- Peripheral Neuropathies and Disorders
- Hereditary Neurological Disorders
- Cardiovascular Effects of Exercise
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Hypertrophic osteoarthropathy and related conditions
- Multiple Myeloma Research and Treatments
- COVID-19 and healthcare impacts
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Economics and Policy
- Healthcare cost, quality, practices
- Cardiomyopathy and Myosin Studies
- Biosimilars and Bioanalytical Methods
- Blood groups and transfusion
- Cardiac Imaging and Diagnostics
- Biomedical Ethics and Regulation
- Cardiac electrophysiology and arrhythmias
- SARS-CoV-2 and COVID-19 Research
- Oral and gingival health research
- Myasthenia Gravis and Thymoma
- Autoimmune Bullous Skin Diseases
- Chronic Lymphocytic Leukemia Research
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Erythrocyte Function and Pathophysiology
Imperial College Healthcare NHS Trust
2024
London North West Healthcare NHS Trust
2020-2021
University College London
2016-2020
John Radcliffe Hospital
2020
National Hospital for Neurology and Neurosurgery
2020
Northwick Park Hospital
2020
University College London Hospitals NHS Foundation Trust
2018-2019
University College Hospital
2016
University Hospital Lewisham
2014
A 59-year-old man with no known past medical history presented to the emergency department dyspnea, abdominal pain and malaise. Clinical assessment revealed hypoxia bibasal crepitations on chest auscultation. radiograph showed extensive bilateral air space opacification involving all zones. He was hospitalized suspicion of infection novel coronavirus, SARS-CoV-2, later proven by positive RT-PCR. Blood tests multi-organ failure deranged liver function (alkaline phosphatase 611 IU/L, alanine...
<h3>Objective</h3> POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin lesions) is a paraneoplastic disorder resulting in severe neurologic disability. Understanding the clinical, laboratory, neurophysiologic, histopathologic features as well treatment responses of will assist more accurate timely diagnosis, risk stratification, effective management. <h3>Methods</h3> This was retrospective longitudinal cohort study from 1998 to March 2019, with 7,184...
Click to increase image sizeClick decrease size Disclosure statementNo potential conflict of interest was reported by the author(s).
Background: POEMS syndrome is a paraneoplastic phenomenon whose pathogenesis not fully understood, but an underlying plasmaproliferative process appears to promote cytokine release, including vascular endothelial growth factor (VEGF) which induces capillary leakage and tissue damage. High dose melphalan‐conditioned autologous stem cell transplantation (ASCT) effective therapy for patients with adequate performance status who have non‐localised disease, some relapse. Aims: To study the...