A5038584082- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac and Coronary Surgery Techniques
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Aortic aneurysm repair treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Mechanical Circulatory Support Devices
- Coronary Interventions and Diagnostics
- Aortic Disease and Treatment Approaches
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Heart Failure Treatment and Management
- Cardiac Arrest and Resuscitation
- Cardiac Health and Mental Health
- Atrial Fibrillation Management and Outcomes
- Infective Endocarditis Diagnosis and Management
- Hemodynamic Monitoring and Therapy
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Intensive Care Unit Cognitive Disorders
- Acute Kidney Injury Research
- Cardiovascular Disease and Adiposity
- Blood transfusion and management
- Lipoproteins and Cardiovascular Health
- Potassium and Related Disorders
Liverpool Community Health NHS Trust
2023
University of Liverpool
2004-2016
Liverpool Heart and Chest Hospital
2004-2016
Manchester Academic Health Science Centre
2011-2013
University of Manchester
2011
Southport and Ormskirk Hospital NHS Trust
2011
Essex Cardiothoracic Centre
2002-2008
Manchester University NHS Foundation Trust
2007
Orthopaedic Center
2007
University of York
2007
Objective: The purpose of this study was to examine the effect peri-operative red blood cell (RBC) transfusion on 30-day and 1-year mortality following coronary artery bypass grafting (CABG). Methods: We retrospectively analysed 3024 consecutive patients who underwent isolated CABG between January 1999 December 2001. Patient records were linked National Strategic Tracing Service, which all in UK. Thirty-day derived from Kaplan–Meier curves. Confounding variables controlled for by...
To study changes in coronary artery surgery practice the years spanning publication of cardiac mortality data UK.A retrospective analysis prospectively collected from all National Health Service centres undertaking adult northwest England was carried out. Patients undergoing for first time between April 1997 and March 2005 were included. Changes observed, predicted risk adjusted (EuroSCORE) studied. Evidence risk-averse behaviour looked by examining number patients at low (EuroSCORE 0-5),...
To study the ability of logistic EuroSCORE to predict operative risk in contemporary cardiac surgery.Retrospective analysis prospectively collected data.All National Health Service centres undertaking adult surgery northwest England.All patients undergoing between April 2002 and March 2004.The predictive was assessed by analysing how well it discriminates with differing observed using area under receiver operating characteristic (ROC) curve studying is calibrated against in-hospital...
Objectives: Obesity is often perceived to be a risk factor for adverse outcomes following coronary artery bypass graft (CABG) surgery. Several studies have been unclear about the relationship between obesity and of outcomes. The aim this study was examine in-hospital CABG, while adjusting confounding factors. Methods: A total 4713 consecutive patients undergoing isolated CABG April 1997 September 2001 were retrospectively analyzed. Body mass index (BMI) used as measure grouped non-obese (BMI...
There are limited data on the impact of successful chronic total occlusion (CTO) revascularization by percutaneous coronary intervention (PCI) survival. We performed a retrospective study comparing survival between patients with and failed CTO PCI.Between January 1, 2000 June 30, 2004, 543 5803 (9.4%) underwent PCI for at our center. A was defined as an artery present least 3 months Thrombolysis in Myocardial Infarction flow grade 0 or 1. Patient records were linked to national database...
Abstract Objective Patients who have prolonged stay in intensive care unit (ICU) are associated with adverse outcomes. Such patients cost implications and can lead to shortage of ICU beds. We aimed develop a preoperative risk prediction tool for following coronary artery surgery (CABG). Methods 5,186 underwent CABG between 1st April 1997 31st March 2002 were analysed development dataset. Logistic regression was used forward stepwise technique identify factors stay; defined as staying longer...
<h3>Objectives</h3> To assess the impact of introducing a transcatheter aortic valve implantation (TAVI) service on surgical activity and outcomes. <h3>Design</h3> A retrospective analysis prospectively collected data. <h3>Setting</h3> University hospital south Manchester. <h3>Patients</h3> 815 consecutive patients undergoing isolated replacement (AVR) or coronary artery bypass grafting plus AVR from January 2006 to December 2009. Fifty who underwent TAVI 2008 <h3>Main outcome measures</h3>...
Mortality results for elective abdominal aortic aneurysm (AAA) repair are published by the Vascular Society of Great Britain and Ireland. These mortality not currently risk-adjusted. The objective this study was to develop a national risk prediction model AAA repair.Data consecutive patients undergoing from National Database between April 2008 March 2011 were analysed. Multiple logistic regression backwards selection used development. outcome measure in-hospital mortality. Model calibration...
