Mohamed H. Mahmoud

ORCID: 0000-0003-2928-3828
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Research Areas
  • Protein Interaction Studies and Fluorescence Analysis
  • Animal Diversity and Health Studies
  • Natural Fiber Reinforced Composites
  • Nanoparticles: synthesis and applications
  • Drug Transport and Resistance Mechanisms
  • Essential Oils and Antimicrobial Activity
  • Natural Antidiabetic Agents Studies
  • Advanced Nanomaterials in Catalysis
  • Helicobacter pylori-related gastroenterology studies
  • Bacteriophages and microbial interactions
  • Nanofluid Flow and Heat Transfer
  • Immune Cell Function and Interaction
  • Liver physiology and pathology
  • Computational Drug Discovery Methods
  • Mechanical Engineering and Vibrations Research
  • ZnO doping and properties
  • Electrocatalysts for Energy Conversion
  • Probiotics and Fermented Foods
  • Ethnobotanical and Medicinal Plants Studies
  • Nanomaterials for catalytic reactions
  • Plant Physiology and Cultivation Studies
  • Antibiotic Resistance in Bacteria
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Bee Products Chemical Analysis
  • Xenotransplantation and immune response

King Saud University
2016-2025

Central South University
2025

Primary Health Care
2019-2024

Centre Hospitalier Universitaire Hassan II
2024

Cairo University
2024

Paracelsus Medizinische Privatuniversität
2020-2023

Engelhardt Institute of Molecular Biology
2023

Suez Canal University
2023

University of Sheffield
2023

Damanhour University
2021

Abstract The hydrothermal synthesis is presented of copper-doped carbon dots (Cu-CDs) from citric acid, urea, and copper chloride, resulting in blue-fluorescent particles with stable emission at 438 nm when excited 340 nm. Through comprehensive spectroscopic microscopic characterization (FTIR, XPS, UV, HRTEM), the Cu-CDs demonstrated remarkable stability across varying pH levels, ionic strengths, temperatures, UV exposure. Notably, exhibit ultra-sensitive selective detection hexavalent...

10.1007/s00604-024-06939-4 article EN cc-by Microchimica Acta 2025-01-15

Guava is a nutritious fruit that has perishable behavior during storage. We aimed to determine the influences of some edible coatings (namely, cactus pear stem (10%), moringa and henna leaf (3%) extracts incorporated with gum Arabic (10%)), on guava fruits’ properties when stored under ambient refrigeration temperatures for 7, 14, 21 days. The results revealed coating (10%) only, or combined natural plant extracts, exhibited significant reduction in weight loss, decay, rot ratio. Meanwhile,...

10.3390/coatings12010090 article EN Coatings 2022-01-13

Now a days there is growing demand to generate renewable energy having environment friendly materials with widely used methods exhibiting highly productive conversion of photons into electrical power. In this article, an inorganic lead-free perovskite CsSn 0.5 Ge I 3 material utilized as absorber layer, PTAA hole transport layer (HTL) and SrTiO electron (ETL). Parameters such thickness operating temperature device varied obtain optimized photovoltaic performance parameter. The simulated...

10.1166/jno.2023.3407 article EN Journal of Nanoelectronics and Optoelectronics 2023-04-01

Continuous diabetes-associated complications are a major source of immune system exhaustion and an increased incidence infection. Diabetes can cause poor circulation in the feet, increasing likelihood ulcers forming when skin is damaged slowing healing ulcers. Whey proteins (WPs) enhance immunity during childhood have protective effect on some disorders. Therefore, this study, we investigated effects camel WP closure diabetic wounds streptozotocin (STZ)-induced type I mouse model. Diabetic...

10.1186/1471-2172-13-32 article EN cc-by BMC Immunology 2012-06-18

Non-alcoholic fatty liver disease (NAFLD) is a multifactorial with complex pathophysiology. The clinical features of NAFLD include obesity, insulin resistance (IR) and dyslipidemia. Consumption diet high in saturated fats sucrose an important factor the increasing occurrence these metabolic disorders, primarily IR. We sought to assess role high-fat, high-sucrose (HFS) promotion evaluate effects quercetin (Q), berberine (BB) o-coumaric acid (CA) on modulation disorders. Fifty male rats were...

10.1186/s12944-015-0087-1 article EN cc-by Lipids in Health and Disease 2015-07-30

Empagliflozin and metformin are widely used for the treatment of type 2 diabetes. These drugs showed marked anti-inflammatory effects in different animal models via enhancing AMPK activity. Yet, protective their combination against ulcerative colitis have not been previously investigated. The current study aimed to explore potential empagliflozin/metformin mitigate DSS-induced rat model. modulating empagliflozin on AMPK/mTOR/NLRP3 axis T cell polarization were delineated. In this study,...

