Haiquan Zhu

ORCID: 0000-0003-2946-3108
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About
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Research Areas
  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • Trace Elements in Health
  • Cerebral Palsy and Movement Disorders
  • Bone fractures and treatments
  • Orthopedic Surgery and Rehabilitation
  • Immune cells in cancer
  • Musculoskeletal synovial abnormalities and treatments
  • Nail Diseases and Treatments
  • Cancer Risks and Factors
  • Circular RNAs in diseases
  • Bone Metabolism and Diseases
  • Bone and Joint Diseases
  • Iron Metabolism and Disorders
  • Vitamin K Research Studies
  • Dermatology and Skin Diseases
  • Adipokines, Inflammation, and Metabolic Diseases
  • TGF-β signaling in diseases
  • Hip disorders and treatments
  • Bone health and treatments
  • S100 Proteins and Annexins
  • Elbow and Forearm Trauma Treatment

The First People’s Hospital of Lianyungang
2018-2024

Kangda College of Nanjing Medical University
2021-2023

Nanjing Medical University
2018-2023

Xuzhou Medical College
2021-2023

Lianyungang Oriental Hospital
2021

Circular RNA circ_0136474 is a new contributor of human osteoarthritis (OA) by suppressing chondrocyte proliferation. However, its role and mechanism in OA injury remain ill defined. Herein, we performed real-time quantitative PCR to detect expression circ_0136474, microRNA (miR)-766-3p, DNA methyltransferase 3A (DNMT3A) utilized Western blotting measure protein DNMT3A, matrix metalloproteinase-1 (MMP1), MMP13, collagen II, proliferating cell nuclear antigen (PCNA) B lymphoma (Bcl)-2,...

10.3389/fgene.2021.648709 article EN cc-by Frontiers in Genetics 2021-05-21

Background: In this study, we aimed to explore whether the SRY-box transcription factor 9 (SOX9) can play protective roles against occurrence and development of osteonecrosis femoral head (ONFH) by regulating proliferation, apoptosis, osteogenic differentiation human bone marrow stromal cells (hBMSCs) via Wnt/β-catenin pathway.Methods: We used 1600 mg glucocorticoid (GC) induce hBMSCs establish an ONFH cell model performed various experiments. Reverse transcription-quantitative polymerase...

10.1080/08941939.2023.2197054 article EN cc-by-nc Journal of Investigative Surgery 2023-04-19

This study aims to investigate the predictive value of bone morphogenetic protein-7 (BMP-7), thromboxane A2 (TXA2), and osteoprotegerin (OPG) for prognosis patients with distal radius fractures.Between January 2021 2022, a total 124 (71 males, 53 females; mean age: 49.8±5.1 years; range, 34 68 years) fractures were included in fracture group. Healthy volunteers receiving physical examination our hospital same period control group (n=50; 29 21 50.1±5.4 35 years). The expressions BMP-7, TXA2,...

10.52312/jdrs.2023.1043 article EN Joint Diseases and Related Surgery 2023-05-25

Abstract Objective: It is well documented that the macro/trace elements are associated with neurodevelopment. We aimed to investigate relationship between copper (Cu)/ zinc (Zn)/iron/calcium (Ca)/magnesium (Mg) levels and cerebral palsy (CP) risk in Chinese children by performing a meta-analysis. Method: searched PubMed, Embase, Cochrane WanFang databases from January 1985 June 2019 yield studies met our predefined criteria. Fourteen were enrolled. Standard mean differences (SMDs) of...

10.21203/rs.3.rs-703495/v1 preprint EN cc-by Research Square (Research Square) 2021-07-31

Steroid hormone blocking is a common treatment for tenosynovitis. However, local steroid requires careful attention to the inflammatory response, as infection can cause severe soft tissue inflammation and damage.A 46-year-old female patient received tenosynovitis of right thumb at another hospital 3 months earlier. Five days later, gradually experienced redness, swelling, pain in her hand. By day 7, symptoms worsened with increased wrist pain, finger numbness. After carpal tunnel incision,...

10.1016/j.ijscr.2023.108716 article EN International Journal of Surgery Case Reports 2023-09-03
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