- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Trace Elements in Health
- Cerebral Palsy and Movement Disorders
- Bone fractures and treatments
- Orthopedic Surgery and Rehabilitation
- Immune cells in cancer
- Musculoskeletal synovial abnormalities and treatments
- Nail Diseases and Treatments
- Cancer Risks and Factors
- Circular RNAs in diseases
- Bone Metabolism and Diseases
- Bone and Joint Diseases
- Iron Metabolism and Disorders
- Vitamin K Research Studies
- Dermatology and Skin Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- TGF-β signaling in diseases
- Hip disorders and treatments
- Bone health and treatments
- S100 Proteins and Annexins
- Elbow and Forearm Trauma Treatment
The First People’s Hospital of Lianyungang
2018-2024
Kangda College of Nanjing Medical University
2021-2023
Nanjing Medical University
2018-2023
Xuzhou Medical College
2021-2023
Lianyungang Oriental Hospital
2021
Circular RNA circ_0136474 is a new contributor of human osteoarthritis (OA) by suppressing chondrocyte proliferation. However, its role and mechanism in OA injury remain ill defined. Herein, we performed real-time quantitative PCR to detect expression circ_0136474, microRNA (miR)-766-3p, DNA methyltransferase 3A (DNMT3A) utilized Western blotting measure protein DNMT3A, matrix metalloproteinase-1 (MMP1), MMP13, collagen II, proliferating cell nuclear antigen (PCNA) B lymphoma (Bcl)-2,...
Background: In this study, we aimed to explore whether the SRY-box transcription factor 9 (SOX9) can play protective roles against occurrence and development of osteonecrosis femoral head (ONFH) by regulating proliferation, apoptosis, osteogenic differentiation human bone marrow stromal cells (hBMSCs) via Wnt/β-catenin pathway.Methods: We used 1600 mg glucocorticoid (GC) induce hBMSCs establish an ONFH cell model performed various experiments. Reverse transcription-quantitative polymerase...
This study aims to investigate the predictive value of bone morphogenetic protein-7 (BMP-7), thromboxane A2 (TXA2), and osteoprotegerin (OPG) for prognosis patients with distal radius fractures.Between January 2021 2022, a total 124 (71 males, 53 females; mean age: 49.8±5.1 years; range, 34 68 years) fractures were included in fracture group. Healthy volunteers receiving physical examination our hospital same period control group (n=50; 29 21 50.1±5.4 35 years). The expressions BMP-7, TXA2,...
Abstract Objective: It is well documented that the macro/trace elements are associated with neurodevelopment. We aimed to investigate relationship between copper (Cu)/ zinc (Zn)/iron/calcium (Ca)/magnesium (Mg) levels and cerebral palsy (CP) risk in Chinese children by performing a meta-analysis. Method: searched PubMed, Embase, Cochrane WanFang databases from January 1985 June 2019 yield studies met our predefined criteria. Fourteen were enrolled. Standard mean differences (SMDs) of...
Steroid hormone blocking is a common treatment for tenosynovitis. However, local steroid requires careful attention to the inflammatory response, as infection can cause severe soft tissue inflammation and damage.A 46-year-old female patient received tenosynovitis of right thumb at another hospital 3 months earlier. Five days later, gradually experienced redness, swelling, pain in her hand. By day 7, symptoms worsened with increased wrist pain, finger numbness. After carpal tunnel incision,...