A5001184242- Nonmelanoma Skin Cancer Studies
- Reconstructive Facial Surgery Techniques
- Reconstructive Surgery and Microvascular Techniques
- Cancer and Skin Lesions
- Cutaneous Melanoma Detection and Management
- Cutaneous lymphoproliferative disorders research
- Medicine and Dermatology Studies History
- Dermatologic Treatments and Research
- Nail Diseases and Treatments
- Surgical Sutures and Adhesives
- Infectious Diseases and Mycology
- Vascular Tumors and Angiosarcomas
- Tumors and Oncological Cases
- Hair Growth and Disorders
- Wound Healing and Treatments
- Psoriasis: Treatment and Pathogenesis
- Facial Rejuvenation and Surgery Techniques
- Ear and Head Tumors
- Retinoids in leukemia and cellular processes
- Head and Neck Surgical Oncology
- Dupuytren's Contracture and Treatments
- Nasal Surgery and Airway Studies
- Oral and Maxillofacial Pathology
- Genetic and rare skin diseases.
- Skin Protection and Aging
British Cardiovascular Society
2024
Georgetown University Medical Center
2023
Georgetown University
2023
Vince Lombardi Cancer Clinic
2023
Oregon Health & Science University
2005-2021
Leo Pharma (Denmark)
2012
University of Portland
2009
Oregon Medical Research Center
2004
University of Iowa
2004
University of Massachusetts Boston
1996
Actinic keratosis is a common precursor to sun-related squamous-cell carcinoma. Treating actinic keratoses and the surrounding skin area (i.e., field therapy) can eradicate clinical subclinical keratoses. Topical therapy currently requires weeks or months of treatment. We investigated efficacy safety new topical for keratosis, ingenol mebutate gel (0.015% face scalp 0.05% trunk extremities).In four multicenter, randomized, double-blind studies, we randomly assigned patients with on...
• Each year, it is estimated, more than 500,000 new cases of nonmelanoma skin cancer develop.<sup>1-3</sup>The majority these cutaneous neoplasms are treated by various modalities that include excision,<sup>4-6</sup>electrodesiccation and curettage,<sup>7-9</sup>cryosurgery,<sup>10,11</sup>and irradiation,<sup>12,13</sup>with greater 90% success.<sup>3,14,15</sup>Certain the remaining primary tumors, as well recurrent carcinomas, present a demanding therapeutic challenge. For lesions, Mohs...
A new botulinum toxin type (BoNT-A) has been assessed in the United States for treatment of glabellar lines. In April 2009, US FDA approved Biologics License Application a formulation BoNT-A (Dysport [abobotulinum A]; Medicis Aesthetics Inc., Scottsdale, AZ).To compare efficacy and safety single with placebo subjects moderate to severe lines.One hundred fifty-eight lines were randomized 2:1 receive 50 U (n=105) or (n=53). Responders defined as having no mild at 30 days posttreatment...
The process of wound healing can be divided into substrate, proliferative, and remodeling phases. basic biologic physiologic events which transpire during these stages are examined in detail. Particular emphasis is placed on the interactions between platelets, macrophages, other inflammatory cells, fibroblasts wound. Recent advances roles played by interleukins, fibronectin, epidermal growth factor discussed.
There is evidence suggesting a role of eicosanoids in the growth certain tumors. In this study, tissue samples were collected from basal cell carcinomas (BCCs) and squamous (SCCs) skin. Both BCCs SCCs contained more prostaglandin E2 F2 alpha (PGE2 PGF2 alpha) than normal epidermis. vitro incubation tumor with arachidonic acid also resulted PGE2 formation. Basal exhibiting histologically aggressive pattern higher levels prostaglandins those nonaggressive pattern, both vivo after incubation....
It remains questionable whether micrographic surgery with frozen sections is an appropriate technique for excision of melanoma in situ (MIS) the lentigo maligna type. Advocates have interpreted MIS as being histologically defined by nests and contiguous atypical melanocytes on basal layer. Others, however, viewed periphery consisting scattered single melanocytes, a finding that may be difficult or impossible to establish sections.To examine reliability using experienced Mohs' surgeon,...
Abstract. Fibrous tumors of the soft tissue are usually benign, but some fibrous neoplasms such as dermatofibrosarcoma protuberans (DFSP), atypical fibroxanthoma (AFX), and malignant fibrohistiocytoma (MFH) can be very destructive locally with a high recurrence rate after local excision. On occasion, they metastasize. Previous reports have confirmed success Mohs micrographic surgery for treatment DFSP, data been lacking on potential benefit this surgical approach MFH AFX tumors. Over past 6...
Tissue expansion is indicated in the reconstruction of various defects head and neck instances where there inadequate adjacent tissue to allow either primary closure defect or repair with a local flap. It may also be by an alternative method such as local, regional, distant flap will result unacceptable donor recipient site deformity. Although simplistic concept, it does require judgment indepth preoperative planning ensure optimal results. The complication rate high for neck, particularly...
Penile tumors represent a difficult group of neoplasms requiring effective and curative treatment while minimizing tissue loss to prevent cosmetic functional deformity. Over the past 6 years, we have treated 20 patients with penile cancer utilizing fresh technique Mohs micrographic surgery. Tumors were excised an average 2.25 stages. Most defects (80%) allowed heal by second intention. Since surgery, four developed metastatic disease in their regional lymphatic system, one patient has died...
Abstract. Two cases of treatment site granulomatous reaction to Zyderm Collagen Implant that occurred in spite a negative skin test are reported. A delayed hypersensitivity ZCI is suggested by the clinical time course and histologic findings granulomas. Humoral immunity also implicated since elevated anti‐Zyderm serum antibodies plasma cell infiltrates present. Resolution signs symptoms over several months with no treatment. The physician using should be aware this rare adverse reaction.