A5044780272- Plant-Microbe Interactions and Immunity
- Plant Gene Expression Analysis
- Plant Molecular Biology Research
- Plant tissue culture and regeneration
- Plant Pathogenic Bacteria Studies
- Plant Virus Research Studies
- Photosynthetic Processes and Mechanisms
- Plant Parasitism and Resistance
- Plant Stress Responses and Tolerance
- Plant pathogens and resistance mechanisms
- Plant Reproductive Biology
- Plant biochemistry and biosynthesis
- Chromosomal and Genetic Variations
- Plant Pathogens and Fungal Diseases
- CRISPR and Genetic Engineering
- Transgenic Plants and Applications
- Legume Nitrogen Fixing Symbiosis
- Plant Disease Resistance and Genetics
- RNA and protein synthesis mechanisms
- GABA and Rice Research
- Polyamine Metabolism and Applications
- Biochemical and biochemical processes
- Biofuel production and bioconversion
- Genomics and Chromatin Dynamics
- Wheat and Barley Genetics and Pathology
Max Planck Institute for Plant Breeding Research
2011-2021
Max Planck Society
2002-2015
Max Planck Institute for Chemical Ecology
2012
Faculdades Guarulhos
2010
Cluster of Excellence on Plant Sciences
2010
University of Zurich
2006
Friedrich Schiller University Jena
2006
Centre National de la Recherche Scientifique
2003
Institut für Grenzgebiete der Psychologie und Psychohygiene
1984
Plant immune responses are triggered by pattern recognition receptors that detect conserved pathogen-associated molecular patterns (PAMPs) or resistance (R) proteins recognizing isolate-specific pathogen effectors. We show in barley, intracellular mildew A (MLA) R function the nucleus to confer against powdery fungus. Recognition of fungal avirulence A10 effector MLA10 induces nuclear associations between receptor and WRKY transcription factors. The identified act as repressors...
RRS1-R confers broad-spectrum resistance to several strains of the causal agent bacterial wilt, Ralstonia solanacearum. Although genetically defined as recessive, this R gene encodes a protein whose structure combines TIR-NBS-LRR domains found in proteins and WRKY motif characteristic some plant transcriptional factors behaves dominant transgenic susceptible plants. Here we show that PopP2, R. solanacearum type III effector, which belongs YopJ/AvrRxv family, is avirulence recognized by...
In Arabidopsis , WRKY factors comprise a large gene family of plant-specific transcriptional regulators controlling several types plant stress responses. To understand the regulatory role proteins during such processes, we identified targets senescence- and defense-associated WRKY6 factor. was found to suppress its own promoter activity as well that closely related member, indicating negative autoregulation. On other hand, positively influenced pathogen PR1 activity, most likely involving...
Abstract The Arabidopsis (Arabidopsis thaliana) transcription factor WRKY33 is essential for defense toward the necrotrophic fungus Botrytis cinerea. Here, we aimed at identifying early transcriptional responses mediated by WRKY33. Global expression profiling on susceptible wrky33 and resistant wild-type plants uncovered massive differential reprogramming upon B. cinerea infection. Subsequent detailed kinetic analyses revealed that loss of function results in inappropriate activation...
Pathogen-inducible plant promoters contain multiple cis-acting elements, only some of which may contribute to pathogen inducibility. Therefore, we made defined synthetic containing tetramers a single type element and present evidence that range elements (boxes W1, W2, GCC, JERE, S, Gst1, D) can mediate local gene expression in planta after attack. The patterns the were monitored during interactions with number pathogens, including compatible, incompatible, nonhost interactions....
Abstract Transcription factors are believed to play a pivotal role in the activation and fine-tuning of plant defense responses, but little is known about exact function individual transcription this process. We analyzed IId subfamily WRKY regulation basal resistance Pseudomonas syringae pv tomato (Pst). The expression four members was induced upon challenge with virulent avirulent strains Pst. Mutant analyses revealed that loss WRKY11 increased toward Pst further enhanced wrky11 wrky17...
Summary The enzyme 4‐coumarate:CoA ligase (4CL) plays a key role in channelling carbon flow into diverse branch pathways of phenylpropanoid metabolism which serve important functions plant growth and adaptation to environmental perturbations. Here we report on the cloning 4CL gene family from Arabidopsis thaliana demonstrate that its three members, At4CL1 , At4CL2 At4CL3 encode isozymes with distinct substrate preference specificities. Expression studies revealed differential behaviour genes...
Summary WRKY proteins constitute a large family of plant‐specific transcription factors whose precise functions have yet to be elucidated. Here we show that expression one representative in Arabidopsis , AtWRKY6 is influenced by several external and internal signals often involved triggering senescence processes plant defence responses. Progressive 5′ deletions the promoter allowed separation defined regions responsible for distinct organs or upon pathogen challenge. Nuclear localization was...
WRKY transcription factors have been shown to play a major role in regulating, both positively and negatively, the plant defense transcriptome. Nearly all studied appear stereotypic binding preference one DNA element termed W-box. How specificity for certain promoters is accomplished therefore remains completely unknown. In this study, we tested five distinct Arabidopsis factor subfamily members their selectivity towards variants of W-box embedded neighboring sequences. These studies...
The Arabidopsis mutant wrky33 is highly susceptible to Botrytis cinerea. We identified >1680 Botrytis-induced WRKY33 binding sites associated with 1576 genes. Transcriptional profiling defined 318 functional direct target genes at 14 hr post inoculation. Comparative analyses revealed that possesses dual functionality acting either as a repressor or an activator in promoter-context dependent manner. confirmed known targets involved hormone signaling and phytoalexin biosynthesis, but also...
During microbial-associated molecular pattern-triggered immunity (MTI), molecules derived from microbes are perceived by cell surface receptors and upon signaling to the nucleus initiate a massive transcriptional reprogramming critical mount an appropriate host defense response. WRKY transcription factors play important role in regulating these processes. Here, we determined on genome-wide scale flg22-induced vivo DNA binding dynamics of three most prominent factors, WRKY18, WRKY40, WRKY33....
The molecular mechanisms underlying the trade-off between plant innate immunity and steroid-mediated growth are controversial. Here, we report that activation of transcription factor BZR1 is required sufficient for suppression immune signaling by brassinosteroids (BR). induces expression several WRKY factors negatively control early responses. In addition, associates with WRKY40 to mediate antagonism BR signaling. We reveal BZR1-mediated inhibition particularly relevant when fast required,...