10.3389/fphar.2021.719984 article EN cc-by Frontiers in Pharmacology 2021-08-16

Perovskite material is a propitious candidate for high-efficiency and cost-efficient solar cells. Inorganic organic perovskite materials show outstanding electrical optical characteristics. As an absorber layer, it attracts the researchers due to its tunable bandgap, higher carrier mobility, absorption coefficient. In this article, CH 3 NH PbI -based cell proposed with architecture FTO/TiO 2 /CH /PbS-TBAI/Carbon. The present study shows that carbon as back contact stable performance....

10.1166/sam.2023.4473 article EN Science of Advanced Materials 2023-05-01

The growing human population and abiotic stresses pose significant threats to food security, with PGPR favorable as biofertilizers for plant growth stress relief. In one study, soil samples from both cultivated uncultivated plants in various cities were used isolate rhizobacterial populations. Using 50 plants, isolated populations screened biochemical changes, PGP activities morphological characteristics. A total of 199 rhizobacteria IAA production. strain M28 produced maximum 378.44 ± 2.5...

10.1080/15592324.2025.2452331 article EN cc-by Plant Signaling & Behavior 2025-01-15

The binding of clofazimine to human serum albumin (HSA) was investigated by applying optical spectroscopy and molecular docking methods. Fluorescence quenching data revealed that binds protein with constant in the order 104 M-1, increase temperature, Stern-Volmer constants gradually decreased indicating mode be static. UV-visible spectra showed absorbance upon interaction HSA which further reveals formation drug-albumin complex. Thermodynamic parameters obtained from fluorescence indicate...

10.1080/07391102.2015.1132258 article EN Journal of Biomolecular Structure and Dynamics 2016-01-03

Propolis is one of the most promising natural products, exhibiting not only therapeutic but also prophylactic actions. has several biological and pharmacological properties, including hepatoprotective activities. The present study aimed to investigate underlying molecular mechanisms propolis against CCl4-mediated liver fibrosis.Three groups male BALB/c mice (n=15/ group) were used: group 1 comprised control mice; 2 3 injected with CCl4 for induction fibrosis. Group was then orally...

10.33594/000000140 article EN cc-by-nc-nd Cellular Physiology and Biochemistry 2019-07-25

Hepatocellular carcinoma (HCC) is a leading cause of cancer related deaths worldwide. It was suggested that albendazole (ABZ) powerful inhibitor several types. However, the bioavailability ABZ very poor. Additionally, mechanisms underlying antitumor effects may go beyond its tubulin-inhibiting activity. Therefore, we aimed to examine suspension (i.p. and p.o.) ABZ-loaded cubosomes (LC) on diethylnitrosamine-induced HCC in mice. nanoparticles exhibited mean particle size 48.17 ± 0.65 nm...

10.1016/j.biopha.2021.112029 article EN Biomedicine & Pharmacotherapy 2021-08-17

Epidemiological studies have shown that the offspring of mothers who experience diabetes mellitus during pregnancy are seven times more likely to develop health complications than do not suffer from pregnancy. The present study was designed investigate whether supplementation streptozotocin (STZ)-induced diabetic pregnant mice with thymoquinone (TQ) and lactation improves risk developing acquired by their offspring. Three groups female were used: non-diabetic control dams (CD), (DD),...

10.1186/1476-511x-12-37 article EN cc-by Lipids in Health and Disease 2013-03-18

The present study details the binding process of clofazimine to hen egg white lysozyme (HEWL) using spectroscopy, dynamic light scattering, transmission electron microscopy (TEM), and molecular docking techniques. Clofazimine binds protein with constant (Kb) in order 1.57 × 104 at 298 K. Binding is spontaneous exothermic. Molecular results suggested involvement hydrogen bonding hydrophobic interactions process. Bacterial cell lytic activity presence increased more than 40% value obtained...

10.1080/07391102.2016.1211552 article EN Journal of Biomolecular Structure and Dynamics 2016-07-11

Background . Despite the high prevalence of type 2 diabetes mellitus in Gulf countries, standards care at primary level have not been widely studied. Aim To compare results clinical indicators from American Diabetes Association (ADA) 2017 guidelines to reference benchmarks Behavioral Risk Factor Surveillance System. Materials and Methods A cross-sectional analysis electronic medical records 643 randomly selected adult patients with was undertaken. checklist enabled collection...

10.1155/2019/3519093 article EN cc-by International Journal of Endocrinology 2019-12-05

Despite the advances in our understanding of genetic and immunological basis cancer, cancer remains a major public health burden with an ever-increasing incidence rate globally. Nevertheless, increasing evidence suggests that components complement system could regulate tumor microenvironment (TME) to promote progression, recurrence, metastasis. In present study, we used integrative multi-omics analysis clinical data explore relationships between expression levels epigenetic alterations C3,...

10.3390/cancers13164124 article EN Cancers 2021-08-16
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