A5028729289- Cancer Treatment and Pharmacology
- Pharmacological Effects of Medicinal Plants
- Pharmacological Effects of Natural Compounds
- Cynara cardunculus studies
- Nutrition and Health in Aging
- Phytochemicals and Antioxidant Activities
- Silymarin and Mushroom Poisoning
- Diet and metabolism studies
- Natural Antidiabetic Agents Studies
- Bone health and osteoporosis research
- Herbal Medicine Research Studies
- Complementary and Alternative Medicine Studies
- Pharmacology and Obesity Treatment
- Phytoestrogen effects and research
- Cancer therapeutics and mechanisms
- Essential Oils and Antimicrobial Activity
- Berberine and alkaloids research
- Antioxidant Activity and Oxidative Stress
- Bee Products Chemical Analysis
- Pomegranate: compositions and health benefits
- Ginseng Biological Effects and Applications
- Animal Nutrition and Physiology
- Curcumin's Biomedical Applications
- Biochemical Analysis and Sensing Techniques
- Microtubule and mitosis dynamics
University of Genoa
2023-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2023-2024
Istituto Giannina Gaslini
2023-2024
Indena (Italy)
2014-2023
Indena (France)
2000-2021
University of Pavia
2021
University College of Bahrain
2021
University of Bahrain
2021
Université Gustave Eiffel
2020
University of Urbino
2007
The importance of quercetin and flavonoids in the diet as food supplements is well known, literature studies support their potential use to treat several human diseases. Many beneficial properties have been described for quercetin, so much effort has directed into overcoming major drawbacks this natural compound—its poor solubility low oral absorption. aims study were compare a new food-grade lecithin-based formulation Quercetin Phytosome®, unformulated terms simulated gastrointestinal...
Background: Quercetin, a well-known naturally occurring polyphenol, has recently been shown by molecular docking, in vitro and vivo studies to be possible anti-COVID-19 candidate. Quercetin strong antioxidant, anti-inflammatory, immunomodulatory, antiviral properties, it is characterized very high safety profile, exerted animals humans. Like most other polyphenols, quercetin shows low rate of oral absorption its clinical use considered modest utility. delivery-food grade system with...
Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of ongoing global pandemic known as COVID-19. Based on potential antiviral role quercetin, and its described anti-blood clotting, anti-inflammatory antioxidant properties, we hypothesize that subjects with mild COVID-19 treated Quercetin Phytosome ® (QP), a novel bioavailable form may have shorter time to virus clearance, milder symptomatology, higher probabilities benign earlier resolution disease....
This double-blind, randomized study was aimed at evaluating comparatively, in postmenopausal women, the activity of a standardized soy extract (SOYSELECT) and placebo when given alone or combination with conjugated equine estrogens (CEE) on early climacteric symptoms. Lipid profile, pituitary hormones, osteocalcin endothelin levels, vaginal endometrial parameters were also evaluated.Participants control group placebo, participants treated 400 mg/day extract, corresponding to 50 mg/daily...
The aim of this study was to evaluate the performance Edmonton Frail Scale (EFS) on frailty assessment in association with multi-dimensional conditions assessed specific screening tools and explore prevalence by gender. We enrolled 366 hospitalised patients (women\men: 251\115), mean age 81.5 years. EFS given their frailty. Then we collected data concerning cognitive status through Mini-Mental State Examination (MMSE), health (evaluated number diseases), functional independence (Barthel...
Chronic kidney disease (CKD) subjects suffer from high risk of cardiovascular mortality, and any intervention preventing the progression CKD may have an enormous impact on public health. In last decade, there has been growing awareness that gut microbiota (GM) can play a pivotal role in controlling pathogenesis systemic inflammatory state progression. To ameliorate quality life subjects, use dietary supplements increased over time. Among those, curcumin demonstrated significant vitro...
Background: Quercetin, a natural polyphenol with demonstrated broad-spectrum antiviral, anti-inflammatory, and antioxidant properties, has been proposed as an adjuvant for early-stage coronavirus disease 2019 (COVID-19) infection. Objective: To explore the possible therapeutic effect of quercetin in outpatients mild to moderate symptoms COVID-19. Methods: This was open-label randomized controlled clinical trial conducted at department medicine, King Edward Medical University, Lahore, PK....
Hyperlipemia represents an independent risk factor in the development of atherosclerosis patients undergoing type 2 diabetes mellitus (DM). Moreover, pharmacological treatment dyslipemia DM (e.g. by means statins), is accompanied relevant side effects and oral supplementation with natural antioxidants, such as Citrus polyphenols, has recently been suggested to improve cardioprotection patients. However, due poor gastrointestinal absorption novel formulations have developed for getting a...
Epidemiologic data support an inverse association between green tea intake and breast cancer risk. Greenselect Phytosome (GSP) is a lecithin formulation of caffeine-free catechin extract. The purpose the study was to determine tissue distribution epigallocatechin-3-O-gallate (EGCG) its effect on cell proliferation circulating biomarkers in patients. Twelve early patients received GSP 300 mg, equivalent 44.9 mg EGCG, daily for 4 weeks prior surgery. EGCG levels were measured before (free)...
The evidence regarding a deficiency of manganese (Mn) in humans is scarce. So the aim this narrative review was to consider state art on relation between and bone health effectiveness supplementation (alone or with other micronutrients) mineralization. This included 4 eligible studies. All literature published agreement showing that osteoporotic women have lower serum Mn levels than normal mineral density, thus confirming essential role synthesis cartilage collagen, as well mineralization...
Quercetin, for its crucial properties, fulfills the need a multifactor action that is useful potential counterbalance of COVID-19 infection. Given this background, aim study was to evaluate effect 3 months' supplementation with Quercetin Phytosome® (250 mg twice day) as prevention against symptomatic COVID-19. In total, 120 subjects were enrolled (males, 63; females, 57; age 49 ± 12), 60 in group and placebo group. No significant differences detected between groups terms gender, smoking,...