A5016295014- Photoreceptor and optogenetics research
- Neural dynamics and brain function
- Neuroendocrine regulation and behavior
- Psychological Well-being and Life Satisfaction
- Evolutionary Game Theory and Cooperation
- Retinal Development and Disorders
- COVID-19 and Mental Health
- Neuroscience and Neuropharmacology Research
- Tryptophan and brain disorders
- Receptor Mechanisms and Signaling
- Long-Term Effects of COVID-19
- Neuroscience of respiration and sleep
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Treatment of Major Depression
- Stress Responses and Cortisol
Weizmann Institute of Science
2020-2024
Max Planck Institute of Psychiatry
2020-2021
Abstract The medial prefrontal cortex (mPFC) mediates a variety of complex cognitive functions via its vast and diverse connections with cortical subcortical structures. Understanding the patterns synaptic connectivity that comprise mPFC local network is crucial for deciphering how this circuit processes information relays it to downstream To elucidate organization mPFC, we developed high-throughput optogenetic method mapping large-scale functional in acute brain slices. We show male mice,...
Abstract Information is transmitted between brain regions through the release of neurotransmitters from long-range projecting axons. Understanding how activity such connections contributes to behavior requires efficient methods for reversibly manipulating their function. Chemogenetic and optogenetic tools, acting endogenous G-protein-coupled receptor pathways, can be used modulate synaptic transmission, but existing tools are limited in sensitivity, spatiotemporal precision or spectral...
Abstract The COVID-19 pandemic poses multiple psychologically stressful challenges and is associated with an increased risk for mental illness. Previous studies have focused on the psychopathological symptoms outbreak peak. Here, we examined behavioural mental-health impact of in Israel using online survey, during six weeks encompassing end first beginning second. We used clinically validated instruments to assess anxiety- depression-related emotional distress, symptoms, coping strategies,...
Abstract Background Maladaptive aggression in humans is associated with several psychiatric conditions and lacks effective treatment. Nevertheless, constitutes an essential behavior throughout the animal kingdom as long it tightly regulated. Studying how social dominance hierarchies (SDH) regulate access to resources enriched environment (EE) can narrow translational gap between models normal pathological behavior. Methods The ‘social box’ (SB) a semi-natural setup for automatic prolonged...
Information is transmitted between brain regions through the release of neurotransmitters from long-range projecting axons. Understanding how activity such connections contributes to behavior requires efficient methods for reversibly manipulating their function. Chemogenetic and optogenetic tools, acting endogenous G-protein coupled receptor (GPCRs) pathways, can be used modulate synaptic transmission, but existing tools are limited in sensitivity, spatiotemporal precision, or spectral...
Abstract The medial prefrontal cortex (mPFC) mediates a variety of complex cognitive functions via its vast and diverse connections with cortical subcortical structures. Understanding the patterns synaptic connectivity that comprise mPFC local network is crucial for deciphering how this circuit processes information relays it to downstream To elucidate organization mPFC, we developed high-throughput optogenetic method mapping large-scale functional connectivity. We show neurons project...
Abstract Background The coronavirus disease 2019 (COVID-19) pandemic poses multiple psychologically-stressful challenges and is associated with increased risk for mental illness. Previous studies have mostly focused on the psychopathological symptoms outbreak peak. Methods We examined behavioural health impact of in Israel using an online survey. collected 12,125 responses from 4,933 adult respondents during six weeks encompassing end first beginning second. used clinically validated...