A5024500372- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Parasites and Host Interactions
- Malaria Research and Control
- Viral Infections and Vectors
- Leptospirosis research and findings
- Vector-borne infectious diseases
- Eosinophilic Disorders and Syndromes
- Zoonotic diseases and public health
- Insect and Pesticide Research
- Insect Pest Control Strategies
- Dermatological diseases and infestations
- Mosquito-borne diseases and control
- Parasitic Infections and Diagnostics
- Synthesis and Biological Evaluation
- Vector-Borne Animal Diseases
- Herpesvirus Infections and Treatments
- Poverty, Education, and Child Welfare
- Evolution and Genetic Dynamics
- Global Health and Epidemiology
- Autoimmune Bullous Skin Diseases
- Parasitic Diseases Research and Treatment
- Global Maternal and Child Health
- Toxoplasma gondii Research Studies
- Insects and Parasite Interactions
Drugs for Neglected Diseases Initiative
2016-2025
Real Academia Española
2020-2025
Food and Agriculture Organization of the United Nations
2024
Centro Nacional de Medicina Tropical
2002-2021
Instituto de Salud Carlos III
2000-2021
Escuela Nacional de Sanidad
2004-2017
Research Institute Hospital 12 de Octubre
2017
Universidad Complutense de Madrid
2017
Hospital General Universitario Gregorio Marañón
2017
London School of Hygiene & Tropical Medicine
2015
As part of a World Health Organization-led effort to update the empirical evidence base for leishmaniases, national experts provided leishmaniasis case data last 5 years and information regarding treatment control in their respective countries comprehensive literature review was conducted covering publications on 98 three territories (see 'Leishmaniasis Country Profiles Text S1, S2, S3, S4, S5, S6, S7, S8, S9, S10, S11, S12, S13, S14, S15, S16, S17, S18, S19, S20, S21, S22, S23, S24, S25,...
During the past decade, liposomal amphotericin B has been used with increasing frequency to treat visceral leishmaniasis (VL). The World Health Organization convened a workshop review current knowledge and develop guidelines for use VL. In Europe, is widely Africa Asia, VL disease burden high drug access poor; available only through preferential pricing nonprofit groups in East Africa. Clinical trials experience demonstrate efficacy low toxicity (total dose, 20 mg/kg) immunocompetent...
A study was carried out on the infectivity to sandflies of 16 dogs naturally parasitized by Leishmania infantum. All were seropositive and parasite had been isolated from all except one. They divided into 3 clinical groups: 5 asymptomatic, 4 oligosymptomatic, 7 polysymptomatic dogs. The exposed female Phlebotomus perniciosus a local colony d later fed females dissected in order determine their rate infection. There wide variability percentage infected within each group dogs, with no...
ABSTRACT Genetic analysis of the SAG2 locus was performed to determine prevalence different genotypes Toxoplasma gondii (strain types I, II, and III) associated with human toxoplasmosis in Spain. This determination made directly from primary clinical samples, obviating previous process isolation mice or cell culture. A total 34 isolates T. , collected immunocompromised patients congenital infection cases, were analyzed. Restriction fragment length polymorphism PCR-amplified products used...
Six naturally infected dogs [two with no signs of leishmaniasis ('asymptomatic'), two a few ('oligosymptomatic') and many ('polysymptomatic')] were studied before after chemotherapy. Another two, non-infected kept as controls. The clinically, haematologically parasitologically five times over 11 months their infectivity to sandflies was evaluated the treatment. 'asymptomatic' infective 'symptomatic' treatment but all un-infective for at least following Treatment led temporary improvement in...
Suman Rijal and colleagues highlight lessons from a regional collaboration to eliminate visceral leishmaniasis identify priorities for the post-elimination plan
Abstract Background On the Indian subcontinent, visceral leishmaniasis (VL) incidence is on track to reach elimination goals by 2020 in nearly all endemic districts. Although not included official targets, previous data suggest post-kala-azar dermal (PKDL) patients can act as an infection reservoir. Methods We conducted xenodiagnosis 47 PKDL and 15 VL using laboratory-reared Phlebotomus argentipes. In direct xenodiagnosis, flies were allowed feed patient’s skin for minutes. For indirect fed...
The current evidence-base for recommendations on the treatment of cutaneous leishmaniasis (CL) is generally weak. Systematic reviews have pointed to a general lack standardization methods conduct and analysis clinical trials CL, compounded with poor overall quality several trials. For there specific need methodologies which can be applied generally, while allowing flexibility needed cover diverse forms disease. This paper intends provide investigators guidance design, conduct, report...