About
Contact & Profiles
A5025690605
Research Areas
- Cancer Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Extracellular vesicles in disease
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Bone health and treatments
Hunan Cancer Hospital
2024
Central South University
2024
Tumor-associated macrophages of the M2 phenotype promote cancer initiation and progression. Importantly, macrophage-derived exosomes play key roles in malignancy cells. Here, we report that circTMCO3 is upregulated ovarian patients, its high expression indicates poor survival. M2-derived proliferation, migration, invasion cancer, but these effects are abolished by knockdown circTMCO3. Furthermore, functions as a competing endogenous RNA for miR-515-5p to reduce abundance, thus upregulating...
10.1038/s42003-024-06095-8
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cc-by
Communications Biology
2024-05-16
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