A5041847366- Testicular diseases and treatments
- Cancer Genomics and Diagnostics
- Genetic factors in colorectal cancer
- Ovarian cancer diagnosis and treatment
- Prostate Cancer Treatment and Research
- Urologic and reproductive health conditions
- Fungal Infections and Studies
- Neurobiology and Insect Physiology Research
- Genital Health and Disease
- Neuroblastoma Research and Treatments
- Cancer, Lipids, and Metabolism
- Lung Cancer Treatments and Mutations
- Cancer and Skin Lesions
- Genetic Associations and Epidemiology
- Virus-based gene therapy research
- Sexual Differentiation and Disorders
- Sarcoma Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Prostate Cancer Diagnosis and Treatment
- Nail Diseases and Treatments
- Cutaneous lymphoproliferative disorders research
- Nutrition, Genetics, and Disease
- Infectious Disease Case Reports and Treatments
- Cancer-related Molecular Pathways
Universidad Autónoma de Nuevo León
2010-2023
Hospital Universitario Dr José Eleuterio Gonzalez
2011-2021
Tecnológico de Monterrey
2009-2016
Abstract Background Several viruses with known oncogenic potential infect prostate tissue, among these are the polyomaviruses BKV, JCV, and SV40; human papillomaviruses (HPVs), cytomegalovirus (HCMV) infections. Recently, Xenotropic Murine Leukemia Virus-related gammaretrovirus (XMRV) was identified in tissue a high prevalence observed cancer (PC) patients homozygous for glutamine variant of RNASEL protein (462Q/Q). Association studies R462Q allele non-XMRV have not been reported. We...
Triple-negative breast cancer (TNBC) is an aggressive subtype of tumors. Comparisons between TNBC and non-triple-negative (nTNBC) may help to differentiate key components involved in neoplasms. The purpose the study was analyze expression profile versus nTNBC tumors a homogeneous population from northeastern Mexico. A prospective 50 patients (25 25 nTNBC) conducted. Clinic parameters were equally distributed for nTNBC: age at diagnosis (51 47 years, p = 0.1), glucose level (107 mg/dl 104...
Abstract Background Prostate Cancer (PCa) is the second most frequent neoplasia in men worldwide. Previous reports suggest that prevalence of PCa Hispanic males lower than Africans (including communities with African ancestry) and Caucasians, but higher Asians. Despite these antecedents, there are few open population screenings for Latin American communities. This article describes results three consecutive urban Monterrey, Mexico. Methods After receiving approval from our University...
Ganglioneuroma is a rare, benign, neuroblastic tumor arising mainly from the central or peripheral autonomic nervous system, especially sympathetic system. The most affected anatomical sites are posterior mediastinum, retroperitoneum, adrenal gland and head neck soft tissue. In current literature, reports of ganglioneuroma diagnosed by fine-needle aspiration its cytological appearance scarce.A 5-year-old girl presented with mass in cervical region since birth. Laboratory routine tests were...
Background: Fine needle aspiration biopsy (FNAB) is a simple, sensitive, quick and inexpensive method in which operator experience essential for obtaining the best results. Methods: A descriptive study cases of Pathology Cytopathology Service University Hospital UANL (2003–2005) were analyzed. These divided into three groups: Group 1, FNAB performed by pathologist; 2, specialists who are not pathologists, 3, guided an imaging with immediate evaluation pathologist. The samples classified as...
Triple negative breast cancer (TNBC) is a subtype of heterogeneous nature that for estrogen receptor (ER), progesterone (PR) and growth factor human epidermal 2 (HER2) following immunohistochemical analysis. TNBC frequently characterized by relapse reduced survival. To date, there no targeted therapy this type cancer. Chemotherapy, radiotherapy, surgery remain as the standard treatments options. The lack target heterogeneity highlight need to seek new therapeutic In study, fresh tissue...
Rosai-Dorfman disease also known as sinus histiocytosis with massive lymphadenopathy (SHML) is characterized by distorted lymph node architecture marked dilation of lymphatic sinuses occupied numerous lymphocytes, well histiocytes vesicular nucleus and abundant clear cytoplasm phagocytized lymphocytes or plasma cells, 'emperipolesis'. This unknown etiology progresses a benign prognosis strictly only when an early diagnosis treatment made. A late generalized involvement contribute to poor...
BackgroundExcess body weight has become a major public health problem worldwide, and the burden of overweight obesity was calculated in this work from economics perspective.ObjectiveTo estimate disease attributable to among males females aged 20 years older using life lost (YLL) age-standardized YLL rates (ASYLL), rank leading causes premature death.DesignA cross-sectional study took place (2010–2014) 6,054 deaths were analyzed. Thirteen basic death associated with or included. The...
Chemerin, encoded by the retinoic acid receptor responder 2 (RARRES2) gene is an adipocytesecreted protein with autocrine/paracrine functions in adipose tissue, metabolism and inflammation a recently described function vascular tone regulation, liver, steatosis, etc. This molecule believed to represent critical endocrine signal linking obesity diabetes. There are no data available regarding evolution of RARRES2 non-human primates great apes. Expression profile orthology genes unknown aspects...
