Harriet L Lancaster

ORCID: 0000-0003-3025-9745
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About
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Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Lung Cancer Treatments and Mutations
  • Medical Imaging Techniques and Applications
  • COVID-19 diagnosis using AI
  • Renal and Vascular Pathologies
  • Bladder and Urothelial Cancer Treatments
  • Renal Transplantation Outcomes and Treatments
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Gastric Cancer Management and Outcomes
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • AI in cancer detection
  • Organ Donation and Transplantation

University Medical Center Groningen
2021-2025

University of Groningen
2021-2025

ObjectiveTo evaluate performance of AI as a standalone reader in ultra-low-dose CT lung cancer baseline screening, and compare it to that experienced radiologists.Methods283 participants who underwent ultra-LDCT scan Moscow Lung Cancer Screening, between February 2017–2018, had at least one solid nodule, were included. Volumetric nodule measurements performed by five blinded radiologists, independently assessed using an screening prototype (AVIEW LCS, v1.0.34, Coreline Soft, Co. ltd, Seoul,...

10.1016/j.lungcan.2022.01.002 article EN cc-by Lung Cancer 2022-01-06

We investigated whether presence and characteristics of lung nodules in the general population using low-dose computed tomography (LDCT) varied by season. Imaging Lifelines (ImaLife) study participants who underwent chest LDCT-scanning between October 2018 2019 were included this sub-study. Hay fever season (summer) was defined as 1st April to 30th September Influenza (winter) 31st March. All with volume ≥ 30 mm3 (approximately 3 mm diameter) registered. In total, 2496 found 1312 (38%) 3456...

10.1038/s41598-021-88328-y article EN cc-by Scientific Reports 2021-04-28

Renal endothelial cells (ECs) play crucial roles in vasorelaxation, ultrafiltration, and selective transport of electrolytes water, but also leakage the glomerular filtration barrier inflammatory processes like complement activation leukocyte recruitment. In addition, they are target for both cellular antibody-mediated rejection transplanted kidney. To study molecular underlying EC behavior renal disease, well-characterized primary ECs indispensible. this report, we describe a...

10.1152/ajprenal.00541.2020 article EN AJP Renal Physiology 2021-03-15

Abstract We evaluated the impact of influenza season on outcome new lung nodules in a LDCT cancer screening trial population. NELSON-trial participants with ≥ 1 nodule detected rounds two and three were included. Outcome (resolution or persistence) per was calculated compared. Winter (influenza season) defined as 1st October to 31st March, compared summer (hay-fever season), April 30th September. Overall, 820 reported 529 participants. Of total nodules, 482 (59%) during winter. When...

10.1038/s41598-023-33672-4 article EN cc-by Scientific Reports 2023-04-21
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