Abstract Background There is no consensus on the best risk prediction model for mortality following elective abdominal aortic aneurysm (AAA) repair. The objective was to evaluate performance of five models using UK National Vascular Database (NVD). Methods Data AAA repairs from NVD between January 2008 and December 2010 were analysed. assessed were: Glasgow Aneurysm Score (GAS), Biochemical Haematological Outcome Model (VBHOM), physiological component Physiological Operative Severity...
To develop a multivariate prediction model for major adverse cardiac events (MACE) after percutaneous coronary interventions (PCIs) by using the North West Quality Improvement Programme in Cardiac Interventions (NWQIP) PCI Registry.All NHS centres undertaking adult PCIs north west England.Retrospective analysis of prospectively collected data on 9914 consecutive patients undergoing between 1 August 2001 and 31 December 2003. A logistic regression was undertaken, with forward stepwise...
<h3>Abstract</h3> <b>Objective</b> To study the “learning curve” associated with independent practice in coronary artery surgery. <b>Design</b> Retrospective analysis of prospectively collected data. <b>Setting</b> All NHS centres north west England that carry out cardiac surgery adults. <b>Participants</b> 18 913 patients undergoing for first time between April 1997 and March 2003, 5678 whom were operated on by 15 surgeons four years after their consultant appointment. <b>Main outcome...
To develop a multivariate prediction model for in-hospital mortality following aortic valve replacement.Retrospective analysis of prospectively collected data on 4550 consecutive patients undergoing replacement between 1 April 1997 and 31 March 2004 at four hospitals. A logistic regression was undertaken, using the forward stepwise technique, to identify independent risk factors mortality. The area under receiver operating characteristic (ROC) curve calculated assess performance model....
The aim was to develop a multivariable risk prediction model for 30-day mortality following elective abdominal aortic aneurysm (AAA) repair.Data collected prospectively on 2765 consecutive patients undergoing open and endovascular AAA repair from September 1999 October 2009 in the North West of England were split randomly into development (1936 patients) validation (829) data sets. Logistic regression analysis undertaken identify factors mortality.Ninety-eight deaths (5·1 per cent) recorded...
Objective Endoscopic vein harvesting (EVH) is increasingly used as an alternative to open (OVH) for coronary artery bypass graft (CABG) surgery. Concerns about the safety of EVH with regard midterm clinical outcomes following CABG have been raised. The objective this study was assess impact on short-term and CABG. Design This a retrospective analysis prospectively collected multi-centre data. A propensity score developed match patients who underwent those OVH. Setting Blackpool Victoria...
Several studies have shown no significantly increased risk of in-hospital mortality for obese patients after coronary artery bypass grafting (CABG). However, the effect obesity on mid-term survival has not been adequately studied. We set out to examine whether following CABG is affected by obesity.We performed a retrospective study 4713 consecutive undergoing isolated between April 1997 and September 2001. Body mass index (BMI) was used as measure obesity, with 3429 categorised non-obese...
To study the use of additive and logistic European System for Cardiac Operative Risk Evaluation (EuroSCORE) to predict mortality following adult combined coronary artery bypass grafting (CABG) valve surgery.Data were collected prospectively, from all four centres providing cardiac surgery in north west England, on 1769 consecutive patients undergoing CABG between April 1997 March 2002. Observed in-hospital was compared predicted as determined by both EuroSCORE.Observed simultaneous 8.7%,...
Off-pump coronary artery bypass (OPCAB) surgery is being increasingly reported to show better outcomes compared conventional on grafting. We examined the effect of OPCAB in-hospital mortality and morbidity, while adjusting for patient disease characteristics, in four institutions North West England.Between April 1997 March 2001, 10,941 consecutive patients underwent isolated at these institutions. Of these, 7.7% were performed off-pump. used logistic regression examine morbidity after...
Objective: As little is known about the impact of non-dialysis-dependent renal dysfunction on short-and mid-term outcomes following coronary surgery we have conducted a large multi-centre study comparing patients with no history to those preoperative dysfunction.Methods: Data was prospectively collected 19,625 consecutive undergoing isolated between 1997 and 2003 from four institutions.Sixty-seven had dialysis support prior surgery, were excluded main analysis study.The remaining 19,558...