A5083425673- Sleep and Wakefulness Research
- Circadian rhythm and melatonin
- Neuroscience of respiration and sleep
- Neural dynamics and brain function
- Sleep and related disorders
- Neuroscience and Neuropharmacology Research
- Regulation of Appetite and Obesity
- Neuroendocrine regulation and behavior
- Zebrafish Biomedical Research Applications
- Neurobiology and Insect Physiology Research
University of California, Los Angeles
2021-2024
University of Bern
2020-2021
University Hospital of Bern
2017-2021
University of Szeged
2020-2021
The anterior cingulate cortex (ACC) is believed to play a key role in reward-based learning uncertain and dynamic environments. Recent work suggests that these environments, ACC neurons monitor decisions their outcomes inform behavioral strategy. Yet, it remains unclear whether similarly encode history fully deterministic perceptual decision-making tasks and, if so, how signals interact with other are represented by neurons. Here, we recorded the activity of freely moving mice performing...
The lateral hypothalamus (LH), together with multiple neuromodulatory systems of the brain, such as dorsal raphe nucleus (DR), is implicated in arousal, yet interactions between these are just beginning to be explored. Using a combination viral tracing, circuit mapping, electrophysiological recordings from identified neurons, and combinatorial optogenetics mice, we show that GABAergic neurons LH selectively inhibit DR, resulting increased firing substantial fraction its ultimately promotes...
Significance The lateral hypothalamus encompasses neural circuits that are highly active during feeding behavior and rapid eye movement sleep. Yet, it remains unclear whether these mutually exclusive behaviors share common populations. Here, we recorded perturbed the activity of inhibitory neurons (LH) across sleep in freely behaving mice. We found is reliably encoded by specific patterns neuron reactivated Disrupting specifically decreased subsequent behavior. These results suggest...
ABSTRACT The lateral hypothalamus (LH), together with multiple neuromodulatory systems of the brain, such as dorsal raphé nucleus (DR), is implicated in arousal, yet interactions between these are just beginning to be explored. Using a combination viral tracing, circuit mapping, electrophysiological recordings from identified neurons and combinatorial optogenetics mice, we show that GABAergic LH selectively inhibit DR resulting increased firing substantial fraction its ultimately promotes...