Food and beverages rich in polyphenols with antioxidant activity are highlighted as a potential factor for risk reduction of lifestyle related diseases. This study was conducted to elucidate total polyphenol consumption from Japanese people. Total (TP) contents were measured using modified Folin-Ciocalteu method removing the interference reduced sugars by reverse-phase column chromatography. A beverage survey Tokyo Osaka areas 2004. Randomly selected male female subjects (10-59 years old, n...

Estimating polyphenol intake contributes to the understanding of polyphenols' health benefits. However, information about human is scarce, especially in elderly. This study aimed estimate dietary and major sources polyphenols determine whether there any relationship between micronutrient healthy elderly Japanese. First, 610 subjects (569 men, 41 women; aged 67.3 ± 6.1 years) completed food frequency questionnaires. We then calculated their total using our content database. Their average was...

Food and beverages rich in polyphenols have been shown to reduce the risk of non-communicable diseases. The present study estimated polyphenol levels consumption from food Japanese women. Randomly recruited housewives living area around Tokyo (n 109; aged 21-56 years; Group 1) recorded all foods they ingested for 7 d, total (TP) was based on TP content each item measured with a modified Folin-Ciocalteu method. For 1, consumed at 841 (sd 403) mg/d (range 113-1759 mg/d), were larger source (79...

Abstract Purpose Several epidemiological studies have demonstrated the health benefits of polyphenols, but associations between polyphenol intake and mortality including total major causes death remain unclear. We investigated subjects’ their from all causes, cardiovascular disease (CVD), cancer, other in a population-based cohort study Japan. Methods A 29,079 residents Takayama City, Japan were analyzed. Their dietary was assessed using validated semi-quantitative food-frequency...

Inflammation in endothelial cells induces production of inflammatory cytokines and monocytes adhesion, which are crucial events the initiation atherosclerosis. Aronia berry (Aronia meranocalpa), also called black chokeberry, contains abundant anthocyanins that have received considerable interest for their possible relations to vascular health.The aim this study was investigate whether an anthocyanin-rich extract obtained from aronia can attenuate responses cells.As a model inflammation,...

The food supply system is facing important challenges and its sustainability has to be considered. Genome-editing technology, which accelerates the development of new variety, could used achieve sustainable goals, thereby protecting environment ensuring stable production for an increasing global population. most widely genome-editing tool, CRISPR/Cas9, easy use, affordable, versatile. Foods produced by technologies have been developed worldwide create novel traits. In first half review,...

Green tea and coffee contain various bioactive compounds (e.g., polyphenols), their consumption has been proposed to decrease the risk of cardiovascular diseases. Here, we investigated associations between green that prevalence coronary artery disease (CAD) in Japanese patients. The study group was 612 patients who underwent angiography at Tokyo Medical Center July 2008 February 2017. CAD confirmed 388 patients: one-vessel (1-VD, n=166); two-vessel (2-VD, n=112); three-vessel (3-VD, n=110)....

The egg is a nutrient-dense food and contains number of antioxidants. consumption eggs has been considered to improve the balance diets, although its impact on serum cholesterol levels matter concern in many countries. Here, we conducted pilot study investigate whether daily additional an might affect lipid profiles also antioxidant status healthy subjects. Fourteen male subjects were provided with breakfasts including boiled for 4 wk. At end intervention, concentrations total (TC)...

The deciduous tree Terminalia bellirica found in Southeast Asia is extensively used traditional Indian Ayurvedic medicine for the treatment of hypertension, rheumatism, and diabetes. anti-atherogenic effect fruit has not been fully elucidated. Here, we investigated extract (TBE) on low-density lipoprotein (LDL) oxidation inflammation macrophages. TBE showed 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity (EC50: 7.2 ± 1.2 μg/mL) 15-lipoxygenase inhibitory activity. also...

Appendicolith causes acute appendicitis. However, surgical indications for appendicolith-related appendicitis have not been established. We aimed to clarify the clinical features of appendicolith-associated and determine an appropriate treatment strategy based on initial presentation.We retrospectively reviewed records 479 consecutive patients with verified therapeutic as per appendicolith status.Appendicoliths were identified in 214 (44.6%) using computed tomography. Surgery was more...

