A5038322159- Head and Neck Surgical Oncology
- Sinusitis and nasal conditions
- Pituitary Gland Disorders and Treatments
- Obstructive Sleep Apnea Research
- Meningioma and schwannoma management
- Nasal Surgery and Airway Studies
- Tracheal and airway disorders
- Neuroscience of respiration and sleep
- Allergic Rhinitis and Sensitization
- Cerebrospinal fluid and hydrocephalus
- Asthma and respiratory diseases
- Infectious Diseases and Mycology
- Bone Tumor Diagnosis and Treatments
- Oral and Maxillofacial Pathology
- Glaucoma and retinal disorders
- Olfactory and Sensory Function Studies
- Head and Neck Cancer Studies
- Ophthalmology and Eye Disorders
- Antifungal resistance and susceptibility
- Ear Surgery and Otitis Media
- Ear and Head Tumors
- Adrenal and Paraganglionic Tumors
- Salivary Gland Tumors Diagnosis and Treatment
- Respiratory and Cough-Related Research
- Cleft Lip and Palate Research
Samsung Medical Center
2016-2025
Sungkyunkwan University
2016-2025
Peking University
2023-2025
Boramae Medical Center
2018
Seoul National University
2018
Hallym University
2018
Chuncheon Sacred Heart Hospital
2018
Pusan National University
2018
Chinese Academy of Medical Sciences & Peking Union Medical College
2012
Chinese Academy of Medical Sciences Dermatology Hospital
2012
The upper respiratory tract is compromised in the early period of COVID-19, but SARS-CoV-2 tropism at cellular level not fully defined. Unlike recent single-cell RNA-Seq analyses indicating uniformly low mRNA expression entry–related host molecules all nasal epithelial cells, we show that protein levels are relatively high and their localizations restricted to apical side multiciliated cells. In addition, provide evidence patients with COVID-19 massively detected replicated within We...
Trigeminal schwannomas are rare neoplasms with an incidence of less than 1% that require a comprehensive surgical strategy. These tumors can occur anywhere along the path trigeminal nerve, capable extending intradurally into middle and posterior fossae, extracranially orbital, pterygopalatine, infratemporal fossa. Recent advancements in endoscopic surgery have suggested more minimally invasive direct route for around Meckel's cave, including endonasal approach (EEA) transorbital superior...
Tumors involving Meckel's cave remain extremely challenging because of the surrounding complex neurovascular structures and deep-seated location. The authors investigated a new minimal-access technique using endoscopic transorbital approach (eTOA) through superior eyelid crease to middle cranial fossa lesions reviewed most useful surgical procedures pitfalls this approach.
Acute invasive fungal rhinosinusitis (AIFR) is an aggressive opportunistic infection with a high mortality rate. There are few reports that demonstrate improvement in the overall prognosis. Furthermore, definite prognostic factors related to patient survival remain unclear.The objective of this study was evaluate various clinical patients AIFR.This retrospective case series treated for AIFR between 1997 and 2013. A total 45 were enrolled analysis. We evaluated demographics, characteristics,...
Cranioorbital tumors are complex lesions that involve the deep orbit, floor of frontal bone, and lesser greater wing sphenoid bone. The purpose this study was to describe clinical ophthalmological outcomes with an endoscopic transorbital approach (TOA) in management cranioorbital involving orbit intracranial compartment.
Objectives/Hypothesis We evaluated the change in upper airway collapse according to depth of sedation during drug‐induced sleep endoscopy (DISE), as well characteristics possibly associated with that change. Study Design Prospective, single center, observational study. Methods Twenty‐nine patients were twice using DISE sedation, confirmed by bispectral index (BIS), which is a measure level consciousness. Changes site and degree obstruction at retropalatal retroglossal levels evaluated. The...
Background There have been few comparative studies on olfactory function and sinonasal-specific quality of life (QOL) after endoscopic or microscopic surgery using a transsphenoidal approach (TSA). Methods A retrospective review prospectively collected database was performed. Thirty-five patients who underwent transnasal 20 transseptal for treatment pituitary adenoma were evaluated. An anterior skull base (ASK) nasal inventory subjective visual analog scale (VAS) (0-100) olfaction evaluated...
The endoscopic endonasal approach (EEA) and the transcranial (TCA) are good options for treatment of tuberculum sellae (TS) meningiomas. objective this study was to identify key anatomical features in TS meningiomas compare two surgical approaches.
