A5100343009- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Urological Disorders and Treatments
- Prostate Cancer Diagnosis and Treatment
- Anesthesia and Pain Management
- Pediatric Urology and Nephrology Studies
- Urinary Tract Infections Management
- Botulinum Toxin and Related Neurological Disorders
- Gastric Cancer Management and Outcomes
- Bariatric Surgery and Outcomes
- Anorectal Disease Treatments and Outcomes
- Colorectal Cancer Surgical Treatments
- Pancreatic and Hepatic Oncology Research
- Organ Transplantation Techniques and Outcomes
- Pain Mechanisms and Treatments
- Urinary and Genital Oncology Studies
- Liver Disease and Transplantation
- Bladder and Urothelial Cancer Treatments
- Esophageal Cancer Research and Treatment
- Surgical site infection prevention
- Vagus Nerve Stimulation Research
- Obsessive-Compulsive Spectrum Disorders
- Colorectal Cancer Screening and Detection
- Glaucoma and retinal disorders
- Food Quality and Safety Studies
Chinese Institute for Brain Research
2015-2025
Nanjing Medical University
2025
Peking University
2025
Center for Life Sciences
2025
Nanjing Brain Hospital
2025
Lanzhou University
2024
Institute of Geographic Sciences and Natural Resources Research
2024
Chinese Academy of Sciences
2024
University of Chinese Academy of Sciences
2024
Yancheng Second People's Hospital
2020-2024
Atrial fibrillation (AF) is the most common cardiac dysrhythmia associated with significant morbidity and mortality. Several small studies have reported that low serum total testosterone (TT) levels were a higher incidence of AF. In contrast, it also anabolic steroid use an increase in risk To date, no study has explored effect normalization on new AF after replacement therapy (TRT) patients testosterone.Using data from Veterans Administrations Corporate Data Warehouse, we identified...
The interstitial cells in bladder lamina propria (LP-ICs) are believed to be involved sensing/afferent signaling mucosa. Transient receptor potential (TRP) cation channels act as mechano- or chemo-sensors and may underlie some of the sensing function LP-ICs. We aimed investigate molecular functional expression TRP implicated sensory Piezo1/Piezo2 cultured LP-ICs human bladder. Bladder tissues were obtained from patients undergoing cystectomy. isolated cultured, used for real-time reverse...
In patients with neurogenic bladder (NB), elevated intravesical pressures can be transmitted to the upper urinary tract, causing hydronephrosis (HN) and ureteral dilation (UD), which are referred as tract (UUTD). Ureteral obstruction at wall is another cause for UUTD, but less of a concern. UUTD lead chronic renal failure. Therefore, evaluation protection UUT function extremely important in management NB. Currently, most common method by detect HN UD ultrasonography (US). The Society Fetal...
Animal models are crucial for elucidating the pathological mechanisms underlying Parkinson's disease (PD). Unfortunately, most of transgenic mouse fail to manifest changes observed in PD patients, pending advancement research. However, mechanism this discrepancy remains elusive. Here, we provide compelling evidence that compensatory expression synaptotagmin-11 (Syt11) plays a key role concealing PD-associated phenotypes parkin knockout (KO) models. Unlike normal dopamine (DA) release and...
We explored the central pathogenesis of overactive bladder (OAB) and mechanism action sacral neuromodulation (SNM).We prospectively enrolled patients with OAB who chose SNM healthy controls (HCs). At baseline, all subjects completed a 72-hour voiding diary, symptom score prefrontal cortex functional near-infrared spectroscopy scan synchronous urodynamic monitoring. All were tested after implantation electrode, both success failure groups reevaluated. NIRS_KIT software was used to analyze...
No AccessJournal of UrologyInvestigative Urology1 Jan 2012Post-Stimulation Inhibitory Effect on Reflex Bladder Activity Induced by Activation Somatic Afferent Nerves in the Foot Guoqing Chen, Jeffrey A. Larson, P. Dafe Ogagan, Bing Shen, Jicheng Wang, James R. Roppolo, William C. de Groat, and Changfeng Tai ChenGuoqing Chen Department Urology, University Pittsburgh, Pennsylvania China Rehabilitation Research Center, School Medicine, Capital Medical University, Beijing, People's Republic ,...
There have no universally accepted criteria and been established for classification of underactive bladder (UAB) at present. Thus, the study described comprehensive clinical urodynamic characteristics UAB in patients with lower urinary tract symptoms. A total 1726 (1259 men 467 women; 6–88 years old) who were admitted to our center a diagnosis included this retrospective study. It was due type rehabilitation hospital, so higher percentage neurological included. The demographics,...
The aim of this study was to retrospectively evaluate the effectiveness intravesical electrical stimulation (IVES) on detrusor underactivity (DU). From 2009 2016, a total 105 patients with symptoms DU who were treated IVES included in retrospective study. medical records, physical examination findings, urine culture results, and video-urodynamic studies reviewed. Changes post-void residual (PVR) voiding efficiency (VE) for evaluation efficacy. Patients achieving >50% reduction PVR regarded...
Purpose We investigated the effects of different stimulation frequencies on inhibition bladder overactivity by sacral neuromodulation (SNM) in pigs. Methods Implant-driven stimulators were used to stimulate S3 spinal nerve 13 Cystometry was performed infusing normal saline (NS) or acetic acid (AA). SNM (pulse width, 210 µsec) at ranging from 5 50 Hz conducted intensity threshold which observable perianal and/or tail movement induced. Multiple cystometrograms determine micturition reflex....
Aims To compare the accuracy of using a bladder scanner to measure volume through intermittent catheterization (IC) in patients and introduce Bladder Deformation Index (BDI) develop correction method. Methods was assessed by nurse with scanner. A second catheterized patient's bladder. third measured urine 500‐mL or 1000‐mL graduated cylinder. Results Sixty one were included 590 pairs data obtained. The mean IC (332.3 ± 156.1) mL (339.1 158.8) mL. absolute difference 30.8 correlation...
There was little evidence to study the relationship between hypocalcemia and mortality among critically ill patients with intracerebral hemorrhage (ICH) aged ≥16 years. This aimed determine potential association in-hospital ICU in ICH United States.We analyzed 1,954 from e-Intensive Care Unit Collaborative Research Database divided them into non-hypocalcemia groups. Hypocalcemia defined as albumin-adjusted total calcium below 8.4 mg/dl. The primary secondary outcomes were hospital mortality,...
Sacral nerve stimulation has been used to treat overactive bladder. This study evaluated the effects of using different pulse widths on inhibition bladder overactivity by sacral (SNM) in pigs.Implant-driven stimulators were stimulate S3 spinal 7 pigs. Cystometry was performed infusing normal saline (NS) or acetic acid (AA). SNM at 64 μsec 624 conducted intensity threshold which observable perianal and/or tail movement induced. Multiple cystometrograms determine micturition reflex.AA-induced...