Japan has responded to the spread of COVID-19 through declaration a state emergency regulate human mobility. Although was enforced by government for prefectures, there is limited evidence as whether public complied with requests voluntary stay at home. In this study, we evaluated impact declaring on mobility during pandemic in Japan.We utilized daily data 47 prefectures Japan. Data were collected via mobile phone from February 1, 2020 April 30, 2021. Difference-in-difference analysis...

An association between the dietary intake of polyphenols and human health has been shown in many epidemiological studies. Since beverages are rich sources polyphenols, we aimed to evaluate polyphenol from Japanese individuals with a focus on differences according year, age, gender season. More than 10,000 male female subjects aged 1-99 y old participated this survey every year 1996 2013, their beverage consumption amount were calculated. Polyphenol Japan showed no tendency increase or...

Carotenoid intake is associated with low mortality and cancer risks; data on non-provitamin carotenoid limited especially in Asians. We aimed to estimate Japanese adult women. content database comprises 196 food items, including 39 fruits, 87 vegetables mushrooms, 11 seaweeds, was established using from the literature analyses of foods available Japan. surveyed these women aged 21-56 years (n=109). Total 7 carotenoids (mean±SD [range]) 7,450±3,840 (1,160-21,300) μg/day; α-carotene,...

Polyphenol intake has been estimated in some populations; however, information about day-to-day and individual differences polyphenol not well-evaluated. In this study, we aimed to examine within- between-individual variation Japanese male workers. First, 56 subjects (aged 37.9±10.4 y) completed detailed 7-d dietary records (DR). We then calculated their total using our content database the variations. also minimum number of days assessment required both rank individuals within a group...

Hyperpigmentation of the skin can occur at any age depending on etiological factors but its intensity increases during adolescence in Japanese females and gradually develops further adults. The purpose this study was to characterize that influence hyperpigmentation, including age, type dietary polyphenol sources.A cross-sectional survey healthy women aged from 30 60 years (n=244) conducted using food environmental questionnaires a VISIA™ facial photoimage analyzer.UV Pigmented Spot (PS)...

Strawberry contains many bioactive compounds such as vitamin C and polyphenols well folate, a that is especially important for women of childbearing age. We investigated the effects acute consumption strawberry on serum levels antioxidant potential low-density lipoprotein (LDL). In randomised, placebo-controlled, double-blind, crossover study, twenty-three healthy female volunteers (age 22⋅5 ± 1⋅4 years) ingested 500 g purée beverage or sugar content-matched placebo beverage. Blood samples...

The Japanese Health Ministry recently granted permission for the market distribution of genome-edited (GE) foods, yet there remains a lack full understanding among consumers regarding this technology. In study, we conducted survey to assess acceptability GE foods and examined impact providing information about on their acceptability. We web-based 3,408 aged 20-69 years, focusing three aspects: (1) commercial availability (2) consumption by others, (3) your own foods. findings revealed that...

In the Japanese official detection method for unauthorized genetically modified (GM) papayas, one of two types real-time PCR reagents with DNA polymerase (TaqMan Gene Master Mix [TaqMan Gene] or FastGene QPCR Probe Mastermix w/ROX [FastGene]) is primarily used measurement. 2022, we conducted a laboratory performance study on GM papaya line PRSV-YK, and results revealed that high threshold cycle (Cq) values PRSV-YK test were obtained using TaqMan 7500 Fast & Real-Time System (ABI7500)...

Since the establishment of procedures for safety assessment food products that use recombinant DNA technology, manufacture, import, and sale genetically modified (GM) foods have not undergone are prohibited under Food Sanitation Act. Therefore, a performance study to confirm GM testing operations each laboratory is very important ensure reliability monitoring system. In 2022, papaya line PRSV-YK-which has yet been authorized in Japan-was selected testing, paste solution were used as test...

Cells regularly repair numerous mutations. However, the effect of CRISPR/Cas9-induced dsDNA breaks on processes naturally occurring genome-wide mutations is unclear. In this study, we used TSCE5 cells with heterozygous thymidine kinase genotype (TK