- Cerebrospinal fluid and hydrocephalus
- Spinal Dysraphism and Malformations
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Head and Neck Surgical Oncology
- Glioma Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Lung Cancer Research Studies
- Pain Management and Opioid Use
- Musculoskeletal pain and rehabilitation
- Vascular Malformations and Hemangiomas
- Craniofacial Disorders and Treatments
- Intracranial Aneurysms: Treatment and Complications
- Nausea and vomiting management
- Spinal Hematomas and Complications
- Pelvic and Acetabular Injuries
- Lung Cancer Treatments and Mutations
- Anatomy and Medical Technology
- Fetal and Pediatric Neurological Disorders
- Anesthesia and Pain Management
- Tuberous Sclerosis Complex Research
- Spine and Intervertebral Disc Pathology
- Facial Trauma and Fracture Management
- Cancer Cells and Metastasis
- Histiocytic Disorders and Treatments
China Medical University Hospital
2011-2025
China Medical University
2014-2025
An-Nan Hospital
2017
China Medical University
2011
Abstract Malignant brain tumors consist of malignancies originated primarily within the and metastatic lesions disseminated from other organs. In spite intensive studies, malignant remain to be a medical challenge. Patient-derived organoid (PDO) can recapitulate biological features primary tumor it was derived has emerged as promising drug-screening model for precision therapy. Here we show proof-of-concept based on early clinical study entailing organoids surgically resected 26 patients...
Background/Objectives: The treatment for lumbar disc herniation (LDH) is surgical discectomy. This surgery may enhance spinal instability and exacerbate degeneration. most common options include microdiscectomy (MD), interspinous process device (IPD) implantation, percutaneous endoscopic discectomy (PELD). As few studies have compared these three procedures, this study focused on collecting data the clinical, functional, imaging outcomes of symptomatic LDH. Methods: a retrospective,...
Pseudomeningocele is the term used to describe fluid accumulation due leakage of cerebrospinal into surrounding soft tissue. It may cause complications such as cosmetic deformities, chronic meningitis, and/or impingement on vital structures resulting in neurological deficits; nevertheless, life-threatening posterior fossa cyst formation a rare event.We report case induced by pseudomeningocele with brain stem compression leading coma pupillary dilation. These symptoms occurred after an...
The massive nasopharyngeal bleeding that may accompany complicated comminuted fractures of the craniofacial bones can be controlled by pressure tamponade using an inflatable urinary Foley catheter. However, inadvertent intracranial catheter penetration poses a serious risk in such situations. Management relevant case is described, and simple preventive measure suggested.
Langerhans cell histiocytosis (LCH) is a systemic disease mainly affecting children and young adults. It can manifest as single system disorder or multi-system involvement. When the central nervous involved, hypothalamic-pituitary axis most common location affected. Herein we report rare case of in monozygotic twins both with diabetes hypophyseal masses. This first about LCH lesions.
Astragalus membranaceus (AM) is a traditional Chinese herb. Our previous study revealed that AM can enhance neurological function in patients with acute intracerebral hemorrhage. The aim of this was to investigated the effects on aneurysmal subarachnoid hemorrhage (aSAH). Eighty-eight experiencing aSAH were randomly allocated either treatment group (TG) comprising 44 patients, who received 3 g orally thrice daily for 14 days, or control (CG) placebo. Eighty-three (41 CG and 42 TG) completed...
Background: For lung cancer (LC) patients with limited brain metastases (LBM), radiosurgery (RS) was the current preferred strategy. We aimed to report our experience regarding an alternative strategy (focal conformal fractionated radiotherapy, FCFRT) for these in this cohort study. Methods: identified LC LBM treated either FCFRT or RS within 2016–2019 without prior local treatment via in-house databases. The characteristics of patients, disease, treatment, and outcome were retrospectively...
This study aimed to evaluate the functional outcomes of lumboperitoneal (LP) shunt for treatment non-obstructive hydrocephalus.We retrospectively studied clinical surgical results 172 adult patients with hydrocephalus who underwent LP surgery between June 2014 and 2019. Data regarding following were collected: pre- postoperative symptom status, third ventricle width changes, Evans index, complications. Additionally, baseline follow-up Glasgow Coma Scale (GCS) score, Outcome (GOS), Modified...
Spontaneous intracranial hypotension (SIH) is a poorly understood condition that presents with wide variety of symptoms, ranging from mild headaches to coma. It typically caused by continuous spontaneous leakage spinal cerebrospinal fluid (CSF), resulting in orthostatic headaches. However, the appropriate management refractory SIH remains unclear. A 50-year-old man presented headache followed rapid decline mental status. The imaging findings were consistent diagnosis SIH, bilateral cerebral...
Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan, R.O.C. E-mail: [email protected]