Shared decision-making (SDM) is the process by which physician and patient collaborate to arrive at evidence-based treatment that best aligns with patient's individual goals of care. The implementation SDM practices especially important when an invasive surgical procedure among options. Ideally, variation in choice would mirror variability rather than a physician's ability communicate effectively. Potentially aiding these communication efforts, decision aids are tools gaining popularity for...

Preoperative templating software and intraoperative navigation have the potential to impact baseplate augmentation utilization increase screw length for fixation in reverse total shoulder arthroplasty (rTSA). We aimed assess their on (1) length, (2) number of screws used, (3) frequency augmented use navigated rTSA.We compared 51 patients who underwent rTSA with 63 controls conventional at a single institution. Primary outcomes included composite percentage whom 2 were baseplates.Navigation...

We aimed to describe outcomes, including shoulder motion, deltoid strength and Disabilities of Arm, Shoulder Hand scores, in 19 patients with terrible triad injuries (anterior dislocation, rotator cuff tear or greater tuberosity fracture, axillary nerve injury) who required reconstruction. The type surgery (grafting vs. transfer), demographic factors injury characteristics were not significantly associated outcomes. mean postoperative abduction score 95° 28, respectively. Patients tears had...

Rat brain creatine kinase (CKB) gene expression is highest in the but also detectable at lower levels some other tissues. In brain, CKB enzyme thought to be involved regeneration of ATP necessary for transport ions and neurotransmitters. To understand molecular events that lead high we have determined steady-state mRNA homogeneous cultures primary rat astrocytes, oligodendrocytes, neurons. Northern blot analysis showed whereas 1.4-kb was neurons, level about 17-fold higher oligodendrocytes...

We sought to evaluate early recovery from rotator cuff repair by assessing the correlation between patient resilience and postoperative shoulder pain function, physical mental health.Patients scheduled undergo arthroscopic were prospectively enrolled. Resilience was assessed using Brief Scale (BRS), function measured American Society of Shoulder Elbow Surgeons (ASES) scores, health Patient-Reported Outcome Measurement Information System Global Health-10 (PROMIS-10). All scores obtained...

Out of concern for the increased risk complications with morbid obesity, institutional body mass index (BMI) cutoffs total knee arthroplasty (TKA) have become commonplace. We sought to answer questions: what percentage morbidly obese patients osteoarthritis who present an clinic will, within 2 years, undergo TKA at (1) a BMI less than 40 kg/m2 or (2) greater kg/m2? Of those do not surgery, (3) lose enough weight TKA-eligible, and (4) not? performed observational study 288 patients, which 256...

Social media has emerged as a useful tool in the fellowship recruitment process. We aimed to assess prevalence of social use among hand surgery fellowships, analyze posts according content, and evaluate level engagement generated by specific content.We used list accredited fellowships from American Society for Surgery Hand Fellowship Directory identify all profiles on Facebook, Twitter, Instagram. Instagram was most commonly platform thus focus this study. Two reviewers independently...

We aimed to evaluate the correlation between preoperative and postoperative resilience scores outcomes at minimum 2-year follow-up after arthroscopic rotator cuff repair.

Abstract We have recently shown that while brain creatine kinase (CKB) mRNA was detectable in RNA from cultured primary rat neurons, CKB about 15‐fold higher astrocytes and 17‐fold oligodendrocytes (Molloy et al., J Neurochem 59:1925–1932, 1992). To begin to understand the molecular mechanisms responsible for glial cells containing highest levels of body, we examined expression established C6 glioma cells. RNase‐protection analysis showed endogenous exponentially growing were high measured...

Wilson, Charlie D. MD; Parsons, Miles S. Kallina, Charles F. IV Fornfeist, Douglas MDAuthor Information

The cytoplasmic creatine kinase (CKB) enzyme has a central role in the regeneration of ATP brain. We have shown previously that CKB mRNA levels cultured primary rat brain astrocytes and oligodendrocytes are much higher than neurons. It been suggested high expression is essential for energy-demanding functions glial cells. Conversely, may be repressed most neuronal cells; however, protein detected by immunohistochemistry several distinct groups neurons adult rodent Presently, little known...

Creatine kinases (CK) catalyze the reversible transfer of a high energy phosphate group between creatine and ADP to regenerate ATP in cell types where requirements for are extensive and/or sudden. Previously, we have shown primary rat brain cultures that CK (CKB) mRNA levels highest astrocytes oligodendrocytes much lower neuronal cells. However, little is known factors which regulate CKB expression central nervous system peripheral system. To begin investigate these factors, asked this...

A 14-year-old previously healthy girl presented with atraumatic onset of low back and flank pain mildly elevated inflammatory markers. Magnetic resonance imaging disclosed an L5 superior endplate fracture, cultures grew methicillin-susceptible Staphylococcus aureus. We discuss the variable presentations appropriate treatments adolescent vertebral osteomyelitis.