- Cardiac, Anesthesia and Surgical Outcomes
- Gallbladder and Bile Duct Disorders
- COVID-19 and Mental Health
- Clinical Nutrition and Gastroenterology
- Nutrition and Health in Aging
- Pancreatitis Pathology and Treatment
- Hernia repair and management
- Esophageal and GI Pathology
- Appendicitis Diagnosis and Management
- Gastrointestinal disorders and treatments
- Healthcare professionals’ stress and burnout
- Abdominal Surgery and Complications
- Enhanced Recovery After Surgery
- Colorectal Cancer Surgical Treatments
- Pancreatic and Hepatic Oncology Research
- Biliary and Gastrointestinal Fistulas
- Surgical site infection prevention
- COVID-19 Pandemic Impacts
- Anesthesia and Pain Management
- Intestinal and Peritoneal Adhesions
- Liver Disease and Transplantation
- Tracheal and airway disorders
- Diet and metabolism studies
- Surgical Sutures and Adhesives
- Nausea and vomiting management
Hospital de Especialidades
2016-2025
Mexican Social Security Institute
2016-2025
Universidad de Colima
2006-2025
Colorado State University
2024
Royal London Hospital
2024
University College London
2024
Hospital Civil de Guadalajara
2003-2023
Universidad de Guadalajara
2000-2023
University of Birmingham
2023
Biomedical Research Institute
2023
Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed vaccinate (NNV) prevent one COVID-19-related death in 1 year. NNVs were based on postoperative rates and mortality an international cohort (surgical patients), community incidence case fatality data (general population). NNV estimates stratified age (18–49,...
SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk than general populations, this study aimed to determine if peri-operative or prior were further thromboembolism. We conducted a planned sub-study and analysis from international, multicentre, prospective cohort elective emergency undergoing surgery during October 2020. Patients all specialties included. The primary outcome measure was...
The role of minimally invasive distal pancreatectomy is still unclear, and whether robotic (RDP) offers benefits over laparoscopic (LDP) unknown because large multicentre studies are lacking. This study compared perioperative outcomes between RDP LDP.A international propensity score-matched included patients who underwent or LDP for any indication in 21 European centres from six countries that performed at least 15 pancreatectomies annually (January 2011 to June 2019). Propensity score...
Abstract Depression and anxiety are common after months of social isolation, they can have a negative impact on anyone's quality life if not treated promptly appropriately. The aim this study was to determine the change online modality courses presence depression or symptoms during COVID-19 pandemic associated with difference in college student’s academic achievement. This cross-sectional survey which we used Patient Health Questionnaire-9 (PHQ-9) General Anxiety Disorder-7 (GAD-7). Also,...
We have investigated the origin of swine breeds through joint analysis mitochondrial, microsatellite, and Y-chromosome polymorphisms in a sample pigs wild boars with worldwide distribution. Genetic differentiation between was remarkably weak, likely as consequence sustained gene flow both populations. The nuclear markers evidenced existence close genetic relationship Near Eastern European making it difficult to infer their relative contributions pool modern breeds. Moreover, we shown that...
Acute pancreatitis is the most common major complication after endoscopic retrograde cholangiopancreatography (ERCP). Many drugs have been evaluated for prophylaxis, including nonsteroidal anti-inflammatory (NSAIDs), which are potent inhibitors of phospholipase A2 and play a role in pathogenesis acute pancreatitis. Rectal NSAIDs shown prospective studies to decrease incidence this complication, but indication not generalized clinical practice. The aim study was evaluate efficacy rectal...
Hypoalbuminemia is a common clinical deficiency in burn patients and associated with complications related to increased extravascular fluid, including edema, abnormal healing, susceptibility sepsis. Some prognostic scales do not include biochemical parameters, whereas others consider them together comorbidities. The purpose of this study was determine whether serum albumin can predict mortality patients.We studied ≥16 years age who had complete documentation, the Abbreviated Burn Severity...
Introducción: hiperamilasemia y pancreatitis aguda representan las complicaciones mayores más frecuentes posteriores a colangiopancreatografía retrógrada endoscópica (CPRE), apareciendo en 1-30% de los casos.Objetivo: determinar la incidencia posterior CPRE evaluar utilidad indometacina rectal para prevención estos.Material métodos: ensayo clínico controlado.Durante un periodo 12 meses se incluyeron 150 pacientes.Estos fueron divididos grupo estudio (n = 75), quienes administró 100 mg 2...
