A5010128963- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Child Nutrition and Water Access
- Helminth infection and control
- Global Maternal and Child Health
- Parasitic Diseases Research and Treatment
- Iron Metabolism and Disorders
- Zoonotic diseases and public health
- Parasitic Infections and Diagnostics
- Hemoglobinopathies and Related Disorders
- Global Health and Surgery
- Global Health and Epidemiology
- Parasitic infections in humans and animals
- Trace Elements in Health
- Malaria Research and Control
- Breastfeeding Practices and Influences
- Health Systems, Economic Evaluations, Quality of Life
- Human Rights and Development
- Dermatological diseases and infestations
- Congenital Anomalies and Fetal Surgery
- Social Science and Policy Research
- Nematode management and characterization studies
- Pregnancy and Medication Impact
- Health and Well-being Studies
- Climate Change and Health Impacts
World Health Organization
2016-2025
World Health Organization - Pakistan
2011-2024
Drugs for Neglected Diseases Initiative
2012-2024
New York Academy of Sciences
2023
John Wiley & Sons (Germany)
2023
Moss Landing Marine Laboratories
2023
Hudson Institute
2023
ORCID
2020-2021
Hanoi School Of Public Health
2009
The University of Melbourne
2008
Strongyloidiasis is a common neglected tropical disease in and sub-tropical climatic zones. At the worldwide level, there high uncertainty about strongyloidiasis burden. This represents an important knowledge gap since it affects planning of interventions to reduce burden endemic countries. study aimed estimate global prevalence. A literature review was performed obtain prevalence data from countries at level 1990 2016. For each study, true population calculated by accounting for specificity...
Background The three major soil-transmitted helminths (STH) Ascaris lumbricoides, Trichuris trichiura and Necator americanus/Ancylostoma duodenale are among the most widespread parasites worldwide. Despite global expansion of preventive anthelmintic treatment, standard operating procedures to monitor drug efficacy lacking. objective this study, therefore, was define a single 400 milligram dose albendazole (ALB) against these STH using standardized protocol. Methodology/Principal Findings...
Soil-transmitted helminth (STH) infections are the most widespread of neglected tropical diseases, primarily affecting marginalized populations in low- and middle-income countries. More than one billion people currently infected with STHs. For control these infections, World Health Organization (WHO) recommends an integrated approach, which includes access to appropriate sanitation, hygiene education, preventive chemotherapy (i.e., large-scale, periodic distribution anthelmintic drugs)....
<h3>Abstract</h3> <b>Objective:</b> To measure the effects of iron supplementation and anthelmintic treatment on status, anaemia, growth, morbidity, development children aged 6–59 months. <b>Design:</b> Double blind, placebo controlled randomised factorial trial treatment. <b>Setting:</b> Community in Pemba Island, Zanzibar. <b>Participants:</b> 614 preschool <b>Main outcome measures:</b> Development language motor skills assessed by parental interview before after age appropriate subgroups....
Background The Kato-Katz thick smear (Kato-Katz) is the diagnostic method recommended for monitoring large-scale treatment programs implemented control of soil-transmitted helminths (STH) in public health, yet it difficult to standardize. A promising alternative McMaster egg counting (McMaster), commonly used veterinary parasitology, but rarely so detection STH human stool. Methodology/Principal Findings and methods were compared 1,543 subjects resident five countries across Africa, Asia...
Preventive chemotherapy (PC), the large-scale distribution of anthelminthic drugs to population groups at risk, is core intervention recommended by WHO for reducing morbidity and transmission four main helminth infections, namely lymphatic filariasis, onchocerciasis, schistosomiasis soil-transmitted helminthiasis. The strategy widely implemented worldwide but its general theoretical foundations have not been described so far in a comprehensive cohesive manner. Starting from information...
Neglected tropical diseases (NTDs) affect over 1 billion people. Safe water, sanitation and hygiene (WASH) contribute to prevention management of most NTDs. Linking WASH NTD interventions has potential impact on multiple NTDs can help secure sustainable equitable progress towards universal access WASH. The need address the determinants been acknowledged. In response, WHO published a new Global Strategy: 'Water, Sanitation Hygiene for accelerating sustaining Tropical Diseases'. Strategy...
Background Robust reference values for fecal egg count reduction (FECR) rates of the most widely used anthelmintic drugs in preventive chemotherapy (PC) programs controlling soil-transmitted helminths (STHs; Ascaris lumbricoides, Trichuris trichiura, and hookworm) are still lacking. However, they urgently needed to ensure detection reduced efficacies that predicted occur due growing drug pressure. Here, using a standardized methodology, we assessed FECR rate single oral dose mebendazole...
Background Because the success of deworming programs targeting soil-transmitted helminths (STHs) is evaluated through periodically assessment prevalence and infection intensities, use correct diagnostic method utmost importance. The STH community has recently published for each phase a program minimal criteria that potential needs to meet, so-called target product profiles (TPPs). Methodology We compared performance single Kato-Katz (reference method) with other microscopy-based methods...
Preventive chemotherapy interventions for the control of soil-transmitted helminthiases (STH) and schistosomiasis scaled up from a global coverage level around 5% in year 2000 to that surpassed 60% 2019. The present paper analyses concomitant reduction number disability-adjusted life years (DALYs) lost due STH during same period, 6.3 3.5 million DALYs. cumulative gain 19-year period was estimated at over 26 Given low cost intervention, our study suggests deworming is one most cost-effective...
Coprologic surveys were carried out in villages of the Behera Governorate Nile Delta region Egypt to characterize epidemiologic features human fascioliasis caused by Fasciola hepatica and F. gigantica this lowland endemic area comparison with only areas hyperendemic for disease Andean highlands South America. The prevalences detected (range = 5.2-19.0%, mean 12.8%) are highest obtained Egypt. previous results suggests that Delta, is spreading from an original situation sporadic cases...
et al., 1992). After gradual intensification of efforts over the ensuing 10 years, WHO and its member states partners are implementing a combined strategy for control schistosomiasis soil-transmitted helminths, integrated into ongoing health education initiatives (WHO, in nrenaration, a). This is summarized-in World Health Assemblv (WHA) resolution Mav 2001 KVHA. 200 1). ~l?re urges .states to ‘ensure access essential drugs against helminthiasis all services endemic areas treatment clinical...
The Ugandan national control programme for schistosomiasis has no clear policy inclusion of preschool-children (</=5 years old) children. To re-balance this health inequality, we sought to identify best diagnosis intestinal schistosomiasis, observe treatment safety and efficacy praziquantel (PZQ), extend the current WHO dose pole chemotherapy. We examined treated 363 preschool children from shoreline villages Lakes Albert Victoria, found that 62.3% (CI(95) 57.1-67.3) were confirmed have...