A5082698292- Traumatic Brain Injury Research
- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Cardiac Arrest and Resuscitation
- Neurobiology of Language and Bilingualism
- Neuroscience and Music Perception
- Neural and Behavioral Psychology Studies
- Advanced MRI Techniques and Applications
- Traumatic Brain Injury and Neurovascular Disturbances
- Cell Image Analysis Techniques
- Mental Health Research Topics
- Advanced Neuroimaging Techniques and Applications
- Sport Psychology and Performance
- Meta-analysis and systematic reviews
- Heart Rate Variability and Autonomic Control
- Psychology of Development and Education
- Educational Strategies and Epistemologies
- Cardiovascular Syncope and Autonomic Disorders
- Speech Recognition and Synthesis
- Emergency and Acute Care Studies
- Occupational Health and Safety Research
- Intelligent Tutoring Systems and Adaptive Learning
- Second Language Acquisition and Learning
- Deception detection and forensic psychology
Princeton University
2021-2025
McMaster University
2016-2023
Vector Institute
2018-2020
MaRS
2019
Dalhousie University
2014-2015
Background/Objectives: Coma prognosis is challenging, as patient presentation can be misleading or uninformative when using behavioral assessments only. Event-related potentials have been shown to provide valuable information about a patient's chance of survival and emergence from coma. Our prior work revealed that the mismatch negativity (MMN) in particular waxes wanes across 24 h some coma patients. This "cycling" aspect presence/absence neurophysiological responses may require...
The Journal of Neuroscience launched an open peer review (OPR) initiative in late 2023 to enhance transparency and accountability scientific publishing. Analysis 740 manuscripts 1,490 reviews revealed that 81.4% authors opted share rebuttal letters, with increasing participation over time (67.6% Dec 94.4% Aug 2024). Reviewer was lower (66.8%) but stable, higher opt-in rates for longer, higher-quality reviews. Geographical analysis author reviewer institutions showed from North American...
Event-related potentials (ERPs) are tiny electrical brain responses in the human electroencephalogram that typically not detectable until they isolated by a process of signal averaging. Owing to extremely smallsize ERP components (ranging from less than 1 μV tens μV), compared background rhythms, statistical analyses ERPs predominantly carried out groups subjects. This limitation is barrier translation ERP-based neuroscience applications such as medical diagnostics. We show here support...
Concussion has been shown to leave the afflicted with significant cognitive and neurobehavioural deficits. The persistence of these deficits their link neurophysiological indices cognition, as measured by event-related potentials (ERP) using electroencephalography (EEG), remains restricted population level analyses that limit utility in clinical setting. In present paper, a convolutional neural network is extended capitalize on characteristics specific EEG/ERP data order assess for...
There has been increased effort to understand the neurophysiological effects of concussion aimed move diagnosis and identification beyond current subjective behavioral assessments that suffer from poor sensitivity. Recent evidence suggests event-related potentials (ERPs) measured with electroencephalography (EEG) are persistent markers past concussions. However, as such is limited group-level analyzes, extent which they enable detection at individual-level unclear. One promising avenue...
Up to 40% of individuals with unresponsive wakefulness syndrome (UWS) actually might be conscious. Recent attempts detect covert consciousness in behaviorally patients via neurophysiological patterns are limited by the need compare data from brain-injured healthy controls. In this report, we pilot an alternative within-subject approach using propofol perturb brain state a patient diagnosed UWS. An auditory stimulation series was presented before, during, and after exposure while high-density...
Abstract The current literature presents a discordant view of mild traumatic brain injury and its effects on the human brain. This dissonance has often been attributed to heterogeneities in study populations, aetiology, acuteness, experimental paradigms and/or testing modalities. To investigate progression brain, present employed data from 93 subjects (48 healthy controls) representing both acute chronic stages injury. concussion across different were measured using two metrics functional...
This cross-linguistic study investigated the impact of spelling errors on reading behavior in five languages (Chinese, English, Finnish, Greek, and Hebrew). Learning theories predict that correct incorrect alternatives (e.g., "tomorrow" "tommorrow") provide competing cues to sound meaning a word: The closer are each other their frequency occurrence, more uncertain reader is regarding word. An information-theoretic measure entropy was used as an index uncertainty. Based learning, we predicted...
The mismatch negativity (MMN) is considered the electrophysiological change-detection response of brain, and therefore a valuable clinical tool for monitoring functional changes associated with return to consciousness after severe brain injury. Using an auditory multi-deviant oddball paradigm, we tracked MMN responses in seventeen healthy controls over 12-h period, three comatose patients assessed 24 h at two time points. We investigated whether show fluctuations detectability full conscious...
Coma is a deep state of unconsciousness that can be caused by variety clinical conditions. Traditional tests for coma outcome prediction are based mainly on set observations. Recently, certain event-related potentials (ERPs), which transient electroencephalogram (EEG) responses to auditory, visual or tactile stimuli, have been introduced as useful predictors positive (ie, emergence). However, such require the skills neurophysiologists, who not commonly available in many settings....
The present study sought to determine: 1) whether concussed adolescents exhibited deficits in neurocognitive functioning as reflected by neurophysiological alterations; 2) if alterations could be linked supplementary data such the number of previous concussions and days since injury; 3) psychological health behavioural tests increased during diagnosis duration. Twenty-six were compared twenty-eight healthy controls with no prior concussions. Self-report inventories evaluated depressive...
<p>There has been increased effort to understand the neurophysiological effects of concussion aimed move diagnosis and identification beyond current subjective behavioral assessments that suffer from poor sensitivity. Recent evidence suggests event-related potentials (ERPs) measured with electroencephalography (EEG) are persistent markers past concussions. However, as such is limited group-level analyzes, extent which they enable detection at individual-level unclear. One promising...
Introduction: Concussive and sub-concussive blows are commonly sustained during contact sports. Through a detailed neuroimaging analysis, this pilot study aimed to determine if history of sport-related concussions exacerbated cognitive decline later in life. It was hypothesized that clinical health assessments magnetic resonance imaging (MRI) techniques would provide insight into lasting well-being, structural, microstructural, functional alterations caused by concussive injuries. Materials...
A consistent limitation when designing event-related potential paradigms and interpreting results is a lack of consideration the multivariate factors that affect their elicitation detection in behaviorally unresponsive individuals. This paper provides retrospective commentary on three influence presence morphology long-latency potentials—the P3b N400. We analyze potentials derived from electroencephalographic (EEG) data collected small groups healthy youth elderly to illustrate effect...