A5021279149- Prostate Cancer Treatment and Research
- Cancer, Lipids, and Metabolism
- Melanoma and MAPK Pathways
- Prostate Cancer Diagnosis and Treatment
- Estrogen and related hormone effects
- Microbial Natural Products and Biosynthesis
- Ubiquitin and proteasome pathways
- Plant biochemistry and biosynthesis
- Cell Adhesion Molecules Research
- Steroid Chemistry and Biochemistry
- Lung Cancer Treatments and Mutations
- Cancer-related Molecular Pathways
- Sexual Differentiation and Disorders
- Cancer Mechanisms and Therapy
- Radiopharmaceutical Chemistry and Applications
- Vaccine Coverage and Hesitancy
- Genomics and Rare Diseases
- Dermatology and Skin Diseases
- Nuclear Structure and Function
- PARP inhibition in cancer therapy
- Biochemical and Structural Characterization
- Neurofibromatosis and Schwannoma Cases
- Patient-Provider Communication in Healthcare
- Genetics and Neurodevelopmental Disorders
- Bladder and Urothelial Cancer Treatments
Chinese University of Hong Kong
2025
University of Hong Kong
2017-2025
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
2022
Hong Kong University of Science and Technology
2017-2022
Precision Therapeutics (United States)
2015
Cancer Research UK Scotland Institute
2012
Institute of Cancer Research
2012
Southern General Hospital
2012
NHS Greater Glasgow and Clyde
2011
Gartnavel General Hospital
2011
Abstract Neurodevelopmental disorders (NDDs) often have unknown genetic causes. Current efforts in identifying disease-related variants using exome or genome sequencing still lead to an excessive number of uncertain significance (VUS). There is increasing interest transcriptomics and, more recently, proteomics for variant detection and interpretation. In this study, we integrated quantitative liquid chromatography-mass spectrometry proteomics, RNA sequencing, reanalysis resolve VUS detect...
Research on allergy has recently uncovered an apparent co-occurrence of allergies in skin and the lungs, a phenomenon that been coined “atopic march”. A positive correlation found between gut microbiota at birth development asthma eczema later life. Chinese medicine long described functional relationship large intestine lungs skin. In this short article, we examined evidence support these inter-organ physiological/pathological relationships. addition to clinical observation composition...
Introduction. The family of fibroblast growth factor (FGF) and their receptors (FGFRs) play a critical role in nervous system development. Aberrant expression or change the pattern may contribute to neural tumour formation. FGFR status vestibular schwannoma is unknown. Aim. To characterize FGFR-1, FGFR-3 FGFR-4 resection schwannoma. Method. Fifty paraffin-embedded archival specimens schwannomas were immunostained fro using specific rabbit polyclonal antibodies. signals graded as weak,...
Abstract Introduction Early diagnosis is critical in reducing mortality prostate cancer. The extant literature identifies a range of variables which impact on when men present primary care. For example, recent evidence suggests that from high deprivation areas are significantly more likely to with advanced disease and have lower survival rates. Psychosocial theories provide framework for understanding patterns the timing diagnoses, role social context relationships help-seeking behaviour....
RAC 3, one of the p160 family co-activators is known to enhance transcriptional activity a number steroid receptors. As are also androgen receptor (AR) activity, we investigated role 3 in context prostate cancer. In cancer cell lines, found variable levels protein with highest expression seen AR-positive LNCaP cells, moderate AR-negative PC cells and low-level DU 145 cells. Immuno-precipitation studies showed that endogenous interacted AR vivo transfection assays confirmed enhanced activity....