Pradeep Madhamanchi

ORCID: 0000-0003-2818-4502
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About
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Research Areas
  • Genomics, phytochemicals, and oxidative stress
  • Autophagy in Disease and Therapy
  • Nuclear Receptors and Signaling
  • Piperaceae Chemical and Biological Studies
  • Neuroscience and Neuropharmacology Research
  • PI3K/AKT/mTOR signaling in cancer
  • Epilepsy research and treatment
  • Cancer Mechanisms and Therapy
  • RNA regulation and disease
  • Endoplasmic Reticulum Stress and Disease
  • Ion channel regulation and function
  • Ubiquitin and proteasome pathways
  • Amyotrophic Lateral Sclerosis Research

University of Hyderabad
2022-2023

Sri Gokulam Hospital
2023

Epileptic seizures occur due to an imbalance between excitatory and inhibitory neurosignals. The excitotoxic insults promote the accumulation of reactive oxygen species (ROS), unfolded proteins (UFP) aggregation, sometimes even cell death. epileptic brain samples in our study showed significant changes quantity UFP accumulation. This part explored efficiency ER stress autophagy responses at neutralizing using resected tissue samples. Meanwhile, we regularly observed these patients'...

10.1007/s12192-022-01301-0 article EN cc-by-nc-nd Cell Stress and Chaperones 2022-10-18
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