A5102792816- Animal Disease Management and Epidemiology
- Animal Virus Infections Studies
- Viral Infections and Immunology Research
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Graph Labeling and Dimension Problems
- RNA and protein synthesis mechanisms
- Advanced Graph Theory Research
- Anesthesia and Neurotoxicity Research
- Opioid Use Disorder Treatment
- Vector-Borne Animal Diseases
- RNA modifications and cancer
- Graph theory and applications
- Plant Ecology and Taxonomy Studies
- interferon and immune responses
- Plant Pathogens and Resistance
- Fungal Biology and Applications
- Respiratory viral infections research
- Influenza Virus Research Studies
- graph theory and CDMA systems
- RNA regulation and disease
- Mercury impact and mitigation studies
- Phytochemistry and Biological Activities
- Potato Plant Research
- Bee Products Chemical Analysis
Nanjing Agricultural University
2019-2023
China Medical University
2011-2020
Affiliated Hospital of Guizhou Medical University
2020
Guiyang Medical University
2020
Buchang Pharma (China)
2018
National Cheng Kung University
2006
National Cheng Kung University Hospital
2006
UVA irradiation induced ROS-mediated photo damage to the human skin leading coarseness, wrinkling, pigmentation, and cutaneous malignancies. We investigated dermatoprotective efficacies of submicromolar concentrations ergothioneine (EGT, 0.125-0.5 μM), which occurs naturally as a sulfur-containing amino acid, in mechanisms fibroblast (HSF) cells. UVA-induced AP-1 (c-Fos c-Jun) translocation was found be inhibited by EGT treatments with parallel inhibition collagenolytic matrix...
To determine the association between rainfall rate and occurrence of enterovirus infection related to contamination drinking water.One fatality case three cases severe illness were observed during epidemic in a village southern Taiwan from 16 September 3 October 1998. Groundwater samples collected public well after heavy test for using reverse transcription-polymerase chain reaction (RT-PCR) assay. The RT-PCR assay detected groundwater sample on 26 logistic regression model also revealed...
Alphaviruses threaten public health continuously, and Getah virus (GETV) is a re-emerging alphavirus that can potentially infect humans. Approved antiviral drugs vaccines against alphaviruses are few available, but several host factors have been reported. Here, we used GETV as model of to screen for additional factors. Tetrachlorodibenzo-p-dioxin-inducible poly(ADP ribose) polymerase was identified inhibit replication by inducing ubiquitination the glycoprotein E2, causing its degradation...
Novel H7N9 influenza virus transmitted from birds to human and, since March 2013, it has caused five epidemic waves in China. Although the evolution of viruses been investigated, evolutionary changes associated with codon usage are still unclear. Herein, pattern two surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA), was studied understand relation host, wave, pathogenicity. Both genes displayed a low bias, HA higher than NA. The driven by mutation pressure natural selection,...
Background: Since 1998, Taiwan has experienced annual outbreaks of enterovirus 71 (EV71) nationwide. The area around Taichung City a particularly large outbreak in 2005, after which EV71 disappeared for 2 y before re-emerging 2008. Here we present the clinical, genotypic, and epidemiological baseline data 2005 outbreak. Methods: Throat swab, stool cerebrospinal fluid samples were collected stored viral transport medium. Samples tested by reverse-transcriptase polymerase chain reaction...
Codonopsis taxa, as a traditional Chinese medicinal and edible plant, has found expanding domestic foreign applications in recent decades. However, the poor management germplasm resources market inevitably caused an unnecessary hybrid of provenances. In order to clarify characteristics main production area, cultivars collected from provinces Gansu, Shannxi, Shanxi, Hubei China were researched, using internal transcribed spacer (ITS) sequence technology. The confirmation additive nucleotides...
Background: A key challenge in the process of virus amplification is need for a simple and convenient method measuring titers. Objective: Real-time unlabeled cell analysis (RTCA) was used to establish standard curve correlation between half-cell index time (CIT50) titer. At same time, titer from tunable resistance pulse detection (TRPS) technology compared with traditional median tissue culture infectious dose (TCID50) evaluate feasibility application value RTCA technique TRPS technology....
Canine parvovirus type 2 (CPV-2) is a severe enteric pathogen mainly affecting dogs. CPV-2 contains three antigenic variants (2a, 2b, and 2c) that are distributed internationally. Detection characterization of the currently circulating strains vital for understanding viral evolution, transmission, development methods to control its spreading. Herein, we analyzed in central Taiwan provide information local diversity, epidemiology. Stool blood samples from 24 dogs cats were genotyped by PCR...