A5034183872- Parasites and Host Interactions
- Research on Leishmaniasis Studies
- Global Health and Epidemiology
- Amoebic Infections and Treatments
- Glycosylation and Glycoproteins Research
- Carbon and Quantum Dots Applications
- Genomic variations and chromosomal abnormalities
- RNA modifications and cancer
- Computational Drug Discovery Methods
- Carbon Nanotubes in Composites
- Hepatitis Viruses Studies and Epidemiology
- Global Health Workforce Issues
- Monoclonal and Polyclonal Antibodies Research
- Advanced Biosensing Techniques and Applications
- Global Maternal and Child Health
- Genomics and Rare Diseases
- Graphene and Nanomaterials Applications
North-West University
2023-2025
Tshwane University of Technology
2022-2024
University of Zimbabwe
2019-2023
Abstract King-Denborough Syndrome (KDS) is a congenital myopathy (CM) characterised by myopathy, dysmorphic features and susceptibility to malignant hyperthermia. The objective of this study was investigate the genotype-phenotype correlation in Black African patients presenting with CM, specifically those KDS-like phenotypes, who remained undiagnosed for over 25 years. A cohort 67 CM studied, whom 44 were clinically evaluated diagnosed KDS. Whole-exome sequencing (WES) performed as part an...
Schistosomiasis is a neglected tropical disease affecting over 250 million people worldwide. The the second most prevalent after malaria. Treatment of schistosomiasis relies on administration praziquantel (also known as biltricide). Reliance single drug poses threat to public health system parasite may become resistant shown by some laboratory findings. possibility resistance rising clinically significant levels has motivated scientific community search for new nominees. For long time,...
Globally, about 779 million people are estimated to be at risk of developing schistosomiasis and around 250 infected. There 120 asymptomatic 20 with severe disease. Schistosomiasis causes the highest morbidity mortality among school-aged children. The main objective study was determine prevalence burden in Mount Darwin Makoni Districts. Five hundred children from both schools aged 6–13 were included study. Urinary diagnosed using urinary filtration method presence egg(s) under microscopy...
The promoter region of human interleukin-10 (IL-10) gene is highly polymorphic while the first intronic interferon gamma (IFN-ï§) also polymorphic. These polymorphisms are associated with susceptibility or resistance to Schistosoma haematobium infection. Schistosomiasis known be a inflammatory disease that requires delicate balance pro- and anti-inflammatory cytokines. low, moderate high cytokine production resulting in exacerbation infection leading pathological severity. Urine filtration...