A5061749009- Ocular Oncology and Treatments
- Ultrasound and Hyperthermia Applications
- Advanced Radiotherapy Techniques
- Glaucoma and retinal disorders
- Photoacoustic and Ultrasonic Imaging
- Radiation Dose and Imaging
- Cutaneous Melanoma Detection and Management
- Radiation Therapy and Dosimetry
- Urinary Bladder and Prostate Research
- Optical properties and cooling technologies in crystalline materials
- Glioma Diagnosis and Treatment
- Retinal Development and Disorders
- Digital Radiography and Breast Imaging
- Ocular and Laser Science Research
- Medical Imaging Techniques and Applications
- Retinal and Macular Surgery
- Advanced X-ray and CT Imaging
- Ocular Infections and Treatments
- Urinary and Genital Oncology Studies
- Microwave Imaging and Scattering Analysis
- Corneal surgery and disorders
- Microbial Inactivation Methods
- Radiomics and Machine Learning in Medical Imaging
- Vascular Tumors and Angiosarcomas
- Nonmelanoma Skin Cancer Studies
University of Southern California
2015-2024
S:t Eriks Ögonsjukhus
2022
Karolinska Institutet
2022
Los Alamitos Medical Center
2018-2022
USC Norris Comprehensive Cancer Center
1991-2020
Aravind Eye Hospital
2012
The University of Texas MD Anderson Cancer Center
2011
Sherman Oaks Hospital
2011
Mission Heritage Medical Group
2011
Keck Hospital of USC
2003
Recent technological advances enable radiation therapy to be delivered in a highly conformal manner targets located almost anywhere the body. This capability has renewed clinical interest hypofractionation wherein tumor is few fractions of very large dose per fraction. Extrapolating experience from conventional regimens high important designing hypofractionated treatments. The concept biologically effective (BED) based on linear-quadratic (LQ) formulation e(-(alphaD+betaD2) useful tool for...
Dosimetry of eye plaques for ocular tumors presents unique challenges in brachytherapy. The accurate dosimetry are part related to the steep dose gradient tumor and critical structures that within millimeters radioactive sources. In most clinical applications, calculations distributions around assume a homogenous water medium full scatter conditions. Recent Monte Carlo (MC)-based eye-plaque simulations have demonstrated perturbation effects heterogeneous materials plaques, including...
During a 21-year period, 66 patients with uterine sarcomas were treated at California Medical Center. Histological diagnoses mixed mesodermal sarcoma in 32 (48%), leiomyosarcoma 24 (36%), and endometrial stromal 10 (15%) patients. The majority of (73%) had Stage I tumors. treatment consisted surgery alone 27 (41%), combination radiation therapy 36 (55%), three (4%) overall 1-, 2-, 5-year actuarial survival was 74%, 57%, 38%, respectively. for the 73%, 50%, 25%, which compared 75%, 61%, 44%...
No AccessJournal of Urology1 May 1990Transurethral Hyperthermia for Benign Prostatic Hyperplasia: Preliminary Clinical Results Michael D. Sapozink, Stuart Boyd, Melvin A. Astrahan, Gabor Jozsef, and Zbigniew Petrovich SapozinkMichael Sapozink More articles by this author , BoydStuart Boyd AstrahanMelvin Astrahan JozsefGabor Jozsef PetrovichZbigniew View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)40146-7AboutPDF ToolsAdd to favoritesDownload CitationsTrack...
Abstract Background: Although several environmental factors predict mammographic density, estimates of its heritability have been quite high. We investigated whether part the presumed might be attributed to differential sharing modifiable risk in monozygotic (MZ) and dizygotic (DZ) twins. Methods: measured percent absolute density using mammograms from 257 MZ 296 DZ twin pairs. The correlation intrapair was compared according zygosity across strata factors. Portions variance attributable...
An applicator for heating the prostate gland using a transurethral approach is described. This technique uses three microwave antennas and thermometry sensor attached to outer surface of balloon (Foley) type urological catheter. Each antenna also includes built-in thermistor control temperature balance power. The catheter assures rapid reproducible localization in prostatic urethra. two-dimensional SAR steady-state distributions surrounding tissue equivalent phantom are reported....
The University of Southern California Eye Physics plaques compare favorably with the Collaborative Ocular Melanoma Study in terms late adverse effects from radiation, metastasis, and local tumor recurrence.To review experience using Plaque Simulator software to treat choroidal melanomas outcomes published results Study.A retrospective case series 82 patients treated for medium-sized melanoma January 1, 1990, through December 30, 2010, iodine 125 treatment simulation developed at California....
No AccessJournal of Urology1 Dec 1990Transurethral Microwave Hyperthermia for Benign Prostatic Hyperplasia: Preliminary Clinical and Pathological Results L. Baert, F. Ameye, P. Willemen, J. Vandenhove, Lauweryns, M. Astrahan, Z. Petrovich BaertL. Baert More articles by this author , AmeyeF. Ameye WillemenP. Willemen VandenhoveJ. Vandenhove LauwerynsJ. Lauweryns AstrahanM. Astrahan PetrovichZ. View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)39748-3AboutPDF ToolsAdd to...
Measurements designed to separate primary and various scatter components of central axis dose the highest energy photon beam CGR Saturne 25 linear accelerator are described. This has an unusually large output variation with field size. The measurements performed both in air a water phantom, without aperture external collimator system. Results presented form relative factors for different sizes due (i) flattening filter scatter, (ii) phantom (iii) backscatter into monitor chamber, (iv)...
A muscle-stimulating material made of polyacrylamide gel (PAG) for testing various kinds hyperthermia applicators was investigated. The permittivity and conductivity dispersion PAG, as well an internal wavelength penetration depth, were in good agreement with those actual muscle at frequencies between 500 MHz 3 GHz. single formula PAG covering three ISM bands, most commonly used hyperthermia, 433, 915 2450 MHz, is presented. physical properties the phantom allow any desired form or shape to...
This is an analysis of treatment results over a 23-year period in 241 patients with carcinoma the esophagus. The for unresectable was external beam radiotherapy (EBRT) alone (mean dose 55 Gy) 137 (57%) combined brachytherapy 50 + 40 46 (19%), and chemotherapy 3 (1%) patients. In resectable patients, resection 9 (4%), 43 (19%) 1-, 2-, 5-year survival 36, 15, 5%, respectively (median 38 weeks). 18% (RT)-surgery (S) 11% EBRT brachytherapy, 2% alone, 0% who had S p less than 0.001. Survival...
A new applicator for intraurethral hyperthermic treatment of benign prostatic hyperplasia is described. The uses an insulated helical antenna wound on the outer surface a silicone urological (Foley) balloon catheter. catheter assures rapid and reproducible localization in urethra. Two small cannulae are fixed to exterior applicator. One holds temperature control sensor at location, other used map along Two-dimensional SAR steady-state distributions measured plane tangent tissue-equivalent...
The efficacy of localized current field (LCF) hyperthermia as an adjunct to 192Ir interstitial implantation tumors is currently under investigation. In this article, we describe experimental LCF system suitable for such investigations, and discuss some the physical biological parameters pertinent its design safe operation.
Episcleral plaques containing 125I sources are often used in the treatment of ocular melanoma. Within four years post-treatment, however, majority patients experience some visual loss due to radiation retinopathy. The high incidence late complications suggests that careful optimization may lead improved outcome. goal would be reduce magnitude vision-limiting without compromising tumor control. We have developed a three-dimensional computer model for ophthalmic plaque therapy which permits us...