A5029954007- MRI in cancer diagnosis
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
University of California, San Diego
2021-2024
Purpose Restriction spectrum imaging (RSI) decomposes the diffusion‐weighted MRI signal into separate components of known apparent diffusion coefficients (ADCs). The number and optimal ADCs for RSI are organ‐specific determined empirically. purpose this work was to determine model breast tissues. Methods described using a linear combination multiple exponential components. A set ADC values estimated fit voxels in cancer control ROIs. Later, contributions each component were these fixed...
Diffusion-weighted (DW) echo-planar imaging (EPI) is prone to geometric distortions due B0 inhomogeneities. Both prospective and retrospective approaches have been developed decrease correct such distortions.The purpose of this work was evaluate the performance reduced-field-of-view (FOV) acquisition distortion correction methods in decreasing artifacts for breast imaging. Coverage axilla reduced-FOV DW magnetic resonance (MRI) residual were also assessed.Retrospective.Breast phantom 169...
Background Breast cancer screening with dynamic contrast‐enhanced MRI (DCE‐MRI) is recommended for high‐risk women but has limitations, including variable specificity and difficulty in distinguishing cancerous (CL) benign lesions (HRBL) from average‐risk (ARBL). Complementary non‐invasive imaging techniques would be useful to improve specificity. Purpose To evaluate the performance of a previously‐developed breast‐specific diffusion‐weighted (DW‐MRI) model (BS‐RSI3C) discrimination between...
Diffusion-weighted MRI (DW-MRI) offers a potential adjunct to dynamic contrast-enhanced discriminate benign from malignant breast lesions by yielding quantitative information about tissue microstructure. Multi-component modeling of the DW-MRI signal over an extended b-value range (up 3000 s/mm2) theoretically isolates slowly diffusing (restricted) water component in tissues. Previously, three-component restriction spectrum imaging (RSI) model demonstrated ability distinguish healthy tissue....
To date, the accuracy and variability of diffusion-weighted MRI (DW-MRI) metrics have been reported in a limited number scanner/protocol/coil combinations.To evaluate reproducibility DW-MRI estimates across multiple scanners protocols to assess effects using an 8-channel vs. 16-channel breast coil phantom.Prospective.Breast phantom containing tubes water differing polyvinylpyrrolidone (PVP) concentrations with apparent diffusion coefficients (ADCs) matching tissue.3 T (three standard one...