Despite medical and surgical treatments, some cases of nasal polyps (NP) exhibit recidivism. However, the endotype refractory chronic rhinosinusitis with NP (CRSwNP) remains unclear. Therefore, objective this study was to characterize immunological profile CRSwNP.The control (n =23), primary group (pNP, n =70) (rNP, =86) were enrolled in study. Patients who underwent revision surgeries due failed maximal treatment after surgery defined as rNP group. A total 18 inflammatory markers...
Olfaction has been shown to have a large impact on patients' lives. Endoscopic pituitary surgery is associated with potentially significant damage olfactory tissues. The objective of this study was determine the effect cauterization function when performing endoscopic nasoseptal "rescue" flap.A retrospective review performed prospectively collected data. primary outcome and measured using subjective visual analog scale (VAS; 0-100) Cross-Cultural Smell Identification Test (CC-SIT) before 3...
Endoscopic prelacrimal medial maxillectomy (EPMM) was previously reported to treat maxillary inverted papilloma. This study aimed compare recess approach with the conventional Caldwell-Luc (CLA) remove benign sinus tumors and evaluate usefulness of this based on our experience.Ten patients who underwent EPMM at hospital from January 2013 December 2017 were reviewed. We also reviewed 30 tumor resection via CLA during same period. From medical records, postoperative pathological results...
Nasal endoscopy is routinely performed to distinguish the pathological types of masses. There a lack studies on deep learning algorithms for discriminating wide range endoscopic nasal cavity mass lesions. Therefore, we aimed develop an endoscopic-examination-based model detect and classify lesions, including polyps (NPs), benign tumors, malignant tumors. The clinical feasibility was evaluated by comparing results those manual assessment. Biopsy-confirmed images were obtained from 17...
Pregabalin is used to treat neuropathic pain and has shown analgesic properties in postoperative pain. The aim of this study was investigate the effectiveness safety pregabalin reducing patients after septoplasty.Forty-seven scheduled for elective septoplasty were randomly assigned groups that received either (150 mg) or placebo, both one hour before surgery 12 hours initial dose. Pain (verbal numerical rating scale, VNRS) side effect assessments performed at 6, 12, 24, 24 48...
OBJECTIVE The endoscopic endonasal approach for treating primary skull base malignancies involving the clivus is a formidable task. authors hypothesized that tumor involvement of nearby critical anatomical structures creates hurdles to gross-total resection (GTR). aim this study was retrospectively review clinical outcomes patients who underwent an treat and analyze prognostic factors GTR. METHODS Between January 2009 November 2015, 42 at 2 independent institutions. Clinical data; locations...
Background Although septoplasty provides adequate correction of septal deviation, patients are not always satisfied with the procedure. The degree satisfaction after surgery may be affected by individual differences in perception one's nasal passage changes and emotional factors. aim this study is to identify predictive factors that influence subjective outcomes. Methods Forty‐nine deviation obstruction were enrolled. Forty‐three completed 3 months surgery. Age, gender, allergies, smoking,...
OBJECTIVE Orbital tumors are often surgically challenging because they require an extensive fronto-temporo-orbital zygomatic approach (FTOZ) and a multidisciplinary team to provide the best outcomes. Recently, minimally invasive endoscopic techniques via transorbital superior eyelid (ETOA) or endonasal (EEA) have been proposed as viable alternatives transcranial approaches for orbital tumors. In this study, authors investigated feasibility of 360° circumferential access both ETOA EEA....
The role of systemic inflammation has not been clearly defined in thyroid cancers. There have conflicting reports on whether inflammatory markers predictive value for We aimed to evaluate the association between and clinicopathological factors cancers assess their detail. Five hundred thirty-one patients who underwent surgery nodules were included. patient population consisted 99 individuals (18.6%) with benign 432 (81.4%) In cancers, neutrophil-to-lymphocyte ratio (NLR) was significantly...
The petrous apex (PA) is one of the most challenging areas in skull base surgery because it surrounded by numerous critical neurovascular structures. authors analyzed clinical outcomes patients who underwent endoscopic endonasal approach (EEA) and transorbital (TOA) procedures for lesions involving PA to determine perspectives proper applications these two approaches.The included younger than 80 years with were treated between May 2015 December 2019 had regular follow-up MR images available...
<h3>Background:</h3> The purpose of this study was to analyse audiological data after microvascular decompression (MVD) for hemifacial spasm (HFS), and compare the with hearing before surgery. <h3>Methods:</h3> Auditory functions were studied surgery in 698 patients who underwent an MVD intracranial portion facial nerve HFS. results expressed as average pure tone audiometry (PTA) speech discrimination score (SDS). <h3>Results:</h3> 668 (95.7%) had no loss immediately (group 1). 17 (2.4%) a...