Background: The effect of parenteral GLN on recovery from severe acute pancreatitis has not been thoroughly investigated. aims this study were to determine whether improves nutrition status and immune function, its ability reduce morbidity mortality in patients with condition. Methods: In a randomized clinical trial, 44 randomly assigned receive either standard PN (n = 22) or l ‐alanyl‐ ‐glutamine‐supplemented after hospital admission. Nitrogen balance, counts leukocytes, total lymphocytes,...
Dexamethasone has been reported to reduce postoperative symptoms after different surgical procedures. We evaluated the efficacy of preoperative dexamethasone in ameliorating nausea and vomiting (PONV), pain mastectomy.In this prospective, double-blind, placebo-controlled study, 70 patients scheduled for mastectomy with axillary lymph node dissection were analyzed randomization treatment 8 mg intravenous (n = 35) or placebo 35). All underwent standardized procedures general anesthesia...
Burnout syndrome is a psychological condition that commonly affects health professionals, medical students, and others in professions with long shifts. It defined by high amount of emotional exhaustion, depersonalization, low personal job satisfaction. We aimed to determine the prevalence burnout interns establish relationships between this time type hospital at which students worked during their internship. This was survey study we used Maslach Inventory, applied fifth-year on an internship...
MEG based on optically-pumped magnetometry (OP-MEG) operates with miniaturized, wearable insulation, in contrast to massive cryogenic dewars for SQUID-MEG, and allows placement of the sensors close scalp. This more natural head motion during data recording localized signal quality comparable to, or surpassing, SQUID-MEG. However no OP-MEG system date has offered full-head coverage dense sensor packing, existing systems - as SQUID-MEG require subject be sealed a multilayer, passively-shielded...
To validate whether the platelet count/spleen size ratio can be used to predict presence of esophageal varices in Mexican patients with hepatic cirrhosis.This was an analytical cross-sectional study diagnostic test for cirrhosis and performed between February 2010 December 2011. Patients a diagnosis were included stratified using their Child-Pugh score. Biochemical parameters evaluated, ultrasound measure longest diameter spleen. The calculated analyzed determine it varices. Upper...
Facial injury in adults can commonly result fractures of the mandible. Autologous mesenchymal stem cells (AMSCs) transplantation is proposed as an alternative to conventional graft treatment improve bone regeneration. The aim was evaluate effectiveness AMSCs application mandibular reduce regeneration time and increase quality.This study a single-blind controlled clinical trial conducted patients with angle fractures. Patients were divided into two groups: group fracture reduction plus...
Abstract Domestic species allow us to study dramatic evolutionary changes at an accelerated rate due the effectiveness of modern breeding techniques and availability breeds that have undergone distinct selection pressures. We present a worldwide survey haplotype variability around known causative mutation in porcine gene IGF2, which increases lean content. genotyped 34 SNPs spanning 27 kb 237 domestic pigs 162 wild boars. Although selective process had wiped out for least haplotypes carrying...
The objective was to evaluate whether preoperative administration of dexamethasone improved postoperative nausea and vomiting (PONV), pain respiratory function tests in women undergoing conservative surgery for breast cancer. This a controlled clinical trial conducted between June 2013 October 2014. Eighty patients were evaluated. Patients received dose 8 mg (n = 40) or placebo 40). data on PONV intensity obtained forced spirometry performed, 1 hr before at 1, 6, 12 24 after surgery. Any use...
Objective To describe mortality of in-hospital patients with COVID-19 and compare risk factors between survivors non-survivors. Design Prospective cohort adult inpatients. Setting Tertiary healthcare teaching hospital in Guadalajara, Mexico. Participants All confirmed hospitalised from 25 March to 7 September 2020 were included. End study: November 2020. Primary outcome measures Patient survival analysed by the Kaplan-Meier method comparison log-rank test. Mortality multivariate Cox’s...
Understanding the learning curve of a new complex surgical technique helps to reduce potential patient harm. Current series on minimally invasive distal pancreatectomy (MIDP) are mostly small, single-center series, thus providing limited data.
Gastrocutaneous fistulas are infrequent after gastrostomy tube removal. However, if the fistulous tract remains permeable, even low-volume output can produce significant cutaneous burns. The use of biodegradable adhesives has been described, where fibrin glue is applied directly over or under guidance procedures such as upper lower gastrointestinal endoscopy fistuloscopy. We studied in five consecutive adult patients with gastrocutaneous removal, no complications that might impede...