- Protein Degradation and Inhibitors
- Electrocatalysts for Energy Conversion
- Advanced battery technologies research
- Catalytic Processes in Materials Science
- Supercapacitor Materials and Fabrication
- Fuel Cells and Related Materials
- Semiconductor Quantum Structures and Devices
- Electrodeposition and Electroless Coatings
- Conducting polymers and applications
- Catalysts for Methane Reforming
- Semiconductor materials and devices
- Electrochemical Analysis and Applications
- Advancements in Battery Materials
- Advanced Photocatalysis Techniques
- Nanoporous metals and alloys
- Electrochemical sensors and biosensors
- Advanced biosensing and bioanalysis techniques
- Advanced Semiconductor Detectors and Materials
- Multiple Myeloma Research and Treatments
- HIV/AIDS drug development and treatment
- Quantum Dots Synthesis And Properties
- Glioma Diagnosis and Treatment
- Click Chemistry and Applications
- Gas Sensing Nanomaterials and Sensors
- Advanced Battery Materials and Technologies
Sungkyunkwan University
2016-2025
LG Chem (South Korea)
2022
Institute of Physics, Academia Sinica
2021
Suwon Research Institute
2014-2019
Government of the Republic of Korea
2016-2019
Seoul National University
1992-2013
University of Connecticut
1992-2005
Bio-Medical Science (South Korea)
2003-2005
Electronics and Telecommunications Research Institute
2003-2004
National Sun Yat-sen University
2002
We have isolated a new type of ATP-dependent protease from Escherichia coli. It is the product heat-shock locus hslVU that encodes two proteins: HslV, 19-kDa protein similar to proteasome beta subunits, and HslU, 50-kDa related ATPase ClpX. In presence ATP, hydrolyzes rapidly fluorogenic peptide Z-Gly-Gly-Leu-AMC very slowly certain other chymotrypsin substrates. This activity increased 10-fold in E. coli expressing proteins constitutively 100-fold cells HslV HslU high copy plasmid. Although...
In addition to protease La (the lon gene product), Escherichia coli contains another ATP-dependent protease, Ti. This enzyme (approximately 340 kDa) is composed of two components, both which are required for proteolysis. Both have been purified homogeneity by conventional procedures using [3H]casein as the substrate. The ATP-stabilized component, A, has a subunit molecular weight 80,000 upon gel electrophoresis in presence sodium dodecyl sulfate, but it behaves dimer (140 filtration....
Abstract Functional groups in two‐dimensional (2D) Ti 3 C 2 T x MXene are an important factor influencing electrochemical performance many applications involving energy storage, sensors, and water purification. However, after dimethyl sulfoxide (DMSO) delamination, the effect of surface functionalities is still unclear there no systematic reports on its capacitive behavior. Experiments theoretical calculations confirm relationship between different functionalities, DMSO delamination effect,...
Exploration of novel single or Z-scheme based composite photocatalysts is pursued for solar–chemical energy conversion.
The energy requirement for protein breakdown in Escherichia coli has generally been attributed to the ATP-dependence of protease La, lon gene product. We have partially purified another ATP-dependent from lon-cells that lack La (as shown by immunoblotting). This enzyme hydrolyzes [3H]methyl-casein acid-soluble products presence ATP and Mg2+. hydrolysis appears necessary proteolytic activity. Since this is inhibited diisopropyl fluorophosphate, it be a serine protease, but also contains...
Protease Ti, a new ATP-dependent protease in Escherichia coli, degrades proteins and ATP linked process, but these two hydrolytic functions are catalyzed by distinct components of the enzyme. To clarify enzyme's specificity role ATP, variety fluorogenic peptides were tested as possible substrates for Ti or its components. rapidly hydrolyzed N-succinyl(Suc)-Leu-Tyr-amidomethylcoumarin (AMC) (Km = 1.3 mM) which is not degraded La, other E. coli. also hydrolyzed, slowly, Suc-Ala-Ala-Phe-AMC...
Abstract Functional materials with attractive electronic and photoelectronic properties show great promise in various fields. In recent decades, tremendous research efforts have been devoted to the design of photoactive electroactive for qualitative quantitative analysis environmental pollutants. This review gives a concise overview on fundamentals progress functional material‐based electrochemical photoelectrochemical technology pollutant monitoring. The rational promoted basic signaling...
Abstract Electrochemical CO 2 reduction reaction (CO RR) to produce value‐added multi‐carbon chemicals has been an appealing approach achieving environmentally friendly carbon neutrality in recent years. Despite extensive research focusing on the use of high‐value like high‐energy‐density hydrocarbons, there have few reports production propane (C 3 H 8 ), which requires chain elongation and protonation. A rationally designed 0D/2D hybrid Cu O anchored‐Ti C T x MXene catalyst (Cu O/MXene) is...
Incorporation of MOFs into COF pores (IL@MC QSSE) greatly facilitates lithium-ion transport for outstanding cycling performance Li metal batteries.
The product of the lon gene in Escherichia coli is an ATP-dependent protease, protease La, that also binds strongly to DNA. Addition double-stranded or single-stranded DNA presence ATP was found stimulate hydrolysis casein globin 2- 7-fold, depending on concentration. Native from several sources (plasmid pBR322, phage T7, calf thymus) had similar effects, but after denaturation 20-100% more effective than native form. Although poly(rA), mRNA, and various tRNAs did not proteolysis, poly(rC)...