Chuen Zhang Lee

ORCID: 0000-0003-3107-657X
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About
Contact & Profiles
Research Areas
  • Gut microbiota and health
  • Antifungal resistance and susceptibility
  • Microbial Community Ecology and Physiology
  • Diet and metabolism studies
  • Fungal Biology and Applications
  • Indigenous Studies and Ecology
  • Genomics and Phylogenetic Studies
  • Nail Diseases and Treatments
  • Coastal wetland ecosystem dynamics
  • Genetic and phenotypic traits in livestock
  • Dietary Effects on Health
  • Bacteriophages and microbial interactions
  • Primate Behavior and Ecology
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • Fungal Infections and Studies
  • Probiotics and Fermented Foods

University of East Anglia
2023-2025

Monash University Malaysia
2021-2022

Abstract In humans, gut microbiome (GM) differences are often correlated with, and sometimes causally implicated in, ageing. However, it is unclear how these findings translate in wild animal populations. Studies that investigate GM dynamics change within individuals, with declines physiological condition, needed to fully understand links between chronological age, senescence the GM, but have rarely been done. Here, we use longitudinal data collected from a closed population of Seychelles...

10.1111/mec.17477 article EN cc-by Molecular Ecology 2024-07-16

Abstract Studies on wild animals, mostly undertaken using 16S metabarcoding, have yielded ambiguous evidence regarding changes in the gut microbiome (GM) with age and senescence. Furthermore, variation GM function has rarely been studied such populations, despite metabolic characteristics potentially being associated host senescent declines. Here, we used 7 years of repeated sampling individuals shotgun metagenomic sequencing to investigate taxonomic functional Seychelles warblers...

10.1093/ismeco/ycaf008 article EN cc-by ISME Communications 2025-01-01

The human gut contains a complex microbiota dominated by bacteriophages but also containing other viruses and bacteria fungi. There are growing number of techniques for the extraction, sequencing, analysis virome currently no standardized protocols. This study established an effective workflow to investigate stool samples from two understudied ethnic groups Malaysia: Jakun Jehai Orang Asli. By using extraction with Oxford Nanopore Technology, long-read sequencing successfully captured close...

10.1038/s41598-022-05656-3 article EN cc-by Scientific Reports 2022-02-03

Studies on wild animals, mostly undertaken using 16S metabarcoding, have yielded ambigous evidence regarding changes in the gut microbiome (GM) with age and senescence. Furthermore, variation GM function has rarely been studied such populations, despite metabolic characteristics potentially being associated host senescent declines. Here, we used seven years of longitudinal sampling shotgun metagenomic sequencing to investigate taxonomic functional Seychelles warblers (Acrocephalus...

10.32942/x2pp8r preprint EN cc-by 2024-11-14

Environmental variation is a key factor shaping microbiome communities in wild animals. However, most studies have focussed on separate populations distributed over large spatial scales. How ecological factors shape inter-individual within single landscape and host population remains poorly understood. Here, we use dense sampling of individuals natural, closed Seychelles warblers Cousin Island (<0.7 km diameter, 0.34 km2 total area) to determine whether gut exhibit high-resolution...

10.32942/x2c34k preprint EN cc-by 2024-12-14

<title>Abstract</title> Background In humans, gut microbiome (GM) differences are often correlated with, and sometimes causally implicated in, ageing. However, it is unclear how these findings translate in wild animal populations. Furthermore, studies that investigate GM dynamics change within individuals (as opposed to among individuals), with declines physiological condition, needed fully understand links between chronological age, senescence, the GM, but have rarely been done. Here, we...

10.21203/rs.3.rs-3486843/v1 preprint EN cc-by Research Square (Research Square) 2023-10-28
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