Metabolic syndrome (MS) has been associated with testicular damage. Nonalcoholic fatty liver disease (NAFLD) is a multisystemic that affects different organs, but its effect on the testes unknown. A study analyzing germ cell involvement BALB/c mice was carried out. parallel comparative conducted investigated alterations in germinal epithelium of male humans died from an unrelated acute event. The complete medical histories and histologic samples thoracic aorta, tissue, tissue deceased...
The olfactomedin-like domain (OLFML) is present in at least four families of proteins, including OLFML2A and OLFML2B, which are expressed adult rat retina cells. However, no expression their orthologous has ever been reported human baboon. aim this study was to investigate the OLFML2B ocular tissues baboons (Papio hamadryas) humans, as a key elucidate OLFML function eye physiology. cDNA detection these species performed by RT-PCR. amplicons were cloned sequenced, phylogenetically analyzed...
Metalloproteinase matrix 11 (MMP11) is a member of the metalloproteinase family, which are able to degrade extracellular components, and may serve central function in enhancement tumor-induced angiogenesis, cell migration, proliferation, apoptosis connective tissue degradation. In present study, MMP11 gene expression was investigated using reverse transcription-polymerase chain reaction 68 cases type I endometrial carcinoma, all data were analyzed association with clinical characteristics....
Fine needle aspiration biopsy (FNAB) of the skin is useful in subcutaneous lesions. Dermatophytes are almost exclusively superficial cutaneous mycoses and constitute 70-80% all 5% dermatologic consultations. Inflammatory invasive forms, as well infections that remain chronic forms or persist spite treatment, more frequent immunocompromised individuals. The clinicalpresentations these cases dermatopbytic granulomas (granuloma Wilson-Majocchi pseudomycetoma) Hadida's disease.A 17-year-old male...
Cervical carcinoma is the most common malignancy of female genital tract and represents second in women worldwide. Histologically 85 to 90% cervical cancers are squamous cell carcinoma. Osteoclastic giant rich an unusual histological variant which only 4 cases have been reported. We present case a 49-year-old woman with 6-month history irregular vaginal bleeding. Examination revealed 2.7 cm polypoid mass anterior lip uterine cervix. The patient underwent hysterectomy bilateral...
Abstract Background Male EBP disorder with neurologic defects (MEND) syndrome is an X‐linked disease caused by hypomorphic mutations in the (emopamil‐binding protein) gene. Modifier genes may explain clinical variability among individuals who share a primary mutation. Methods We studied four males (Patient 1 to Patient 4) exhibiting descending degree of phenotypic severity from family MEND syndrome. To identify candidate modifier that variability, variants homeostasis cholesterol identified...
Abstract Background Adiponectin gene ( ADIPOQ ) polymorphisms have been shown to affect adiponectin serum concentration and some associated with breast cancer (BC) risk. The aims of this study were describe the frequency single nucleotide (SNPs) in Mexican women BC determine if they show an association it. Methods DNA samples from 397 patients 355 controls tested for SNPs: rs2241766 (GT) rs1501299 by TaqMan allelic discrimination assay. Hardy–Weinberg equilibrium (HWE) was tested. Multiple...
Aspergillus is an opportunistic fungus present in humid environments, whose natural environment soil, hay and compost. It a frequent contaminant the clinical laboratory. Because of this, often inhaled, affecting those with underlying pulmonary disease or immune deficiency. Fungal genitourinary tract infections are relatively common. A rare spp cervical infection diagnosed via liquid-based cytology presented current study. The 57-year-old woman attended her annual check-up without any...
The enzyme myo-Inositol oxygenase (MIOX) is also termed ALDRL6. It a kidney-specific member of the aldo-keto reductase family. MIOX catalyzes first reaction involved in myo-inositol metabolism signaling pathway and fully expressed mammalian tissues. oxidative cleavage its epimer, D-chiro-Inositol to D-glucuronate. dioxygen-dependent C6 C1 bond achieved by utilizing Fe2+/Fe3+ binuclear iron center MIOX. This has been implicated complications diabetes, including diabetic nephropathy. gene was...
Villous adenoma is a benign neoplasm with an exceptional presentation in the renal pelvis, hence very few cases have been reported. Herein we present case of patient who presented left flank pain clinically suggestive complicated pyelonephritis, culminating simple nephrectomy villous pelvis as histopathological finding associated to presence microscopic focus intestinal-type adenocarcinoma.
Atypical mycobacteriosis of the duodenum was diagnosed by duodenal brush cytology in a woman with AIDS. Smears were fixed alcohol and stained method Papanicolaou. The cytological characteristics this disease have been described previously other specimens such as imprints or fine-needle aspirations Diff-Quik Wright's stain. We found that fixation routine Papanicolaou staining allow observation numerous foamy striated macrophages (pseudo-Gaucher cells), well negative images both within...
Bilateral testicular germ cell tumors (BTGCT) occur in 1 to 4% of patients with cancer and these, 10-15% are synchronous. Overall, BTGCT represents less than 0.5% all new cases cancer. There few reports the literature synchronous different histology. We present case a 30-year-old man who presented our genitourinary tumor unit bilateral increase volume. After initial assessment, ultrasound showed presence solid both testes. Staging studies were negative for metastatic disease. The patient was...