A5061026391- Tuberculosis Research and Epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment
- Hepatitis B Virus Studies
- Viral Infections and Outbreaks Research
- Disaster Response and Management
- Clostridium difficile and Clostridium perfringens research
- HIV/AIDS drug development and treatment
- Orthopedic Infections and Treatments
- Diagnosis and treatment of tuberculosis
- Hepatitis Viruses Studies and Epidemiology
- Antibiotics Pharmacokinetics and Efficacy
- Microscopic Colitis
- Antimicrobial Resistance in Staphylococcus
- Mycobacterium research and diagnosis
- Diabetic Foot Ulcer Assessment and Management
- Surgical site infection prevention
- Vaccine Coverage and Hesitancy
- Body Image and Dysmorphia Studies
- Hepatitis C virus research
- Bacterial Identification and Susceptibility Testing
- Burkholderia infections and melioidosis
- Head and Neck Cancer Studies
- Colorectal and Anal Carcinomas
- Sepsis Diagnosis and Treatment
- Healthcare Systems and Technology
Leicester Royal Infirmary
2010-2023
University Hospitals of Leicester NHS Trust
2011-2022
Welsh Ambulance Services NHS Trust
2022
University of Leicester
2016-2022
Government of the United Kingdom
2021
Government of Western Australia Department of Health
2017
Royal Darwin Hospital
2009
University of Wales
2003
Journal Article Lassa fever Epidemiological aspects of the 1970 epidemic, Jos, Nigeria Get access D.E. Carey, Carey * Virus Research Laboratory, University Ibadan *Present address: Laconia Clinic, 724 Main Street, Laconia, New Hampshire, 03246, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar G.E. Kemp, Kemp H.A. White, White Evangel Hospital, Sudan Interior Mission, L. Pinneo, Pinneo R.F. Addy, Addy Ministry Health, Benue Plateau State A.L.M.D. Fom, Fom G....
Journal Article Lassa fever A study of 23 hospital cases Get access H.A. White Evangel Hospital, Sudan Interior Mission, Jos, Nigeria Search for other works by this author on: Oxford Academic PubMed Google Scholar Transactions The Royal Society Tropical Medicine and Hygiene, Volume 66, Issue 3, 1972, Pages 390–398, https://doi.org/10.1016/0035-9203(72)90269-6 Published: 01 January 1972
The clinical and histopathological findings (excluding the central nervous system) are described in two patients who died of Lassa fever. changes somewhat similar to those Thai Bolivian haemorrhagic fevers. It is considered that virus yet another cause "haemorrhagic fever".
ObjectivesWe describe failure rates of 198 patients with bone and joint infection (BJI), including prosthetic diabetic foot osteomyelitis, managed through the Glasgow centre for outpatient parenteral antibiotic therapy (OPAT) over a period 4 years. Outcomes following initial intravenous antimicrobial median follow-up time 60 weeks are described.
In mid-January 1970 a number of patients entered Evangel Hospital at Jos, Nigeria, with severe, acute febrile illness, clinically similar to cases Lassa fever as first seen Jos in February 1969. By mid-February there were 26 suspected cases, some them mild, 10 deaths. The (17 females, nine males) aged 5 months 46 years; all but one Nigerians. Additional Nigerian Vom Christian Hospital, 13 miles from Jos. Isolation virus was not attempted. Eleven and two provisionally confirmed by...
Osteoarticular infections are a primary indication for outpatient parenteral antimicrobial therapy (OPAT). The climate and geographical diversity of tropical Australia, together with the prevalence melioidosis, disseminated gonococcal disease community-acquired methicillin-resistant Staphylococcus aureus renders this challenging environment in which to manage such infections. We evaluated patients managed by Royal Darwin Hospital Home service bone joint infections.A retrospective analysis...
