In coronary artery disease (CAD), an alternative way of improvement blood circulation in the ischemic area myocardium is collateral circulation. Our study aimed to investigate rheological parameters and nitric oxide (NO) content patients with various degrees development likelihood influence fluidity on angiogenesis.We studied stable CAD who underwent elective angiography a control group same mean age. We investigated different developing collaterals those without them. patients, plasma...

Prevention of Type 2 diabetes mellitus (T2DM) requires a modifying effect on the pathological processes inducing β-cell dysfunction.the comprehensive study violation rheological parameters in patients with different stages and identification possible links between these alterations intensity oxidative stress patient's body.60 IR, prediabetes, T2DM healthy volunteers were included. Full range patients' blood - indicators erythrocytes aggregation index (EAI), relative deformability membranes...

Reinvestigate the microcirculatory alterations immediately responsible for blood rheological disorders and stases, which are related to red cell (RBC) aggregation in capillaries.Blood were produced by significantly intensified intravascular intestinal mesentery of Wistar rats cerebral cortex Chinchilla rabbits, either systemically (by administration high molecular-weight dextran) or locally increase high-molecular compounds plasma inside individual groups capillaries).Under conditions where...

Ischemic heart disease is a pathological chronic and acute condition, which provoked by insufficient blood supply or its complete cessation. To reduce the number of patients, all approaches studies that can positively affect prevention treatment are important. This very important in monitoring treating diseases systems organs, especially cardiovascular system. The aim our work was to elucidate relationship between rheological status blood, vascular changes intracardiac hemodynamics failure...

Blood loss is a complex pathological process with the mechanism that has not been fully unstudied. rheology particular link involved in blood losses. Objective: to perform comprehensive study of rheological proper ties, such as erythrocyte aggregability, deformability, plasma viscosity, and packed cell volume, different degrees experimental loss. Materials methods . stages was simulated anesthetized animals. The Georgian technique, membrane filtration, capillary method, standard...

Since the role of microvascular rheological disorders has been so far insufficiently analysed in development stroke, we examined course acute stage ischemic brain infarcts most essential feature - erythrocyte aggregabilit

The aim of this study was revealing the temperature changes in rats' brain tissue caused by whole body hyperthermia. analysis received results allows to conclude that has a highly secured system autoregulation against exogenous changes. upper limit (for rats, at least) is range 45°C environment. An important role normal functioning belongs Nitric Oxide. behavioral disorders, observed animals after hyperthermia (sure within autoregulation) are hardly associated with Central Nervous System,...

The functioning of the thyroid gland is a multi-component process that in some conditions may undergo alterations. part endocrine system produces iodine-containing hormones thyroxine and triiodothyronine. Thyroid hormones, control metabolism energy, growth processes, maturation tissues organs, regulation blood flow, and, therefore, providing vital functions body. role flow determined by intensity their production quantity blood. Presumably, case oncological non-oncological diseases gland,...

Abstract Funding Acknowledgements Type of funding sources: Public Institution(s). Main source(s): Academician N. Kipshidze University Clinic - Republican Hospital; IVANE BERITASHVILI CENTER OF EXPERIMENTAL BIOMEDICINE, Department rheology and diagnostic analytical services. Introduction Despite all biomedical efforts, the prevalence atrial fibrillation its associated morbidity mortality are increasing globally year after year. The disease's unfavorable epidemiological picture determined...

"Slow flow" is one very important concept in modern fundamental and clinical biomedicine. Slow coronary flow indicative of delayed filling the terminal artery vessels, occurring absence significant stenosis. This group patient patients exhibits a high incidence disability represents financial material burden for state healthcare system general.

BACKGROUND: Limb-threatening ischemia is one of more important problem fundamental and practice modern angiology. Despite the development diagnostic therapeutic approaches good results, Limb-Threatening Ischemia deserves special attention occupies a place among medical, biomedical socio-economic problems. A comprehensive study will make it possible to develop new approaches, result which should be decrease in total number diseases, as well minimization complications leading large-scale...

Research of resistive vessels, assessment their functional state is one the key issues blood circulation from point view physics, angiology, rheology, biomechanics and related sciences. The article examined some physical quantities that describe arteries. According to results our study, such components as thickness intimal medial layer, coefficient resistance arteries Young's module turned out be interesting pathophysiological markers can reflect change in vascular wall at earliest stages,...

We studied pregnant women in the I and II trimesters a control group of 2nd phase menstrual cycle. All measured rheological properties blood, such as red blood cell aggregation, deformation, plasma viscosity, hematocrit. It turned out that changes (deterioration) advancing first trimester tend to stabilize second trimester. This says, from our point view, about participation system adaptation mechanism.