Microalgae have gained enormous consideration from scientific community worldwide emerging as a viable feedstock for renewable energy source virtually being carbon neutral, high lipid content, and comparatively more advantageous to other sources of biofuels. Although microalgae are seen valuable in majority part the world production biofuels bioproducts, still they unable accomplish sustainable large-scale algal biofuel production. Wastewater has organic inorganic supplements required...

With globalisation and growing health risks of synthetic colourants, search for pigments from natural sources has increased owing to their non-toxic nature. The present study highlights the bioprospection pigment a cold adapted fungal strain Penicillium sp. (GBPI_P155), isolated soil Indian Himalayan region. fungus produced insoluble orange-coloured in liquid medium with maximum production recorded potato dextrose (PD) broth at 15°C 3 pH, while biomass was 25°C pH 3. While examining effect...

Diabetes mellitus (DM) is a complicated metabolic disorder with several enzymes, including α-amylase and α-glycosidase. The responsible for postprandial glucose levels; therefore, inhibiting its activity helpful in diabetes management. Hence, to find natural inhibitors of α-amylase, we have prepared 257 phytochemical library from selected medicinal plants antidiabetic conducted virtual screening molecular dynamics study. Seventy-nine phytochemicals were screened out based on binding energy,...

An efficient protocol for hairy root induction in Berberis aristata DC. was established using two different strains of Agrobacterium rhizogenes, MTCC 532 and 2364 from IMTECH (Institute Microbial Technology), Chandigarh, India. The strain more effective than vitro grown callus (61.11 ± 1.60 % transformation frequency) found to be suitable explant comparison leaves (42.59 0.92 nodal segments (34.25 microshoots induction. presence rol A B genes during amplification confirmed the transgenic...

Production of laccase by a cold and pH tolerant strain Penicillium pinophilum has been investigated under different cultural conditions for up to 35 days incubation. The fungus was originally isolated from low temperature environment mountain ecosystem Indian Himalaya. estimations were conducted at 3 temperatures (15, 25, 35°C), range (3.5–11.5), in presence supplements including carbon nitrogen sources, vitamins, antibiotics. Optimum production recorded 25°C (optimum fungal growth) 7.5 pH....

The recent outbreak of SARS-CoV-2 disease, also known as COVID-19, has emerged a pandemic. unavailability specific therapeutic drugs and vaccines urgently demands sincere efforts for drug discovery against COVID-19. main protease (Mpro) is critical target it plays an essential role in virus replication. Therefore the identification potential inhibitors Mpro, we applied structure-based virtual screening approach followed by molecular dynamics (MD) study. A library 686 phytochemicals was...

In this study, a soil filled Hydraulic Tilting Flume (HTF) was used as test plot under simulated rainfall conditions. This flume with mollisols soils (sandy loam in texture) collected from tarai region of Himalayas. The effects root and shoot characteristics Napier grass terms leaf area index (LAI), length (SL), number leaves (NL), tillers (NT), biomass (SB), density (RD), (RL), (RB), total (TB) were investigated on runoff sediment outflow at 90, 120 150 days after planting (DAP). Four...

<title>Abstract</title> This study investigates the impact of various elicitors on production secondary metabolites in "Himalayan Toothache Relieving Tree" (<italic>Zanthoxylum armatum</italic> DC.) using <italic>in vitro</italic> shoot cultures. Five elicitors—Proline (50, 100, and 200 mg/L), Salicylic acid salt sucrose (0, 20, 40, 60 g/L), pH levels (4.0 8.0)—were tested nodal segments. The MS medium fortified with 40 g/L yielded best results, achieving highest average length (6.91 ± 0.50...

This paper compile a review on pharmacological studies, phytochemical analysis and problem associated with Zanthoxylum armatum DC. The different plant parts like leaves, fruits, stem, bark, seeds roots are used in indigenous medicine preparation against various diseases. It shows antioxidative, antitumor, antiinflammatory, analgesic, antimicrobial insecticidal/larvicidal activity. For their bioactive principles extensive chemical resulted this specie. Due to significant medicinal properties...

The leaves and fruits of Aegle marmelos (L.) have antidiabetic activity. However, the mode action molecules having activity are not known. Hence, we conducted molecular docking phytochemicals with various targets to find same. Docking prioritized Dipeptidyl peptidase-4 (DPP-4) as main target for marmelos. DPP-4 inactivates intestinal peptides, glucagon-like peptide-1 (GLP-1), Gastric inhibitory polypeptide (GIP). GLP-1 GIP stimulate a decline in blood glucose levels, but inhibits their...

Role of some auxins, indol-3-butyric acid (IBA) and α-naphthalene acetic (NAA) has been examined for their stimulatory effects on adventitious root formation in stem cuttings of Ginkgo biloba as well as subsequent growth survival these cutting raised plantlets. Lower concentration IBA (10.0 µM) was found to be the most effective treatment it not only induced maximum rooting (88.89%) but also enhanced number roots, length roots longest maximum. Further, performance plantlets, via control...

An efficient micropropagation protocol has been developed for tasar oak. Nodal segments from in vitro grown seedling were used shoot multiplication. Best multiplication response, terms of number shoots per explant as well length, was obtained woody plant (WP) medium supplemented with 6-benzyladenine and indole-3-acetic acid (8.88 μM BA + 1.43 IAA); but the establishment cultures difficult due to basal callus formation necrosis course time. Out two growth adjuvants, casein hydrolysate (CH,...