Background: Screening and treatment for latent tuberculosis infection (LTBI) are key TB control. In the UK, National Institute Health Care Excellence (NICE) British HIV Association (BHIVA) give conflicting guidance on which groups of people with (PWH) should be screened, previous national analysis demonstrated heterogeneity in how is applied. There an urgent need a firmer clinical effectiveness evidence base to build screening policy. Methods: We conducted systematic, programmatic...
The University Hospitals of Leicester NHS Trust outpatient parenteral antimicrobial therapy (OPAT) service has expanded rapidly with more nurse-led direction.A retrospective study between 1 July 2014 and 31 December 2019 was undertaken to assess the impact OPAT expansion on beds released for further utilisation, clinical outcomes, adverse vascular access device (VAD) outcome, self- family-administered therapy.Data were extracted from Patient Management System a patient questionnaire...
Abstract Introduction People living with HIV (PLWH) are at high risk of active tuberculosis (TB) but this in the era antiretroviral treatment (ART) remains unclear. It is critical to identify groups who should be prioritised for latent TB (LTBI) screening. In study we identified factors associated developing incident disease, by analysing a 30‐year observational cohort. Methods We evaluated PLWH Leicester, UK, between 1983 and 2017 ascertain those developed timing relation diagnosis; whether...
The incidence of Clostridium difficile infection (CDI) in the UK rose dramatically during early years this century, part associated with emergence hyper-virulent ribotype 027 strain. University Hospitals Leicester (UHL), a 2000-bed acute NHS Trust, implemented number interventions, which led to an 80% reduction new cases over twelve month period. Changes were introduced as result collaboration between Infection Prevention team, departments Microbiology and Infectious Diseases, support Trust...
People living with HIV (PLWH) are at increased risk of re-activation latent tuberculosis infection (LTBI). Although UK and international guidelines identify this group as a priority for LTBI screening treatment, data on attitudes PLWH to policy recommendation lacking.A five-point, Likert-style questionnaire was administered assess views intentions towards accepting treatment. Subsequent interferon-γ release assay (IGRA) testing offered, chemoprophylaxis if required. Influencing demographic...
The distinction between foot and ankle wound healing complications as opposed to infection is crucial for the appropriate efficacious allocation of antibiotic therapy. Multiple reports have focused on diagnostic accuracy different inflammatory markers, however, mainly in diabetic population.To evaluate white cell count (WCC) C-reactive protein (CRP) tools this non-diabetic cohort.Data was reviewed from a prospectively maintained Infectious Diseases Unit database 216 patients admitted at...
Collaboration and service evaluation are essential enablers for improving models of health social care. Significant benefits can be achieved when they combined to form a collaborative evaluation, particularly such collaboration involves different clinical professions.This article uses the NHS 111 Wales explore simple example discuss challenges identified. While tabletop exercises described were expected focus solely on compliance data reasons non-compliance, broader learning was identified...
Introduction: Indigenous people have a fourfold higher incidence of sepsis in the Top End Northern Territory, Australia. However, their mortality from is not higher, despite an overall lower life expectancy, poorer access to healthcare, remoteness, chronic disease burden and social disadvantage. This suggests that patients with receive same standard care as non-Indigenous patients; however, this has been confirmed by investigation. The objective present study was compare early management...
When asked to examine a patient in clinical examination, undergraduates and postgraduates characteristically begin with painstaking observation of the hands. It was concern that this is done mainly for benefit examiners that, routine practice, examination hands receives scant attention. The case notes 70 general medical surgical inpatients were reviewed it found only seven there any mention physical hands; three these "no clubbing" entry. However, when authors carefully examined 197...
Background Hydradenitis suppurativa (HS) is a chronic inflammatory skin disease. The UK prevalence estimated at between 1-4%. There an approximate 3:1 female: male preponderance and it associated with smoking, obesity, type 2 diabetes mellitus. pathogenesis of HS poorly understood. Clinical features vary in extent the axillae, inguinal anogenital areas are typically affected. It has significant impact on quality life, high rates depression amongst sufferers. Current treatment guidelines...