicles in sun-exposed areas. When as part a typical diet, the amount generally is insufficient PPD; however, individuals who regularly handle or consume produce infected with fungus well those use tanning beds are at increased risk...
Dermatologists may evaluate patients with African trypanosomiasis. The currently available dermatologic literature does not review the cutaneous manifestations of trypanosomiasis.We describe an American man who acquired trypanosomiasis while hunting in Tanzania, and we classify findings this disease. This article reports results first biopsy a trypanid depicts trypanosomes on touch preparation done from specimen. Rare color photographs trypanids are shown.Recognition unique allow...
Background. Immediate reconstruction is the preferred approach to management of defects following Mohs micrographic surgery. In a minority patients, however, contraindicated, and long-term biological dressing that stimulates wound healing minimizes care desirable. Objective. We wanted assess utility lyophilized, type I bovine collagen matrix (SkinTemp) in Methods. Fifteen patients were treated with Study wounds evaluated for time complete granulation, epithelialization, adverse reactions...
Cutaneous depigmentation afflicts millions of people worldwide. For example, vitiligo affects an estimated 1% Americans' and 0.38% to 1.13% individuals 2 Although some patients may respond treatment with topical corticosteroids or oral psoralen plus UV-A (PUVA), 5 many do not, therefore, they seek additional therapy. Several surgical procedures have been devised repigment depigmented skin. 6 These include the transfer autologous melanocytes derived from split-thickness skin grafts, 7...
Dermatitis herpetiformis (DH) is seen most commonly as a pruritic, papulovesicular eruption in young children or adolescents. Differentiation from other bullous diseases of childhood may be difficult. We report the first case an adolescent whom palmar, purpuric macules and papules were only manifestations DH. The patient later developed typical vesiculobullous extensor lesions symptomatic gluten-sensitive enteropathy (GSE). All GSE symptoms resolved with dapsone gluten-free diet. Our purpose...
The cyanobacterium Lyngbya majuscula grows in marine and estuarine environments across the world produces many biologically active compounds.Direct contact with L its dermatoxins can cause seaweed dermatitis, which manifests as a papulovesicular eruption.As oceans warm, will bloom more frequently; therefore, public awareness of dermatitis oceanside communities help promote precautions that reduce risk for exposure.This article describes irritants lead to clinical presentation, prevention...
<h3>REPORT OF CASES</h3><h3>CASE 1</h3> In November 1989, a 60-year-old white man with 2-year history of chronic lymphocytic leukemia presented 1-week pain in both feet accompanied by progressive purpura and petechiae the lower extremities. Purpura over lateral malleoli right medial tibia ulcerated during next 2 weeks (<b>Figure 1</b>, top). A skin biopsy specimen purpuric lesion revealed vascular occlusion amorphous, eosinophilic material that was periodic acid Schiff—positive, diastase...
We present a 42-year-old woman with primary Sjögren's syndrome and polyclonal gammopathy who presented pretibial petechiae, purpura, tender indurated plaques. The plaques revealed lobular plasma cell panniculitis, thus should be added to the short list of collagen vascular diseases that can as panniculitis. Her biopsies also demonstrated intense perieccrine infiltrates may account for syndrome-associated hypohidrosis. observed occasional occlusion vessels an amorphous, eosinophilic material...