The COVID-19 pandemic is the first to occur in an age of hyperconnectivity. This paper presents results from online anonymous survey conducted Malay, English, and Chinese, during week Movement Control Order Malaysia (n=1075), which aimed examine public knowledge, perception communication behavior Malaysian society face a sudden outbreak social distancing measures. Although level risk positive surrounding was high, majority respondents reported receiving lot questionable information....

The COVID-19 pandemic is the first to occur in an age of hyperconnectivity. This paper presents results from online anonymous survey conducted Malay, English, and Chinese, during week Movement Control Order Malaysia (n=1075), which aimed examine public knowledge, perception communication behavior Malaysian society face a sudden outbreak social distancing measures. Although level risk positive surrounding was high, majority respondents reported receiving lot questionable information....

In an age of globalisation and hyperconnectivity, the COVID-19 pandemic has caused unprecedented sustained impact worldwide. This article discusses issues related to (science) communication at different phases epidemic timeline. We consider role for prevention from ecological perspective, taking into consideration that many emerging pathogens, including COVID-19, likely arise in part due anthropogenic changes natural environments. Communication forms early response setting scene public...

Tuberculosis (TB) is ranked among the top 10 causes of death worldwide. New biomarker-based serodiagnostics and vaccines are unmet needs stalling disease control. Antigen 60 (A60) a thermostable mycobacterial complex typically purified from Bacillus Calmette-Guérin (BCG) vaccine. A60 was historically evaluated for TB serodiagnostic vaccine potential with variable findings. Despite containing immunogenic proteins, has yet to be proteomically characterized. Here, commercial (1)...

Griff. is a plant species from the family Zingiberaceae. Coloquially known as wild ginger,

Given that breast cancer is the most prevalent form of affecting Malaysian women and its low survival rate, this study investigates possible influence support group intervention on quality life (QOL). It also examines interrelationships between QOL subdomains as research has shown emotional expression psychological physical well-being. Rasch analysis was implemented to examine perception comparability Functional Assessment Cancer Therapy General Breast scales (FACT-G FACT-B) Chronic Illness...

To conduct a proof-of-concept study on preferential binding of polymeric IgA (pIgA) using novel recombinant rabbit/human chimeric secretory component (cSC) and preliminary assessment the diagnostic potential virus-specific pIgA in discriminating acute hepatitis A, E, C (HAV, HEV, HCV) patients uninfected controls an indirect enzyme-linked immunoassay.cSC binds > 0.06 μg/ml purified human mouse with negligible cross-reactivity against IgM IgA. Virus-specific was significantly higher serum HAV...

Influence of host factors, including human immunodeficiency virus (HIV) co-infection, on the distribution and diagnostic potential previously evaluated biomarkers pulmonary tuberculosis (PTB), such as anti-antigen 60 (A60) immunoglobulin (Ig) G, anti-A60 IgA, C-reactive protein (CRP), remain unclear. Anti-A60 IgG, CRP in PTB non-PTB patient sera (n = 404, smear-positive/negative, culture-positive (SPCP/SNCP) HIV+ve/-ve) were measured by enzyme-linked immunoassay statistically analysed. In...

A series of 1ʹ-acetoxychavicol acetate analogues were synthesised and evaluated for their antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA) using broth microdilution technique. The minimum inhibitory concentration (MIC) was used to determine whether the compounds had potential as agents MRSA ATCC 43300, with (<2000 μg ml–1) tested bactericidal (MBC). Based on this assay, compound 1 exhibited potent MIC value 250 ml–1. Meanwhile, 2 13 showed moderate values...

Natural products with antimycobacterial adjuvant potential may be utilized to address the rise of multidrug-resistant tuberculosis (TB). The antioxidant-rich oil palm (Elaeis guineensis) fruit (OPF) was investigated for activity against Mycobacterium (MTB) H37Ra using bio-guided fractionation techniques, followed by determination fractional inhibition index (FIC) first-line anti-TB drugs. In vitro screening microplate Alamar blue assay showed n-hexane and chloroform partitions OPF mesocarp...

) and the lowest in North west region (7.3%, 95%CI = 5.9-8.8%).Anti-HCV prevalence significantly increased with age, reaching 7.6% (95%CI 4.9-11.1%), 55-59 years age group.It was higher rural compared to urban areas (1.4% versus 0.9%, respectively, p < 0.001) different regionally across country highest Centre (2.9%, 1.6-3.4%)and Far (0.4%, 0.2-0.9%).Finally, anti-HDV by group, found 50-54 group (26.5%, 12.9-44.7%).It comparable (14.7% 12.7%, 0.26) East (52.9%,95%CI 42.8-62.9)and South...

Abstract Despite tremendous measles incidence reduction through universal vaccination, elimination efforts rely on improved surveillance. Detection of anti-measles immunoglobulin M (IgM) by ELISA is the standard laboratory diagnostic method. However, true infection rare and seroconversion following MMR vaccination also generates IgM, which results in low positive predictive values assays settings, thus necessitating confirmatory testing. Improved tests for are a World Health Organization...

ABSTRACT Despite tremendous measles incidence reduction through universal vaccination, elimination efforts rely on improved surveillance. The detection of anti-measles immunoglobulin M (IgM) by enzyme-linked immunosorbent assay is the standard laboratory diagnostic method. However, true infection rare, and seroconversion following measles, mumps, rubella vaccination also generates IgM, which results in low positive predictive values assays settings, thus necessitating confirmatory testing....